IL-10 and IL-1ra mediates OVA-induced Th2 airway allergic response at short and long-term

R. A. Silva, F. M. Almeida, C. R. Olivo, B. M. Saraiva, A. Perini, M. A. Martins, C. R. F. Carvalho (Sao Paulo, Brazil)

Source: Annual Congress 2013 –The role of hormones and cytokines in lung injury
Session: The role of hormones and cytokines in lung injury
Session type: Thematic Poster Session
Number: 3931
Disease area: Airway diseases

Congress or journal article abstractE-poster

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
R. A. Silva, F. M. Almeida, C. R. Olivo, B. M. Saraiva, A. Perini, M. A. Martins, C. R. F. Carvalho (Sao Paulo, Brazil). IL-10 and IL-1ra mediates OVA-induced Th2 airway allergic response at short and long-term. Eur Respir J 2013; 42: Suppl. 57, 3931

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
Aerobic training reverses the inhibition in the expression of glucocorticoid receptors and decreases the Th2 allergic inflammation in asthma model
Source: Annual Congress 2013 –The multiple faces of stress in lung injury
Year: 2013


Aerobic exercise reduces pulmonary inflammation in diet-induced obesity in a HDM model of asthma through adipokines, IL-10, IL-17 and IL-23 signaling
Source: International Congress 2015 – New insights into exercise and muscle performance
Year: 2015


Interleukin-33 and Th2 cytokines correlate in acute asthma
Source: International Congress 2016 – Clinical and molecular studies in asthma
Year: 2016

Regulatory role of antigen-induced IL-10, produced by Tr1 cells, in airway neutrophilia in a murine model for asthma
Source: Annual Congress 2012 - Asthma: mechanisms of airway inflammation
Year: 2012


Montelukast reduces Th2 type cytokines in induced sputum in mild asthma
Source: Eur Respir J 2002; 20: Suppl. 38, 111s
Year: 2002

IL-37 requires IL18Rα and SIGIRR to diminish experimental allergic airway inflammation in mice
Source: International Congress 2015 – Animal studies of asthma and other inflammatory conditions
Year: 2015

Interleukin (IL-13) modulates allergen-induced airway hyperresponsiveness by a pathway independent of IL-5 or eotaxin in mice
Source: Eur Respir J 2003; 22: Suppl. 45, 194s
Year: 2003

Transgenic mice overexpressing IL-18 display increased IL-13 in the airways but no changes of the airway hyperresponsiveness in a murine model of late-phase asthma: evidence for a dual role of IL-18 on mucosal Th1/Th2 responses
Source: Eur Respir J 2002; 20: Suppl. 38, 1s
Year: 2002

The inflammation and the airway hyperresponsiveness in allergic asthma is inhibited by IL-10 dependent mechanism
Source: Annual Congress 2007 - Mouse models of allergic airway inflammation
Year: 2007


Inhibition of the asthmatic allergen challenge response by the CRTH2 antagonist OC000459
Source: Eur Respir J 2013; 41: 46-52
Year: 2013



Modulation of ozone-induced airway hyperresponsiveness and inflammation by interleukin-13
Source: Eur Respir J 2008; 32: 571-578
Year: 2008



High-level expression of PD-L1 by DC suppresses airway inflammation in OVA-induced allergic asthma
Source: Annual Congress 2010 - Animal models of asthma and lung inflammation
Year: 2010

Imiquimod attenuate airway inflammation and decrease the expression of TARC in allergic asthmatic mice
Source: Eur Respir J 2006; 28: Suppl. 50, 224s
Year: 2006

Elevated IL-10 level but not cysteinyl leukotrienes (CysLT) release from leukocytes in vitro correlates with good response to treatment with montelukast in asthmatic patients
Source: International Congress 2014 – Asthma and COPD management
Year: 2014


Late Breaking Abstract - IL-33 drives influenza-induced exacerbations of asthma by halting anti-viral and Th1 responses
Source: International Congress 2017 – Animal models of asthma and allergies
Year: 2017

Farm dust decreases Th2 driven allergic airway inflammation in mice: A role for airway TLR2 and TLR4?
Source: Annual Congress 2011 - T-cell subsets
Year: 2011


Aerobic exercise reduces asthma phenotype by inhibition of JAK2, SOCS3 and STAT6 in airway epithelium and in peribronchial leukocytes
Source: International Congress 2016 – Latest insights into functional capacity and muscle weakness in chronic lung diseases
Year: 2016


Preventative administration of IL-27 improves airway inflammation of ovalbumin –induced asthma mice model via both STAT1 and GADD45γ/p38MAPK pathways
Source: International Congress 2016 – Pharmacological intervention in humans and murine models of asthma
Year: 2016


Chronic inflammation in asthma
Source: ISSN=1025-448x, ISBN=1-904097-26-x, page=126
Year: 2003

Caspase-1 induces upstream Th2-cytokines IL-33 and TSLP and eosinophilia at viral induced asthma exacerbations
Source: International Congress 2016 – Asthma: mechanisms and biomarkers that promote clinical understanding
Year: 2016