Pleural irrigation trial (PIT): a randomised controlled trial of pleural irrigation with normal saline versus standard care in patients with pleural infection

Hooper Clare E., Edey Anthony J., Wallis Anthony, Clive Amelia O., Morley Anna, White Paul, Medford Andrew R.L., Harvey John E., Darby Mike, Zahan-Evans Natalie, Maskell Nick A.

Source: Eur Respir J 2015; 46: 456-463
Journal Issue: August

Congress or journal article abstractFull text journal articlePDF journal article, handout or slides

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
Hooper Clare E., Edey Anthony J., Wallis Anthony, Clive Amelia O., Morley Anna, White Paul, Medford Andrew R.L., Harvey John E., Darby Mike, Zahan-Evans Natalie, Maskell Nick A.. Pleural irrigation trial (PIT): a randomised controlled trial of pleural irrigation with normal saline versus standard care in patients with pleural infection. Eur Respir J 2015; 46: 456-463

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
LATE-BREAKING ABSTRACT: Pleural irrigation trial (PIT): Standard care versus pleural irrigation, a randomised controlled trial in patients with pleural infection
Source: Annual Congress 2012 - New insights in pneumology - ERS inter-Assemblies late-breaking abstracts
Year: 2012

The second therapeutic intervention in malignant effusion trial (TIME2): A randomised controlled trial to assess the efficacy and safety of patient controlled malignant pleural effusion drainage by indwelling pleural catheter compared to chest drain and talc slurry pleurodesis
Source: Annual Congress 2012 - Biology and treatment of malignant pleural effusions
Year: 2012

Effect of positive airway pressure added to conventional chest physiotherapy in resolution of pleural effusion after drainage: A randomised controlled trial
Source: International Congress 2015 – Effects of rehabilitation, exercise, physical activity, hospitalisation and surgery on different conditions
Year: 2015


A randomised controlled study comparing the outcomes of pleural nurse practitioner (NP) versus doctors trained to perform pleural procedures for management of pleural effusions
Source: Annual Congress 2013 –Interventional pulmonology and pleural diseases
Year: 2013


Randomized parallel arm study to compare intrapleural instillation of streptokinase versus saline wash in loculated empyema thoracis .
Source: Virtual Congress 2021 – Innovation in thoracic surgery
Year: 2021



Results of pre-EDIT; a randomised feasibility trial of Elastance-Directed Intra-pleural catheter or Talc Pleurodesis (EDIT) in malignant pleural effusion
Source: International Congress 2018 – Pleural disease: diagnosis, monitoring and management
Year: 2018



A multicentre study evaluating bleeding risk with intrapleural enzyme therapy in pleural infection (RETROLYSIS)
Source: Virtual Congress 2021 – Novelties in interventional pulmonology
Year: 2021



A randomised controlled study to compare the efficacy of closed pleural biopsy and medical thoracoscopic pleural biopsy in undiagnosed exudative pleural effusion
Source: Annual Congress 2011 - From outside to inside: access to the pleura
Year: 2011

Talcage by medical thoracoscopy for primary spontaneous pneumothorax is more cost-effective than drainage: a randomised study
Source: Eur Respir J 2002; 20: 1003-1009
Year: 2002



Effectiveness of a respiratory physiotherapy program on pleural effusion: A randomized controlled trial
Source: Annual Congress 2013 –Rehabilitation, exercise and adjunct physiotherapy techniques in different respiratory conditions
Year: 2013

Randomised trial of indwelling pleural catheters for refractory transudative pleural effusions
Source: Eur Respir J, 59 (2) 2101362; 10.1183/13993003.01362-2021
Year: 2022



Bacterial culture results in the first 200 patients randomized in the MRC/BTS multicentre intra-pleural streptokinase trial in empyema (MIST - ICTN 39138989)
Source: Eur Respir J 2001; 18: Suppl. 33, 140s
Year: 2001

Intrapleural streptokinase for empyema and complicated parapneumonic effusions: a randomised controlled trial
Source: Annual Congress 2004 - New diagnostic and therapeutic applications in bronchoscopy and thoracoscopy
Year: 2004


A double-blind trial of hyperosmolar saline as an adjunt to phsiotherapy in patients with bronchiectasis
Source: Eur Respir J 2001; 18: Suppl. 33, 484s
Year: 2001

Role of pleural irrigation with normal saline versus streptokinase in complicated pleural effusions.
Source: International Congress 2019 – Interventional pulmonology: current pleural practice
Year: 2019


Prospective randomised trial of 'blind' Abram's pleural biopsies versus CT guided cutting needle biopsies in cytology negative undiagnosed pleural effusions
Source: Eur Respir J 2002; 20: Suppl. 38, 605s
Year: 2002

External assessment and validation of the RAPID score using an international multicentre pleural infection cohort treated with intrapleural fibrinolytics
Source: Virtual Congress 2021 – Respiratory infections and bronchiectasis outcomes
Year: 2021



Thoracic Ultrasound for guiding pleurodesis in malignant pleural effusion: a randomised trial
Source: Virtual Congress 2021 – Thoracic ultrasound: future applications and current evidence
Year: 2021



The effects of T-PEP on ventilation lung scan in patients with bronchiectasis: Protocol for a randomized controlled trial
Source: Annual Congress 2010 - Respiratory muscle function and training in acute and chronic respiratory disease
Year: 2010