Abnormal abundance of senescent fibroblasts in the tumor stroma of non-small cell lung cancer patients

R. Lugo, M. Puig, A. Giménez, R. Galgoczy, S. Genís, J. Ramírez, P. Gascón, N. Reguart, J. Alcaraz (Barcelona, Spain)

Source: Annual Congress 2013 –Pathogenesis and risk of lung cancer
Session: Pathogenesis and risk of lung cancer
Session type: Thematic Poster Session
Number: 4520
Disease area: Thoracic oncology

Congress or journal article abstract

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
R. Lugo, M. Puig, A. Giménez, R. Galgoczy, S. Genís, J. Ramírez, P. Gascón, N. Reguart, J. Alcaraz (Barcelona, Spain). Abnormal abundance of senescent fibroblasts in the tumor stroma of non-small cell lung cancer patients. Eur Respir J 2013; 42: Suppl. 57, 4520

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
Significance of expression of TGF-β in pulmonary metastasis in non-small cell lung cancer tissues
Source: International Congress 2015 – Lung cancer: prognostic factors and features of oncogene-driven tumours
Year: 2015

Simultaneous EGFR and VEGF alterations in non-small cell lung carcinoma based on tissue microarrays
Source: International Congress 2014 – Pathology and prognostic factors of thoracic tumours
Year: 2014

The influence of erythropoietin on growth and survival in non-small cell lung cancer cell lines
Source: International Congress 2015 – Cell biology of lung cancer and new biomarkers
Year: 2015


CD33+CD14-CD11b+CD66b+CD15+VEGFR-1hi myeloid derived suppressor cells and their clinical relevance in non-small cell lung cancer
Source: International Congress 2014 – Biology and pathology of thoracic tumours
Year: 2014

Molecular signatures of non-small cell lung cancer (NSCLC) obtained from gene expression profiling of the benign bronchial mucosa of smokers with and without NSCLC
Source: Annual Congress 2013 –Biology and molecular pathology of lung cancer
Year: 2013

Aromatase inhibition alters the mechanical properties of non small-cell lung cancer cells affecting cell movement
Source: Annual Congress 2013 –Basic research on lung cancer
Year: 2013


Expression analysis of miR-21 in Bulgarian patients with non-small cell lung cancer
Source: International Congress 2016 – Prognostic variables in lung cancer I
Year: 2016


A tissue microarray analysis on the role of chromosome 7 multiplication regarding the EGFR expression in non-small cell lung carcinomas
Source: International Congress 2016 – Molecular targets in pulmonary disease
Year: 2016

The effect of surgical specimen-derived phosphorus and lead concentrations in non-small cell lung cancer patients on disease course
Source: International Congress 2016 – Prognostic variables in lung cancer I
Year: 2016

Role of hypoxia in epithelial-to-mesenchymal transition (EMT) in non-small cell lung cancer (NSCLC)
Source: International Congress 2014 – Basic and translational research in lung cancer and non-neoplastic pulmonary diseases
Year: 2014

beta-F1-ATPase expression as a prognostic factor for resected non-small cell lung cancer
Source: Annual Congress 2013 –Prognostic factors and subtyping of lung cancer
Year: 2013

Significance of EGFR expression patterns in patients with non-small cell lung cancer – Evaluation on protein- and/or gene level?
Source: International Congress 2014 – Pathology and prognostic factors of thoracic tumours
Year: 2014


Epidermal growth factor receptor and related biomarkers evaluated by immunohistochemistry in patients with resected non-small cell lung cancer
Source: Annual Congress 2013 –Prognostic factors and subtyping of lung cancer
Year: 2013


Prognostic value study of lung cancer molecular markers and value of mitochondrial activity in resected non-small cell lung cancer
Source: Annual Congress 2013 –Prognostic factors and subtyping of lung cancer
Year: 2013

Prognostic impact of secondary malignancies in non-small cell lung cancer (NSCLC)
Source: International Congress 2015 – Lung cancer: prognostic factors and features of oncogene-driven tumours
Year: 2015

EGFRmutations are associated with higher brain metastasis radio-sensitivity than KRAS mutations or wild type EGFR in non-small cell lung cancer patients (NSCLC)
Source: International Congress 2014 – Therapy of thoracic tumours: clinical trials and case series
Year: 2014

Screening for intracerebral metastasis in radically treated non-small cell lung cancer patients
Source: International Congress 2016 – Lung cancer: therapeutic modalities, re-staging, and follow-up
Year: 2016


Proapoptotic effects of PAI-1 protein on lung and prostate cancer cells
Source: Annual Congress 2013 –Basic research on lung cancer
Year: 2013


Adenylate cyclase-associated protein 1 is associated with metastasis of non-small cell lung cancer especially in brain metastasis patients and promotes the lung cancer cell proliferation and migration in vitro as well as its growth and metastasis in vivo by the signaling pathways of limk1-cofilin
Source: International Congress 2015 – New frontiers in biomedical research on thoracic tumours
Year: 2015


Prognostic factors in non-small cell lung cancer
Source: International Congress 2015 – Diagnosis and therapy of lung cancer
Year: 2015