TGF-beta alters TRPC6 expression and calcium handling via smad2/3 in human airway smooth muscle

D. Wright, Y. Shaifta, V. Snetkov, J. Ward (London, United Kingdom)

Source: Annual Congress 2013 –Airway smooth muscle and cell biology
Session: Airway smooth muscle and cell biology
Session type: Thematic Poster Session
Number: 556
Disease area: Airway diseases

Congress or journal article abstractE-poster

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
D. Wright, Y. Shaifta, V. Snetkov, J. Ward (London, United Kingdom). TGF-beta alters TRPC6 expression and calcium handling via smad2/3 in human airway smooth muscle. Eur Respir J 2013; 42: Suppl. 57, 556

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
FGF-2 modulates human airway smooth muscle contractile protein expression and cell stiffness
Source: Annual Congress 2013 –Airway smooth muscle and cell biology
Year: 2013

MNK-1 inhibition reduces proliferation and CXCL10 in airway smooth muscle cells
Source: Annual Congress 2013 –Airway smooth muscle and cell biology
Year: 2013

WNT-5A and WNT-11 as novel regulators of the contractile airway smooth muscle phenotype
Source: Annual Congress 2013 –Airway smooth muscle and cell biology
Year: 2013


Regulation of actin dynamics by WNT-5A: Implications for human airway smooth muscle contraction
Source: International Congress 2016 – Studies in airway cell biology
Year: 2016


Epac1 and Epac2 regulate airway smooth muscle tone in mice
Source: International Congress 2016 – Translational studies in lung disease
Year: 2016

Eosinophil-induced airway smooth muscle cells remodeling is attenuated by blocking of RGD-binding integrins in asthma
Source: International Congress 2016 – New findings in mucosal immunology
Year: 2016

Airway smooth muscle contractility is increased following coculture with fibrocytes
Source: International Congress 2016 – Mechanisms of disease
Year: 2016

A functional role for WNT-5A in driving airway myocyte proliferation
Source: Annual Congress 2013 –Growth factors at the crossroads of acute and chronic inflammation
Year: 2013


DP2/CRTh2 is expressed by ASM cells in asthma and its inhibition suppresses ASM migration
Source: International Congress 2016 – Mechanisms of disease
Year: 2016

The c-jun N-terminal kinase signaling pathway regulates airway smooth muscle cell proliferation
Source: International Congress 2014 – Cell biology 2014
Year: 2014


p53 dysfunction increased mitochondrial biogenesis and bronchial smooth muscle cell proliferation in asthma
Source: International Congress 2015 – Airway remodelling: recent developments
Year: 2015


Integrins regulate eosinophil adhesion to the airway smooth muscle cells in asthma patients
Source: International Congress 2015 – Asthma mechanisms and management
Year: 2015

IL33 and TNFalpha synergistically enhance store operated Ca2+ entry in cultured human airway smooth muscle cells
Source: Annual Congress 2013 –Preclinical models for the development of new drugs for respiratory diseases
Year: 2013


Link between airway inflammation and remodeling: TNFα induces airway smooth muscle cell proliferation via an ET1/GMCSF/IL6 network
Source: International Congress 2015 – Airway remodelling: recent developments
Year: 2015

Endothelin receptor B protects GM-CSF mRNA from degradation in human airway smooth muscle cells
Source: International Congress 2015 – Immunomodulation: basic science and clinical aspects
Year: 2015

Activation of TRPV4 triggers ATP release and mast cell dependent contraction of airway smooth muscle (ASM)
Source: International Congress 2015 – Novel targets and strategies for the treatment of cough, asthma, rhinosinusitis and COPD
Year: 2015

CCL2 release by airway smooth muscle is increased in asthma and promotes fibrocyte migration
Source: International Congress 2014 – Cell biology 2014
Year: 2014


Targeting ASK1 in preventing airway smooth muscle growth: Implications for airway remodeling in COPD
Source: International Congress 2016 – New findings in mucosal immunology
Year: 2016


Tocotrienol inhibits TGF-beta1-induced human airway smooth muscle cell differentiation
Source: Annual Congress 2013 –Airway smooth muscle and cell biology
Year: 2013


Small-non coding YRNAs can regulate the plasticity of smooth muscle cells
Source: Annual Congress 2013 –Genetics and genomics of lung disease
Year: 2013