Telomere attrition in peripheral blood mononuclear cells of children with alpha-1 antitrypsin deficiency

Francisco Jose Dasi Fernandez (Valencia, Spain), Amparo Escribano, Sara Pastor, Ana Reula, Silvia Castillo, Shirley Camacho, Francisco Sanz, Pilar Codoñer-Franch, Francisco Dasi

Source: International Congress 2015 – Paediatric respiratory physiology
Session: Paediatric respiratory physiology
Session type: Thematic Poster Session
Number: 1255
Disease area: Airway diseases

Congress or journal article abstract

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
Francisco Jose Dasi Fernandez (Valencia, Spain), Amparo Escribano, Sara Pastor, Ana Reula, Silvia Castillo, Shirley Camacho, Francisco Sanz, Pilar Codoñer-Franch, Francisco Dasi. Telomere attrition in peripheral blood mononuclear cells of children with alpha-1 antitrypsin deficiency. Eur Respir J 2015; 46: Suppl. 59, 1255

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
Differentiate late-onset asthma and COPD by CD4+ T memory cells in peripheral blood
Source: International Congress 2015 – Modulating the immune system in COPD and asthma
Year: 2015

Peripheral muscle mitophagy is enhanced in patients with COPD
Source: International Congress 2016 – How the understanding og molecular and genomic crosstalk is helping to diagnose lung disease
Year: 2016

Telomere attrition in circulating white blood cells in COPD relates to lung function and outcomes
Source: International Congress 2014 – Molecular pathogenesis of pulmonary inflammatory diseases (COPD, asthma and ILD)
Year: 2014

Blood T regulatory lymphocytes number is decreased in severe COPD
Source: Annual Congress 2013 –COPD: new markers of diseases
Year: 2013


Regulatory T-lymphocytes in peripheral blood of never smoking patients with COPD
Source: Annual Congress 2013 –Stress responses and T-cell behaviour in the lung
Year: 2013


Lymphocyte senescence in COPD is associated with loss of glucocorticoid receptor expression by cytotoxic/ pro-inflammatory lymphocytes
Source: International Congress 2014 – Effect of cigarette smoke on cell behaviour: cell biology, signalling and senescence
Year: 2014

TNFalpha receptors on monocytes in peripheral blood mononuclear cells culture in active pulmonary tuberculosis
Source: International Congress 2014 – Tuberculosis: diagnosis
Year: 2014

Macrophage migration inhibition factor in peripheral blood and induced sputum in patients with COPD
Source: International Congress 2014 – Basic and translational research in asthma and COPD
Year: 2014

Blood eosinophils as a biomarker in alpha 1 anti trypsin deficiency
Source: International Congress 2015 – Monitoring and phenotyping COPD
Year: 2015

Similar adaptive immune response in COPD patients with and without alpha1 antitrypsin deficiency
Source: Annual Congress 2013 –COPD: new markers of diseases
Year: 2013

Soluble FasL and Fas+ lymphocytes in peripheral blood of non-smoking patients with COPD
Source: International Congress 2014 – Translational studies in COPD
Year: 2014


Deriving type II alveolar cells from pluripotent stem cells to produce a novel model of alpha-1 antitrypsin deficiency pathogenesis
Source: International Congress 2016 – Mechanisms of disease
Year: 2016

Cultured satellite cells as a model for the study of muscle dysfunction in COPD
Source: Annual Congress 2013 –The best posters in exercise testing and physical inactivity
Year: 2013

Endothelial progenitor cells are dysfunctional in smokers and COPD patients due to increased DNA damage and senescence
Source: Annual Congress 2013 –Emerging new targets for the treatment of respiratory diseases
Year: 2013

Changes in the populations of blood T-lymphocytes containing chemokine receptors in non-smoking patients with COPD
Source: Annual Congress 2013 –Stress responses and T-cell behaviour in the lung
Year: 2013


Association between T-regulatory cells blood content and Th2 cells activity in asthma
Source: Annual Congress 2013 –Asthma: new mechanisms and markers
Year: 2013

Neutrophil numbers are decreased in bronchial biopsies from patients with COPD
Source: Annual Congress 2013 –COPD: new markers of diseases
Year: 2013

Identification of Ki67+ ’monocytic’ cells within the lungs
Source: International Congress 2016 – New findings in mucosal immunology
Year: 2016


Cell type specific accessibility of C5aR2 on human blood cells of myeloid origin
Source: International Congress 2016 – Immune responses in the lung
Year: 2016

Activation of immune cell proteasomes in peripheral blood of smokers and COPD patients: implications for therapy
Source: Eur Respir J, 59 (3) 2101798; 10.1183/13993003.01798-2021
Year: 2022