Anticholinergic treatment does not affect toll-like receptor 3-induced antiviral immune response in COPD bronchial epithelial cells

Seil Sagar (Lund, Sweden), Seil Sagar, Mandy Menzel, Leif Bjermer, Lena Uller

Source: International Congress 2015 – New data on established treatments for COPD
Session: New data on established treatments for COPD
Session type: Poster Discussion
Number: 1497
Disease area: Airway diseases

Congress or journal article abstract

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
Seil Sagar (Lund, Sweden), Seil Sagar, Mandy Menzel, Leif Bjermer, Lena Uller. Anticholinergic treatment does not affect toll-like receptor 3-induced antiviral immune response in COPD bronchial epithelial cells. Eur Respir J 2015; 46: Suppl. 59, 1497

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
Effects of dexamethasone and anti-inflammatory drugs on inflammatory cytokines from bronchial epithelial cells of COPD patients
Source: International Congress 2015 – New insights into lung disease pathogenesis
Year: 2015


Platelet activating factor receptor (PAFr) expression is increased in airways of COPD patients but is not attenuated by inhaled corticosteroid (ICS)
Source: Annual Congress 2013 –COPD: new markers of diseases
Year: 2013

Azithromycin augments rhinovirus-induced expression of IFNbeta and IFNλ1 in asthmatic bronchial epithelial cells by up-regulating RIG-I like receptors
Source: International Congress 2014 – Novel evidence relating to respiratory treatment development
Year: 2014

TSPO a new anti-inflammatory target in the airway of COPD
Source: International Congress 2015 – Advances in the future treatment of COPD
Year: 2015

Repeated lipopolysaccharide stimulation causes corticosteroid insensitive inflammation in lung via phosphoinositide-3-kinase δ signaling
Source: International Congress 2014 – New treatments for cough, asthma, COPD and ILDs
Year: 2014

PTX3 a marker of innate immune responses in the airways of asthmatics and COPD patients
Source: Annual Congress 2013 –Asthma: new mechanisms and markers
Year: 2013

Evidence for cell mediated immune dysfunction in the COPD lung: The role of cytotoxic CD4+ T cells
Source: International Congress 2015 – Viral infections: basic research and clinical perspective
Year: 2015

Anti-inflammatory effects of roflumilast N-oxide and dexamethasone in human bronchial epithelial cells stimulated with toll-like receptor agonists
Source: Annual Congress 2013 –The pulmonary epithelium: recent developments
Year: 2013


Additive anti-inflammatory effect of glucocorticoids and PDE4 inhibitors on COPD CD8 cells
Source: International Congress 2014 – New treatments for cough, asthma, COPD and ILDs
Year: 2014

Macrolide effects on the prevention of COPD exacerbations
Source: Eur Respir J 2012; 40: 485-494
Year: 2012



Disease specific effects of adrenomedullin in COPD and asthma derived human bronchial epithelial cells
Source: International Congress 2015 – Immunomodulation: basic science and clinical aspects
Year: 2015

AZD7624, an inhaled p38 inhibitor for COPD, attenuates lung and systemic inflammation after LPS Challenge in humans
Source: International Congress 2015 – Advances in the future treatment of COPD
Year: 2015


Toll-like receptor (TLR)-signaling mediates enhanced inflammatory effects in coinfections of viral and bacterial respiratory pathogens in human lung tissue – A new approach to the pathogenesis of COPD exacerbations?
Source: Annual Congress 2011 - Insight into mechanisms of respiratory infections
Year: 2011

COPD airway epithelium secretion attracts and activates neutrophils
Source: International Congress 2014 – Novel evidence relating to respiratory treatment development
Year: 2014

Comprehensive toll-like receptor stimulation and cytokine analysis in precision-cut lung slices
Source: International Congress 2016 – Studies in airway cell biology
Year: 2016

Differential effect of fluticasone on Poly(I:C) induced TSLP secretion by bronchial epithelial cells from asthmatic children
Source: International Congress 2016 – Mechanisms of disease
Year: 2016

Cell therapy by adipose stromal cells affect tracheal responsiveness and inflammatory responses in guinea pigs model of COPD
Source: International Congress 2015 – New models for treating airway diseases
Year: 2015


Activation of the β-catenin pathway by Wnt-1 treatment suppress inflammation in the mouse model of allergic airway disease
Source: International Congress 2015 – Advances in asthma and allergy in animal models
Year: 2015


Aerobic training reverses the inhibition in the expression of glucocorticoid receptors and decreases the Th2 allergic inflammation in asthma model
Source: Annual Congress 2013 –The multiple faces of stress in lung injury
Year: 2013


Anti-inflammatory effects of the novel phosphodiesterase type 4 inhibitor CHF6001 on COPD alveolar macrophages and lung tissue
Source: International Congress 2014 – Novel targets and drugs for asthma and COPD
Year: 2014