Bradykinin-induced fibroblast proliferation and myofibroblast differentiation via B2 receptor pathway

F. Sabatini, F. Luppi, L. Petecchia, A. Longo, L. Serpero, M. Silvestri, S. Carnevali, L. M. Fabbri, G. A. Rossi, F. L. Ricciardolo (Genoa, Modena, Italy)

Source: Annual Congress 2005 - Airway biology
Session: Airway biology
Session type: Thematic Poster Session
Number: 2234
Disease area: Airway diseases

Congress or journal article abstract

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
F. Sabatini, F. Luppi, L. Petecchia, A. Longo, L. Serpero, M. Silvestri, S. Carnevali, L. M. Fabbri, G. A. Rossi, F. L. Ricciardolo (Genoa, Modena, Italy). Bradykinin-induced fibroblast proliferation and myofibroblast differentiation via B2 receptor pathway. Eur Respir J 2005; 26: Suppl. 49, 2234

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
Bradykinin-induced myofibroblast differentiation and calcium mobilization in airway fibroblast
Source: Eur Respir J 2005; 26: Suppl. 49, 342s
Year: 2005

A549 cell promotes the proliferation and migration of fibroblast through FXR pathway
Source: International Congress 2019 – Biology of lung cancer
Year: 2019

The inducible kinin B1 receptor stimulates human airway fibroblast (Fb) proliferation
Source: Eur Respir J 2004; 24: Suppl. 48, 37s
Year: 2004

Modulation of vascular progenitor cell differentiation by TGFß and endothelin-1 receptor inhibition
Source: Annual Congress 2009 - Pathobiology of pulmonary vascular diseases
Year: 2009


Effect of bradykinin (BK) on human airway fibroblast (Fb) proliferation and myofibroblast (MyoFb) differentiation
Source: Eur Respir J 2004; 24: Suppl. 48, 37s
Year: 2004

In vitro profibrotic effects of rapamycin on basal or TGF-β1 induced primary human lung fibroblast: ECM production and turnover, migration and differentiation
Source: Annual Congress 2012 - Diffuse parenchymal lung disease I
Year: 2012

Molecular mechanisms of the synergy between cysteinyl-leukotrienes and receptor tyrosine kinase growth factors on human bronchial fibroblast proliferation
Source: Eur Respir J 2006; 28: Suppl. 50, 339s
Year: 2006

Molecular mechanisms of the synergy between cysteinyl-leukotrienes and receptor tyrosine kinase growth factors on human bronchial fibroblast proliferation
Source: Eur Respir Rev 2006; 15: 172-174
Year: 2006



Hepatocyte and keratinocyte growth factor (HGF and KGF prevent rat alveolar type II cells from mechanical stretch induced apoptosis – role of phosphoinositide 3-OH kinase
Source: Eur Respir J 2007; 30: Suppl. 51, 292s
Year: 2007

Down-regulation of the P2Y12 purinergic receptor expression on human bronchial epithelial cells by transforming growth factor-beta
Source: Annual Congress 2013 –Cell signalling and inflammation: what's new in 2013?
Year: 2013

Inhibition of VEGF blocks TGF-β1 production through a PI3K/Akt signalling pathway
Source: Eur Respir J 2008; 31: 523-531
Year: 2008



Differential role of EPAC and PKA in the transduction of cAMP-mediated inhibition of human lung fibroblast proliferation and collagen synthesis
Source: Annual Congress 2009 - Pathological remodelling in chronic lung disease: from epithelial-mesenchymal transition to cellular activation
Year: 2009


Interleukin-8 stimulates human airway epithelial cell proliferation through EGFR transactivation
Source: Eur Respir J 2003; 22: Suppl. 45, 561s
Year: 2003

Effects of TGF-beta and budesonide on MAPK phosphorylation, IL-6/IL-11 secretion, and cell proliferation in human lung fibroblasts
Source: Eur Respir J 2006; 28: Suppl. 50, 662s
Year: 2006

Vascular endothelial growth factor induction by PGE2 in human airway smooth muscle cells is mediated by EP2/EP4 receptors and Sp-1 transcription factor binding sites
Source: Eur Respir J 2005; 26: Suppl. 49, 127s
Year: 2005

Effects of endothelin-1 on MAPK activation, IL-6 production and cell proliferation in normal human lung fibroblasts
Source: Eur Respir J 2004; 24: Suppl. 48, 454s
Year: 2004

Notch activity is required for myofibroblast differentiation
Source: International Congress 2019 – Oxidative stress, hypoxia and microbial exposure in the pathogenesis of pulmonary disease
Year: 2019

NGF activation of the TrkA receptor induces airway smooth muscle proliferation
Source: Eur Respir J 2004; 24: Suppl. 48, 218s
Year: 2004

Lipoxin A4 promotes lung epithelial repair whilst inhibiting fibroblast proliferation
Source: ERJ Open Res 2016: 00079-2015
Year: 2016