Azithromycin augments rhinovirus-induced expression of IFNbeta and IFNλ1 in asthmatic bronchial epithelial cells by up-regulating RIG-I like receptors

M. Menzel, H. Akbarshahi, L. Bjermer, L. Uller (Lund, Sweden)

Source: International Congress 2014 – Novel evidence relating to respiratory treatment development
Session: Novel evidence relating to respiratory treatment development
Session type: Thematic Poster Session
Number: 963
Disease area: Airway diseases

Congress or journal article abstract

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
M. Menzel, H. Akbarshahi, L. Bjermer, L. Uller (Lund, Sweden). Azithromycin augments rhinovirus-induced expression of IFNbeta and IFNλ1 in asthmatic bronchial epithelial cells by up-regulating RIG-I like receptors. Eur Respir J 2014; 44: Suppl. 58, 963

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
TNF-a induces cPLA2 expression via Jak2/PDGFR-dependent Elk-1/p300 activation in human lung epithelial cells
Source: International Congress 2014 – Mechanistic studies of the airway epithelium
Year: 2014


LSC 2014 abstract - Azithromycin lowers mucin production by increasing FOXA2 expression in an IL-13-induced MUC5AC expression model in human bronchial epithelial cells
Source: International Congress 2014 – Mechanistic studies of the airway epithelium
Year: 2014


Human mast cells and type 2 innate lymphoid cells activate gene expression and mucus composition in human bronchial epithelial cells via IL-13
Source: International Congress 2014 – Mechanistic studies of the airway epithelium
Year: 2014

Enhanced inflammatory gene expression in bronchial epithelial cells from asthmatic patients: Attenuation by a Brd4 mimic
Source: International Congress 2014 – Novel targets and drugs for asthma and COPD
Year: 2014


Interleukin-22 downregulates double-stranded RNA-induced expression of B7-H1/PD-L1 on airway epithelial cells
Source: International Congress 2014 – Mechanistic studies of the airway epithelium
Year: 2014


Inhibition of IRAK4 suppresses chemokine release from human bronchial epithelial cells
Source: Annual Congress 2013 –Molecular biology: state-of-the-art 2013
Year: 2013

IL-8 and TSLP production as markers of bronchial epithelial cell activation in IL-17A mediated airway inflammation in COPD: Role of tiotropium
Source: Annual Congress 2013 –New insights into epigenetic mechanisms in the lung
Year: 2013

IL-4 induced changes in the Wnt signalling of bronchial epithelial cells
Source: International Congress 2015 – Asthma mechanisms and management
Year: 2015

S100 proteins induce MUC5AC production in airway epithelial cells
Source: International Congress 2014 – Mechanistic studies of the airway epithelium
Year: 2014

Corticosteroid plus long-acting beta2-agonist prevent virus-associated upregulation of B7-H1/PD-L1 on airway epithelium
Source: Annual Congress 2013 –Macrophages, mononuclear cells and viral infection
Year: 2013


In vivo effects of corticosteroid plus long-acting beta2-agonist on the expression of B7-H1/PD-L1 in double-stranded RNA-induced lung inflammation
Source: International Congress 2014 – Animal models: asthma, COPD and beyond
Year: 2014


COPD airway epithelium secretion attracts and activates neutrophils
Source: International Congress 2014 – Novel evidence relating to respiratory treatment development
Year: 2014

Interleukin-17A induces glucocorticoid insensitivity in human bronchial epithelial cells
Source: Eur Respir J 2012; 39: 439-445
Year: 2012



Attenuated cytokine response and enhanced toll-like receptor expression by budesonide in bronchial epithelial cells
Source: Eur Respir J 2006; 28: Suppl. 50, 101s
Year: 2006

Glucocorticoids and indacaterol regulated gene expressions profiling in human bronchial epithelial cells
Source: Annual Congress 2013 –Preclinical models for the development of new drugs for respiratory diseases
Year: 2013

microRNA-mediated inhibition of IL-8 production from cystic fibrosis bronchial epithelial cells
Source: Annual Congress 2013 –Cystic fibrosis: basic and applied science
Year: 2013

Inhibitors of apoptosis proteins in asthmatic airway inflammation
Source: Annual Congress 2013 –Asthma: new mechanisms and markers
Year: 2013


Downregulation of IL-27 bronchial epithelial expression by heat-shock protein-60
Source: Annual Congress 2013 –Systemic and airway biomarkers in respiratory diseases
Year: 2013

Differential effect of fluticasone on Poly(I:C) induced TSLP secretion by bronchial epithelial cells from asthmatic children
Source: International Congress 2016 – Mechanisms of disease
Year: 2016