Vasopressin is involved in endothelin receptor antagonist-induced fluid retention in rat. Differential effect of selective ETA and dual ETA/ETB receptor antagonists

M. Vercauteren, D. Strasser, E. Vezzali, A. Stalder, M. Iglarz, P. Hess, M. Clozel (Allschwil, Switzerland)

Source: Annual Congress 2012 - Pulmonary circulation: basic mechanisms, animal models and experimental treatments
Session: Pulmonary circulation: basic mechanisms, animal models and experimental treatments
Session type: Thematic Poster Session
Number: 3898
Disease area: Pulmonary vascular diseases

Congress or journal article abstract

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
M. Vercauteren, D. Strasser, E. Vezzali, A. Stalder, M. Iglarz, P. Hess, M. Clozel (Allschwil, Switzerland). Vasopressin is involved in endothelin receptor antagonist-induced fluid retention in rat. Differential effect of selective ETA and dual ETA/ETB receptor antagonists. Eur Respir J 2012; 40: Suppl. 56, 3898

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
The dual endothelin receptor antagonist bosentan reduces TNFα induced GM-CSF release more effectively than the endothelin A receptor antagonist ambrisentan
Source: Annual Congress 2010 - Airway smooth muscle cells
Year: 2010

Unique receptor dissociation kinetics of the novel endothelin receptor antagonist macitentan
Source: Annual Congress 2012 - Pulmonary circulation: basic mechanisms, animal models and experimental treatments
Year: 2012

Pharmacological activities of R-113281, a triple NK1 /NK2 /NK3 neurokinin receptor antagonist
Source: Eur Respir J 2001; 18: Suppl. 33, 264s
Year: 2001

Evaluation of a selective 5-hydroxytryptamine 2B receptor antagonist designed to alter the fibrotic process
Source: International Congress 2017 – Towards new anti-inflammatory and anti-fibrotic agents
Year: 2017




Effect of AVE5883, a dual NK1/NK2 receptor antagonist, on airway responsiveness to neurokinin A in asthma
Source: Eur Respir J 2004; 24: Suppl. 48, 219s
Year: 2004

Dual endothelin receptor antagonism: setting standards in PAH
Source: Eur Respir Rev 2008; 17: 13-18
Year: 2007



In vitro pharmacological profile of CHF 5407, a potent, long-acting and selective muscarinic M3 receptor antagonist
Source: Eur Respir J 2007; 30: Suppl. 51, 25s
Year: 2007

In vivo potent and long-lasting bronchodilator activity of muscarinic M3 receptor antagonist CHF5407
Source: Eur Respir J 2007; 30: Suppl. 51, 26s
Year: 2007

Novel triple neurokinin receptors antagonist CS-003 strongly inhibits neurokinin related responses
Source: Eur Respir J 2006; 28: Suppl. 50, 115s
Year: 2006

Selective versus non-selective endothelin receptor antagonists
Source: Annual Congress 2005 - New treatments in pulmonary hypertension
Year: 2005

Modulation of cortical and respiratory activity by 5-HT2 receptor agonist in the rat
Source: Annual Congress 2008 - Control of breathing and respiratory disorders during sleep
Year: 2008

Superior in vivo efficacy of macitentan: Comparison to other endothelin receptor antagonists
Source: Annual Congress 2012 - Pulmonary circulation: basic mechanisms, animal models and experimental treatments
Year: 2012

Selective YAP/TAZ inhibition in fibroblasts via dopamine receptor D1 agonism reverses fibrosis
Source: International Congress 2019 – Damage and remodelling in pulmonary fibrosis
Year: 2019



The triple neurokinin receptor antagonist CS-003 inhibits neurokinin A (NKA)-induced bronchoconstriction in patients with asthma
Source: Eur Respir J 2003; 22: Suppl. 45, 415s
Year: 2003

Ligand independent activation of the glucocorticoid receptor by long acting β2 agonists
Source: Eur Respir J 2004; 24: Suppl. 48, 317s
Year: 2004

Endothelin receptor antagonists in pulmonary arterial hypertension
Source: Eur Respir J 2008; 31: 407-415
Year: 2008



PKA/cAMP-independent transactivation of glucocorticoid receptor by long acting β2 agonists
Source: Eur Respir J 2006; 28: Suppl. 50, 103s
Year: 2006

Effect of long-acting β2 adrenergic receptor agonists and glucocorticoids on extracellular matrix production
Source: Eur Respir J 2001; 18: Suppl. 33, 475s
Year: 2001

Potential role of memantine in the prevention and treatment of COVID-19: its antagonism of nicotinic acetylcholine receptors and beyond
Source: Eur Respir J, 56 (2) 2001610; 10.1183/13993003.01610-2020
Year: 2020