e-learning
resources
Vienna 2012
Wednesday, 05.09.2012
Pulmonary circulation: basic mechanisms
Login
Search all ERS
e-learning
resources
Disease Areas
Airways Diseases
Interstitial Lung Diseases
Respiratory Critical Care
Respiratory Infections
Paediatric Respiratory Diseases
Pulmonary Vascular Diseases
Sleep and Breathing Disorders
Thoracic Oncology
Events
International Congress
Courses
Webinars
Conferences
Research Seminars
Journal Clubs
Publications
Breathe
Monograph
ERJ
ERJ Open Research
ERR
European Lung White Book
Handbook Series
Guidelines
All ERS guidelines
e-learning
CME Online
Case reports
Short Videos
SpirXpert
Procedure Videos
CME tests
Reference Database of Respiratory Sounds
Radiology Image Challenge
Brief tobacco interventions
EU Projects
VALUE-Dx
ERN-LUNG
ECRAID
UNITE4TB
Disease Areas
Events
Publications
Guidelines
e-learning
EU Projects
Login
Search
Reduction in serotonin signaling via TPH1 inhibition attenuates the progression of PAH in mice with genetic ablation of endothelial BMPR-II
L. Ciuclan, N. Duggan, M. Hussey, R. Good, O. Bonneau, D. Rowlands, V. Burton, G. Jarai, J. Westwick, M. Thomas (Horsham, United Kingdom)
Source:
Annual Congress 2012 - Pulmonary circulation: basic mechanisms
Session:
Pulmonary circulation: basic mechanisms
Session type:
Oral Presentation
Number:
4554
Disease area:
Pulmonary vascular diseases
Rating:
You must
login
to grade this presentation.
Share or cite this content
Citations should be made in the following way:
L. Ciuclan, N. Duggan, M. Hussey, R. Good, O. Bonneau, D. Rowlands, V. Burton, G. Jarai, J. Westwick, M. Thomas (Horsham, United Kingdom). Reduction in serotonin signaling via TPH1 inhibition attenuates the progression of PAH in mice with genetic ablation of endothelial BMPR-II. Eur Respir J 2012; 40: Suppl. 56, 4554
You must
login
to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.
Member's Comments
No comment yet.
You must
Login
to comment this presentation.
Related content which might interest you:
Late Breaking Abstract - Implications of treatable traits and treatment choices on exacerbation risk in moderate-severe asthma
Observational cohort study of pulmonary exacerbations in alpha-1 antitrypsin deficiency
Impact of Dexamethasone on pathogen profile of COVID-19 patients requiring intensive care: a multicentre retrospective study
Related content which might interest you:
Pharmacological activation of Nur77 enhances BMP signalling and inhibits vascular remodelling in pulmonary arterial hypertension
Source: International Congress 2018 – Pathobiology of pulmonary hypertension
Year: 2018
Selective YAP/TAZ inhibition in fibroblasts via dopamine receptor D1 agonism reverses fibrosis
Source: International Congress 2019 – Damage and remodelling in pulmonary fibrosis
Year: 2019
TSC1/mTOR pathway promotes hypoxia-induced pulmonary hypertension in mice
Source: Annual Congress 2012 - Pulmonary circulation: basic mechanisms, animal models and experimental treatments
Year: 2012
Overexpression of serotonin receptor 1B (5HT-1B) responsible for overflow induced experimental pulmonary arterial hypertension development
Source: Annual Congress 2003 - Pathophysiology of the pulmonary circulation
Year: 2003
Endothelin-a receptor antagonists reduce eNOS gene expression in rats with chronic hypoxic pulmonary hypertension
Source: Eur Respir J 2003; 22: Suppl. 45, 271s
Year: 2003
Blockage of serotonin receptors and transporter reduces bleomycin lung fibrosis in mice
Source: Eur Respir J 2005; 26: Suppl. 49, 82s
Year: 2005
Heterozygous SOD2 deletion deteriorated chronic intermittent hypoxia-induced lung inflammation and vascular remodeling through mtROS-NLRP3 signaling pathway
Source: Virtual Congress 2020 – New insights into sleep apnoea: from diagnosis to treatment
Year: 2020
Notch1 signalling regulates endothelial proliferation and apoptosis in pulmonary arterial hypertension
Source: Eur Respir J 2016; 48: 1137-1149
Year: 2016
Dual endothelin-1 receptor antagonism prevents chronic intermittent hypoxia-induced cardiovascular alterations in rats
Source: Annual Congress 2008 - Innovative treatments in sleep disordered breathing
Year: 2008
RB2/p130 gene-enhanced expression downregulates vascular endothelial growth factor expression and inhibits angiogenesis
in vivo
Source: Eur Respir J 2002; 20: Suppl. 38, 3s
Year: 2002
TrkB expression is altered in hypoxia-induced pulmonary hypertension
Source: Eur Respir J 2007; 30: Suppl. 51, 606s
Year: 2007
Glucocorticoids promote TGF-β signalling in lung fibroblasts by upregulating ligand and receptor expression, and uncoupling negative-feedback inhibition
Source: Annual Congress 2010 - Recent developments of molecular pathology and functional genomics in non-neoplastic and neoplastic lung diseases
Year: 2010
Decreased expression of the TGF-beta type I receptor ALK1 in pulmonary arterial hypertension
Source: Annual Congress 2007 - Cellular and molecular aspects of pulmonary hypertension
Year: 2007
Suppression of HIF2 signalling attenuates the initiation of hypoxia-induced pulmonary hypertension
Source: Eur Respir J, 54 (6) 1900378; 10.1183/13993003.00378-2019
Year: 2019
Angiotensin II and hypoxia synergistically induce proliferation in pulmonary artery fibroblasts by a PI-3K and PKC-signaling pathway through HIF-1 a and upregulation of angiotensin II-receptors type I
Source: Eur Respir J 2002; 20: Suppl. 38, 378s
Year: 2002
Acupuncture regulates macrophage polarization in COPD mice model by activating dopamine D2 receptor.
Source: Virtual Congress 2021 – Airway pharmacology: translational and basic science
Year: 2021
Circulating fibrocytes depletion results in reduced lung tumor growth and metastasis by modulating macrophage phenotype, angiogenesis and endothelin system
Source: ERS Lung Science Conference 2017
Year: 2017
Modulation of vascular progenitor cell differentiation by TGFß and endothelin-1 receptor inhibition
Source: Annual Congress 2009 - Pathobiology of pulmonary vascular diseases
Year: 2009
Muscarinic receptors mediate up-regulation of endothelin-1 expression in human lung fibroblasts
Source: Annual Congress 2010 - Regulation of airway pharmacology
Year: 2010
We use cookies on our website to give you the most relevant experience by remembering your preferences and repeat visits. By clicking "Accept", you consent to the use of the cookies.
Accept