Reduction in serotonin signaling via TPH1 inhibition attenuates the progression of PAH in mice with genetic ablation of endothelial BMPR-II

L. Ciuclan, N. Duggan, M. Hussey, R. Good, O. Bonneau, D. Rowlands, V. Burton, G. Jarai, J. Westwick, M. Thomas (Horsham, United Kingdom)

Source: Annual Congress 2012 - Pulmonary circulation: basic mechanisms
Session: Pulmonary circulation: basic mechanisms
Session type: Oral Presentation
Number: 4554
Disease area: Pulmonary vascular diseases

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L. Ciuclan, N. Duggan, M. Hussey, R. Good, O. Bonneau, D. Rowlands, V. Burton, G. Jarai, J. Westwick, M. Thomas (Horsham, United Kingdom). Reduction in serotonin signaling via TPH1 inhibition attenuates the progression of PAH in mice with genetic ablation of endothelial BMPR-II. Eur Respir J 2012; 40: Suppl. 56, 4554

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