Sputum supernatant profiling reveals inflammasome-associated signatures in severe asthmatics in U-BIOPRED

Christos Rossios (London, United Kingdom), Christos Rossios, Matt Loza, Stelios Pavlidis, Antony Rowe, Ratko Djukanovic, Fred Baribaud, Peter J. Sterk, Kian Fan Chung, Ian M. Adcock, On Behalf of U-BIOPRED Study Group

Source: International Congress 2015 – Advances in the future treatment of severe asthma
Session: Advances in the future treatment of severe asthma
Session type: Oral Presentation
Number: 1773
Disease area: Airway diseases

Congress or journal article abstract

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
Christos Rossios (London, United Kingdom), Christos Rossios, Matt Loza, Stelios Pavlidis, Antony Rowe, Ratko Djukanovic, Fred Baribaud, Peter J. Sterk, Kian Fan Chung, Ian M. Adcock, On Behalf of U-BIOPRED Study Group. Sputum supernatant profiling reveals inflammasome-associated signatures in severe asthmatics in U-BIOPRED. Eur Respir J 2015; 46: Suppl. 59, 1773

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
Multi-analyte profiling of inflammatory markers in COPD sputum
Source: International Congress 2014 – Translational studies in COPD
Year: 2014

MicroRNA-146a and microRNA-155 expression in induced sputum of allergic asthmatics
Source: International Congress 2015 – The immunology of allergic airway disease
Year: 2015

Comparison of inflammatory markers in induced and spontaneous sputum in COPD patients
Source: International Congress 2014 – Translational studies in COPD
Year: 2014

Interleukin-18 levels in induced sputum of stable and exacerbated COPD patients
Source: International Congress 2014 – Translational studies in COPD
Year: 2014

Comparison of three methods for preparation of bronchiectasis sputum supernatents for biomarker measurement
Source: International Congress 2015 – Bronchiectasis and NTM infections: clinical and functional characterisation
Year: 2015

Macrophage migration inhibition factor in peripheral blood and induced sputum in patients with COPD
Source: International Congress 2014 – Basic and translational research in asthma and COPD
Year: 2014

LATE-BREAKING ABSTRACT: Sputum transcriptome analysis yields eosinophilic and non-eosinophilic inflammatory mechanisms in UBIOPRED asthma cohort
Source: International Congress 2015 – Translational research in respiratory care: new findings
Year: 2015

Activin –A and follistatin in sputum supernatant and BAL in patients with asthma
Source: Annual Congress 2013 –Systemic and airway biomarkers in respiratory diseases
Year: 2013


Metabolomic profiling of clinical sputum samples reveals novel biomarkers for the early identification of lung cancer patients
Source: International Congress 2014 – Improving diagnosis of thoracic tumours
Year: 2014

Conduct of a biomarker study in bronchiectasis patients: Correlation of neutrophil elastase activity and inflammatory load in induced sputum
Source: International Congress 2014 – Systemic and airway biomarkers
Year: 2014

Correlation of inflammatory markers of disease with sputum neutrophilia in severe asthma
Source: International Congress 2015 – Exploring mechanisms in obstructive airway diseases
Year: 2015


Sputum YKL-40 is a potential biomarker of COPD-asthma overlap
Source: International Congress 2014 – Systemic and airway biomarkers
Year: 2014


Altered circulating exosomal RNA profiles detected by next-generation sequencing in patients with severe asthma
Source: International Congress 2016 – How the understanding og molecular and genomic crosstalk is helping to diagnose lung disease
Year: 2016

Blood eosinophil count is a useful biomarker to identify patients with severe eosinophilic asthma
Source: Annual Congress 2013 –Asthma
Year: 2013

Induced sputum cytokines and chemokines and mechanistic pathways in adult asthma phenotypes
Source: Annual Congress 2013 –Asthma and COPD: diseases with different phenotypes
Year: 2013

The first U-BIOPRED sputum handprint of severe asthma
Source: International Congress 2015 – Respiratory translational research: novel mechanisms, diagnostic markers and Space Odyssey
Year: 2015



Proteome fingerprints define groups with distinct clinico-pathological phenotypes in the U-BIOPRED asthma study
Source: International Congress 2016 – What's new in biomarker analysis?
Year: 2016

Differential macrophage activation in asthmatic sputum using U-BIOPRED transcriptomics
Source: International Congress 2019 – Novel methods, diagnostics and biomarkers in chronic lung diseases
Year: 2019

High-throughput analysis of induced sputum from the U-BIOPRED study using novel proteomic and data mining approaches
Source: Annual Congress 2013 –Origins and diagnosis of asthma
Year: 2013



Sputum interleukin (IL)-13 as a biomarker for the evaluation of asthma control
Source: International Congress 2014 – Airway biomarkers
Year: 2014