Involvement of 5-lipoxygenase (5-LO) pathway in eosinophil chemotaxis to acetylsalicylic acid (ASA) in aspirin-sensitive and healthy non-allergic subjects Source: Eur Respir J 2002; 20: Suppl. 38, 382s Year: 2002
Eosinophils chemotaxis to acetylsalicylic acid (ASA) is inhibited in aspirin-sensitive (ASA-S) asthmatics - possible role for lymphocyte involvement Source: Eur Respir J 2001; 18: Suppl. 33, 406s Year: 2001
Increased release of cysteinyl-leukotrienes in ex vivo stimulated sputum cells from subjects with aspirin-intolerant asthma Source: Annual Congress 2007 - Noninvasive evaluation of airway diseases Year: 2007
Assessment of in vivo 5-lipoxygenase (5-LO) activity in nonatopic and atopic subjects with or without asthma: effects of treatment with the 5-LO inhibitor zileuton Source: Eur Respir J 2003; 22: Suppl. 45, 101s Year: 2003
Dual inhibition of thromboxane synthase and 5-lipoxygenase, potentially significant mechanism for the treatment of asthma Source: Eur Respir J 2001; 18: Suppl. 33, 264s Year: 2001
Aspirin significantly decreases urinary leukotriene E4 concentration in aspirin-tolerant asthma patients who show hyperleukotrienuria in stable condition Source: Annual Congress 2007 - New mechanisms in the pathogenesis of asthma and allergy Year: 2007
Imbalance of anti-inflammatory (resolving D1) and pro-inflammatory (leukotrien B4) arachidonic acid products in exhaled breath condensate of severe refractory asthma. Source: International Congress 2017 – Airway disease and exacerbations Year: 2017
Quantitative assessment of cysteinyl leukotrienes in human sputum during the allergen-induced asthmatic response and the effect of GSK2190915, a 5-lipoxygenase activating protein (FLAP) inhibitor Source: Annual Congress 2011 - Diagnosis and treatment of inflammatory respiratory diseases Year: 2011
Clinical and biochemical differences between patients with aspirin-induced asthma/rhinitis Source: Annual Congress 2005 - PG18 - Inter-relationships between upper and lower airway diseases Year: 2005
Do leukotriene antagonists reduce eosinophil numbers in induced sputum from asthmatic patients as a consequence of increased apoptosis induction? Source: Eur Respir J 2002; 20: Suppl. 38, 584s Year: 2002
Erdosteine affects eicosanoid production in asthma and COPD Source: Annual Congress 2008 - Recent advances in the treatment and pathogenesis of asthma Year: 2008
Effects of selective and non-selective cyclooxygenase inhibition on exhaled eicosanoids in COPD Source: Eur Respir J 2004; 24: Suppl. 48, 578s Year: 2004
Higher expression of lipoxygenase and cyclooxygenase pathways in bronchial than alveolar lavage from allergic asthmatics Source: Virtual Congress 2021 – Clinical features and new biomarkers of asthma, COPD and chronic cough Year: 2021
Inhalation of mannitol, used as a model for exercise-induced bronchoconstriction (EIB), causes release of leukotrienes and a mast cell marker in asthmatic subjects Source: Eur Respir J 2001; 18: Suppl. 33, 102s Year: 2001
Increased leukotriene and lower prostaglandin E2 concentrations in induced sputum of patients with eosinophilic asthma Source: Eur Respir J 2005; 26: Suppl. 49, 733s Year: 2005
Aminoguanidine inhibits bronchial NO production, but not diffusion or alveolar NO in patients with asthma, smokers and healthy volunteers Source: Eur Respir J 2004; 24: Suppl. 48, 577s Year: 2004
Cysteinyl leukotrienes and leukotriene B4 in expired breath condensate in patients with chronic asthma treated with montelukast Source: Eur Respir J 2003; 22: Suppl. 45, 101s Year: 2003
COX-1 driven biosynthesis of PGD2 during activation of human mast cells prevents formation of other prostanoids Source: Virtual Congress 2020 – Novel molecular markers and targets for asthma phenotypes Year: 2020
Induced sputum supernatant eicosanoids during oral aspirin challenge of asthmatic patients with and without aspirin hypersensitivity and healthy controls Source: International Congress 2015 – New insights into lung disease pathogenesis Year: 2015
The effect of GSK2190915, a 5-lipoxygenase activating protein inhibitor, on the early asthmatic response to inhaled allergen Source: Annual Congress 2011 - Asthma management and response Year: 2011