MMPs are regulatory enzymes in pathways of inflammatory disorders, tissue injury, malignancies and remodelling of the lung Source: Eur Respir J 2011; 37: 12-14 Year: 2011
Tezepelumab decreases matrix remodelling and inflammatory pathways in patients with asthma Source: International Congress 2019 – ALERT: Abstracts Leading to Evolution in Respiratory Medicine Trials: Asthma Year: 2019
Effect of genetic polymorphisms of some cytokines and xenobiotic-metabolizing enzymes on the lung function in patients with COPD Source: Annual Congress 2012 - Recent progress in mechanisms and diagnostics of COPD and asthma Year: 2012
Genomic markers of retinoid response in COPDe: R667 modulates genes associated inflammation and energy metabolism Source: Annual Congress 2007 - Novel genetic markers in pathology Year: 2007
The extracellular matrix of the lung: composition, homeostasis, and regulation by growth factors and cytokines Source: Annual Congress 2009 - Pressure for plasticity: the pulmonary interstitium in the diseased lung Year: 2009
Effects of antioxidant enzyme polymorphisms on ozone-induced lung function changes Source: Eur Respir J 2007; 30: 677-683 Year: 2007
Composition of the cellular matrix, nutrition, and hypoxia modulate the secretion and activation of collagenases and their inhibitors in human lung cells Source: Eur Respir J 2001; 18: Suppl. 33, 244s Year: 2001
Nrf2-regulated chaperon-mediated autophagy is involved in apoptosis modulation in COPD pathogenesis. Source: Virtual Congress 2020 – Cellular stress in respiratory diseases Year: 2020
PGAM5 acts as a key mediator of lung fibrosis by disrupting mitochondrial homeostasis Source: International Congress 2019 – Extracellular matrix formation and remodelling in physiology and disease Year: 2019
Profiling of airway epithelial proteome reveals sex differences in early stage COPD linked to xenobiotic metabolism and ER stress Source: Virtual Congress 2020 – Novel methods, diagnostics and biomarkers of chronic lung diseases Year: 2020
Modulation of oxidative stress pathway by arginase inhibition: Evaluation in an animal model of chronic pulmonary inflammation Source: Annual Congress 2010 - Regulation of airway pharmacology Year: 2010
PP208 – SRC family kinases modulate molecular pathways associated with mitochondrial dysfunction in idiopathic pulmonary fibrosis Source: ERS Lung Science Conference 2021 Year: 2021
Extracellular vesicles and their role in lung homeostasis and disease Source: International Congress 2018 – Cross-talk in the lung microenvironment: implications for chronic lung disease Year: 2018
Heterozygous SOD2 deletion deteriorated chronic intermittent hypoxia-induced lung inflammation and vascular remodeling through mtROS-NLRP3 signaling pathway Source: Virtual Congress 2020 – New insights into sleep apnoea: from diagnosis to treatment Year: 2020
Eosinophils contribute to extracellular matrix remodeling by enhancing pulmonary fibroblasts proliferation, differentiation and extracellular matrix proteins production in asthma Source: International Congress 2018 – Identification of therapeutic targets for asthma Year: 2018
Multifaceted mechanisms in COPD: inflammation, immunity, and tissue repair and destruction Source: Eur Respir J 2008; 31: 1334-1356 Year: 2008
PP216 – Glucocorticoids exacerbate TGFß1 mediated fibrotic signalling in lung fibroblasts by inhibition of metalloproteinase expression and activity Source: ERS Lung Science Conference 2021 Year: 2021
A potential role for extracellular matrix proteins in lung ageing in COPD Source: International Congress 2016 – How the understanding og molecular and genomic crosstalk is helping to diagnose lung disease Year: 2016
Physical stress modulates distal lung tissue mechanics, inflammation and remodelling associated to iNOS and oxidative stress activation Source: Annual Congress 2008 - Pathophysiology of respiratory diseases Year: 2008