LSC 2013 abstract - NADPH oxidase isoform 2 (NOX2) is expressed in alveolar macrophages of emphysematous patients and prevents elastase-induced emphysema through the involvement of MMP9/TIMP1 gene expression

J. C. Pache, Y. Donati, C. Deffert, K. H. Krause, C. Barazzone-Argiroffo, S. Carnesecchi (Geneva, Switzerland)

Source: Annual Congress 2013 –Translational studies in chronic repair and remodelling in the lung

Session: Translational studies in chronic repair and remodelling in the lung
Session type: Oral Presentation
Number: 3324

Disease area: Airway diseases

Rating:

You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
J. C. Pache, Y. Donati, C. Deffert, K. H. Krause, C. Barazzone-Argiroffo, S. Carnesecchi (Geneva, Switzerland). LSC 2013 abstract - NADPH oxidase isoform 2 (NOX2) is expressed in alveolar macrophages of emphysematous patients and prevents elastase-induced emphysema through the involvement of MMP9/TIMP1 gene expression. Eur Respir J 2013; 42: Suppl. 57, 3324

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.

You must Login to comment this presentation.

Related content which might interest you:

NADPH oxidase isoform 1 is expressed in lung tissue of ARDS patients and decreases hyperoxia-induced ROS production and cell death in pulmonary type II epithelial cells Source: Annual Congress 2011 - Barrier functions in sepsis and acute lung injury Year: 2011
Activation of membrane nadph oxidase in idiopathic pulmonary fibrosis (IPF) fibroblasts Source: Annual Congress 2007 - Recent advances in the understanding of lung injury and repair Year: 2007
IL-4/13-induced up-regulation of METEORIN-LIKE (ML) in alveolar macrophages promotes epithelial CCR3 expression Source: International Congress 2017 – Asthma and allergy: from the bench to the bedside Year: 2017
Differential expression of the S1P transporter, Spinster homologue 2 (Spns2), in airway epithelial cells and macrophages may drive defective macrophage function in COPD Source: International Congress 2017 – Cigarette smoke and particulate matter: basic science and clinical aspects Year: 2017
LSC 2013 abstract - The role of inducible nitric oxide synthase (iNOS) for the remodeling of alveolar septa in surfactant protein D deficient mice Source: Annual Congress 2013 –Idiopathic pulmonary fibrosis: pathogenesis Year: 2013
Erythropoietin (EPO) inhibits the immunohistochemical expression of lysyl oxidase (LOX) in bleomycin (BLM)-induced pulmonary fibrosis (PF) in rats Source: International Congress 2015 – Pulmonary fibrosis: mechanisms of disease Year: 2015
NADPH oxidase 4 deficiency protects from bleomycin-induced epithelial cell death and pulmonary fibrosis Source: Annual Congress 2010 - New insights into reactive oxygen species Year: 2010
LSC - 2018 - Collagen-producing macrophages can mediate lung fibrosis throughFra-2/AP-1 expression Source: International Congress 2018 – New insights in the signalling pathways that underlie IPF pathophysiology Year: 2018
NADPH oxidase 4 signaling in a ventilator-induced lung injury mice model Source: Virtual Congress 2020 – Experimental and laboratory studies in intensive care unit medicine Year: 2020
Hypoxia-dependent regulation of non-phagocytic NADPH oxidase NOX4 in the pulmonary vasculature Source: Eur Respir J 2007; 30: Suppl. 51, 56s Year: 2007
Fc gamma receptor III (FcγRIII) expression by alveolar macrophages is up-regulated by silica particles but is dispensable for silica-induced alveolitis in mice Source: Eur Respir J 2007; 30: Suppl. 51, 368s Year: 2007
Kaempferol-induced HO-1 expression attenuated inflammation in human pulmonary alveolar epithelial cells Source: International Congress 2017 – Therapeutic approaches in lung disease Year: 2017
Decreased expression of haem oxygenase-1 by alveolar macrophages in idiopathic pulmonary fibrosis Source: Eur Respir J 2008; 31: 1030-1036 Year: 2008
A neo-epitope of serum lysyl oxidase like 2 (LOXL2) generated during enzyme maturation is elevated in cancer and idiopathic pulmonary disease Source: International Congress 2017 – Techniques in biomarker selection Year: 2017
LSC 2013 abstract - Mechanisms regulating enhanced alphavbeta6 expression in pulmonary fibrosis Source: Annual Congress 2013 –Growth factors at the crossroads of acute and chronic inflammation Year: 2013
Production of matrix metalloprotease-9 (MMP-9) by alveolar macrophages (AMs) from smokers: effect of corticosteroids and phosphodiesterase inhibition Source: Eur Respir J 2001; 18: Suppl. 33, 34s Year: 2001
Enhanced expression of Fas ligand (FasL) in fibrotic interstitial lung diseases (ILDs). The possible role of membrane-bound FasL form Source: Annual Congress 2011 - Genetic and molecular background in pulmonary fibrosis Year: 2011
Human macrophage elastase (MMP-12) expression in human emphysematous lungs: role in extracellular matrix remodelling in chronic obstructive pulmonary diseases (COPD) Source: Eur Respir J 2001; 18: Suppl. 33, 501s Year: 2001
Decreased mRNA and protein expression of peroxiredoxin (PRDX6) in the COPD lung Source: Eur Respir J 2004; 24: Suppl. 48, 320s Year: 2004
TGF-beta-dependent inhibitor of DNA protein (Id) expression in lung fibrosis Source: Eur Respir J 2006; 28: Suppl. 50, 521s Year: 2006