The effects of intra-nasally administered anti-inflammatory compounds in a mouse model of acute COPD exacerbations Source: Annual Congress 2013 –Preclinical models for the development of new drugs for respiratory diseases Year: 2013
Prediction of human lung PK for AZD7624, an inhaled P38 inhibitor for the treatment of COPD Source: International Congress 2015 – Novel treatments for cough, asthma, COPD and bronchiectasis Year: 2015
CHI-91040, a novel inhaled p38α inhibitor, counteracts lung inflammation induced by IL-1β in the rat Source: International Congress 2016 – ILD: from the bench to the bedside Year: 2016
The anti-inflammatory effects of PF03715455 and roflumilast on both cellular and tissue inflammation in a mouse model of COPD Source: Annual Congress 2013 –New drugs in respiratory medicine Year: 2013
The combination of TNF-α neutralization and dexamethasone treatment restored the corticosteroid responsiveness in tobacco smoking mice Source: International Congress 2016 – Airway pharmacology: drug targets and mode of action Year: 2016
Efficacy of dexamethasone, roflumilast and azithromycin in a murine cigarette smoke/NTHi infection model Source: International Congress 2016 – Microbiological issues and translational research in respiratory infections Year: 2016
In vivo efficacy of CHF6001, an inhaled PDE4 inhibitor with a wide therapeutic window Source: International Congress 2014 – Animal models in respiratory drug development Year: 2014
Pharmacological profile and efficacy of GLPG1690, a novel ATX inhibitor for COPD treatment Source: International Congress 2015 – New targets and modalities for the treatment of asthma and COPD Year: 2015
Effects of acute hypochlorite exposure in OVA-sensitized and challenged mice Source: International Congress 2015 – Occupational and environmental effects: in vitro and animal models Year: 2015
Effects of tobacco smoke and poly IC, alone and in combination, on mouse lung pathology Source: Annual Congress 2013 –Preclinical models for the development of new drugs for respiratory diseases Year: 2013
The anti-inflammatory effects of eucalyptol in a mouse model of LPS-induced pulmonary inflammation are mediated by TRPM8 Source: International Congress 2016 – Therapeutic horizons: novel targets and pharmacological models Year: 2016
RP6503, a novel and selective PI3K δ/gamma inhibitor, potentiates the effect of steroids in pre-clinical models of COPD Source: International Congress 2014 – New treatments for cough, asthma, COPD and ILDs Year: 2014
Pre-clinical to clinical potency of AZD7624 in LPS induced TNFa response Source: International Congress 2015 – New targets and modalities for the treatment of asthma and COPD Year: 2015
Effect of MSC treatment on LPS-induced inflammation, emphysema and atherosclerosis in E3L mice Source: International Congress 2015 – The multiple facets of stem and progenitor cells in lung health and disease Year: 2015
Effect of the combination of doxofylline and montelukast on LPS-induced leukocyte migration to the lung Source: International Congress 2014 – Animal models in respiratory drug development Year: 2014
Effects of phosphoinositide-3-kinase inhibitors on steroid-insensitive airway inflammation in poly(I:C) and allergen challenged mice Source: International Congress 2016 – Novel mechanisms and treatment modalities in asthma Year: 2016
The effects of clinically relevant reference agents in a mouse model of severe asthma Source: International Congress 2015 – Advances in the future treatment of severe asthma Year: 2015
Implication of interleukin-10 in the development of COPD induced by cigarette smoke exposure in mice Source: Annual Congress 2013 –COPD: experimental biology Year: 2013
Pharmacokinetics of selective PI3Kδ inhibitors after intratracheal instillation in mice Source: International Congress 2015 – New targets and modalities for the treatment of asthma and COPD Year: 2015
Safety, tolerability, pharmacokinetics (PK) and pharmacodynamics (PD) of single (SD) and repeat (RD) inhaled doses of a novel phosphoinositide 3-kinase δ inhibitor (PI3Kδ), GSK2269557, administered to healthy smokers Source: International Congress 2014 – New drugs for asthma, COPD and pulmonary fibrosis Year: 2014