Fibroblast-derived non-canonical WNT ligands contribute to attenuated alveolar epithelial repair in COPD

H. A. Baarsma, J. Boczkowski, A. O. Yildirim, M. Königshoff (Munich, Germany; Creteil (Paris), France)

Source: International Congress 2014 – Mechanisms of COPD: proteases and a whole lot more
Session: Mechanisms of COPD: proteases and a whole lot more
Session type: Poster Discussion
Number: 1835
Disease area: Airway diseases

Congress or journal article abstract

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
H. A. Baarsma, J. Boczkowski, A. O. Yildirim, M. Königshoff (Munich, Germany; Creteil (Paris), France). Fibroblast-derived non-canonical WNT ligands contribute to attenuated alveolar epithelial repair in COPD. Eur Respir J 2014; 44: Suppl. 58, 1835

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
R-spondins induce canonical Wnt signaling in lung epithelial cells
Source: International Congress 2014 – Mechanisms of COPD: proteases and a whole lot more
Year: 2014

Impact of Wnt ligand secretion on cellular phenotypes in pulmonary fibrosis
Source: International Congress 2014 – New and old players in fibrotic lung disease
Year: 2014

Accelerating lung epithelial cell senescence in reduced CARM1 mice enhances elastase-induced emphysema
Source: International Congress 2014 – Mechanisms of COPD: proteases and a whole lot more
Year: 2014


Identification of novel proteins involved in beta-catenin dependent alveolar epithelial trans-differentiation
Source: International Congress 2014 – New and old players in fibrotic lung disease
Year: 2014

Matriptase triggers pleiotropic functional responses in normal human lung fibroblasts (NHLF): Potential relevance in pathophysiology
Source: International Congress 2014 – Lung cell biology in injury and repair
Year: 2014

Ventilator-induced lung injury induces a positive signalling feedback loop between Nrf2 and amphiregulin
Source: International Congress 2014 – Acute lung injury: hitting the barriers
Year: 2014

Abnormal respiratory epithelial repair in chronic obstructive pulmonary disease
Source: International Congress 2014 – Mechanisms of COPD and inhalation injury
Year: 2014


Reduction of high mobility group nucleosome binding domain-5 protein promotes the development of emphysema
Source: International Congress 2014 – Mechanisms of COPD: proteases and a whole lot more
Year: 2014

Role of chronic exposure to cigarette smoke on Oct-4/CD146 imbalance in human bronchial epithelial cells
Source: International Congress 2014 – Mechanisms of COPD: proteases and a whole lot more
Year: 2014

Aberrant intracellular expression of laminin alpha-2 and -5 in bronchiolar epithelium of COPD patients
Source: International Congress 2014 – Mechanisms of COPD and inhalation injury
Year: 2014

Gene expression changes of Wnt signalling components during alveolar epithelial transdifferentiation
Source: International Congress 2014 – Acute lung injury: hitting the barriers
Year: 2014

Differential function of IL-17A in cigarette smoke induced lung damage
Source: International Congress 2014 – Mechanisms of COPD: proteases and a whole lot more
Year: 2014

Injury and repair responses of parenchymal fibroblasts in advanced chronic obstructive pulmonary disease
Source: International Congress 2014 – Mechanisms of COPD: proteases and a whole lot more
Year: 2014

Rapid activation of pulmonary endothelial cells during high stretch ventilation in vivo
Source: International Congress 2014 – Acute lung injury: hitting the barriers
Year: 2014



Metalloproteases gene expression and remodeling of lung parenchyma fibers during the progression of elastase induced emphysema
Source: International Congress 2014 – Mechanisms of COPD and inhalation injury
Year: 2014


Wnt-heparan sulfate proteoglycan interaction in fibrotic lung disease
Source: International Congress 2014 – New and old players in fibrotic lung disease
Year: 2014

Non-canonical WNT-5A signaling attenuates endogenous lung repair in COPD
Source: International Congress 2016 – New signalling pathways in COPD
Year: 2016

Functional and molecular disparities between mesenchymal stem cells from various pulmonary disorders
Source: International Congress 2014 – Pulmonary fibrosis: receptors, signalling pathways and mesenchymal cells
Year: 2014



Smoking alters alpha1-antitrypsin in alveolar macrophages possibly promoting misfolding
Source: International Congress 2014 – New studies into pulmonary proteases and antiproteases
Year: 2014

LSC 2014 abstract - The role of the formyl peptide receptor in the development of pulmonary fibrosis
Source: International Congress 2014 – Pulmonary fibrosis: receptors, signalling pathways and mesenchymal cells
Year: 2014