Tiotropium provides sustained bronchodilation in asthmatics with persistent airflow obstruction uncontrolled despite treatment in accordance with guidelines

H. Kerstjens, P. Paggiaro, M. Vandewalker, E. Beck, M. Engel, R. Sigmund, W. Seibold, P. Moroni-Zentgraf, E. Bateman (Groningen, Netherlands; Pisa, Italy; Columbia, United States Of America; Rüdersdorf Brandenburg, Biberach an der Riss, Ingelheim am Rhein, Germany; Cape Town, South Africa)

Source: Annual Congress 2012 - Translational respiratory medicine in asthma and COPD
Session: Translational respiratory medicine in asthma and COPD
Session type: Thematic Poster Session
Number: 2187
Disease area: Airway diseases

Congress or journal article abstractE-poster

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
H. Kerstjens, P. Paggiaro, M. Vandewalker, E. Beck, M. Engel, R. Sigmund, W. Seibold, P. Moroni-Zentgraf, E. Bateman (Groningen, Netherlands; Pisa, Italy; Columbia, United States Of America; Rüdersdorf Brandenburg, Biberach an der Riss, Ingelheim am Rhein, Germany; Cape Town, South Africa). Tiotropium provides sustained bronchodilation in asthmatics with persistent airflow obstruction uncontrolled despite treatment in accordance with guidelines. Eur Respir J 2012; 40: Suppl. 56, 2187

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
Tiotropium reduces asthma exacerbations in asthmatic patients with persistent airflow obstruction uncontrolled despite treatment in accordance with guidelines
Source: Annual Congress 2012 - Trials in asthma: asthma exacerbations and severe asthma
Year: 2012


Once-daily tiotropium Respimat add-on therapy improves lung function in children with moderate symptomatic asthma, independent of the degree of airflow obstruction
Source: International Congress 2017 – Paediatric asthma: treatment modalities and behavioural issues
Year: 2017


Extrafine triple therapy in patients with asthma and persistent airflow limitation
Source: Eur Respir J, 56 (3) 2000476; 10.1183/13993003.00476-2020
Year: 2020



NVA237, a once-daily anticholinergic, demonstrates sustained bronchodilation and is well tolerated in patients with reversible obstructive airways disease
Source: Annual Congress 2006 - Recent advances in the treatment of COPD
Year: 2006


Bronchodilator reversibility is associated with non-adherence to inhalers in stable asthma patients, without airflow limitation.
Source: Virtual Congress 2020 – Lung function diagnostics
Year: 2020


Improvement in airflow obstruction with inhaled bronchodilators influences the pattern of abdominal muscle recruitment during exercise in COPD
Source: Annual Congress 2010 - Thoracic dynamics and dyspnoea on exercise
Year: 2010


Effects of regular formoterol treatment on airway hyperresponsiveness in patients with mild to moderate asthma
Source: Eur Respir J 2003; 22: Suppl. 45, 285s
Year: 2003

Evaluation of the response of airway obstruction to short-acting inhaled broncodilators with using FIV1 and FEV1 in COPD patients
Source: Eur Respir J 2005; 26: Suppl. 49, 290s
Year: 2005

Predictors of exercise-induced airways obstruction in patients with mild asthma.
Source: Virtual Congress 2020 – Exploring exercise responses in respiratory diseases
Year: 2020


Budesonide/formoterol in a single inhaler provides sustained improvements in lung function in patients with moderate to severe COPD
Source: Eur Respir J 2002; 20: Suppl. 38, 397s
Year: 2002

Long-term asthma treatment guided by airway hyperresponsiveness in children: a randomised controlled trial
Source: Eur Respir J 2007; 30: 457-466
Year: 2007



Maintenance of bronchodilation following tiotropium in patients with mild, moderate and severe COPD in one year clinical trials
Source: Eur Respir J 2001; 18: Suppl. 33, 331s
Year: 2001

Withdrawal of inhaled corticosteroids in COPD patients with mild or moderate airflow limitation: who is suitable for a trial of withdrawal?
Source: International Congress 2019 – Multimorbidity in airway diseases and appropriate inhaled corticosteroid use in COPD
Year: 2019

Tiotropium add-on therapy reduces seasonal peaks of asthma worsening in adults with symptomatic severe asthma
Source: Eur Respir J, 55 (1) 1900964; 10.1183/13993003.00964-2019
Year: 2020



Evaluation of pulmonary function after bronchial thermoplasty in the treatment of severe uncontrolled asthma using forced oscillation technique.
Source: International Congress 2018 – Clinical markers of asthma
Year: 2018

Prolonged bronchodilation following deep inspiration predicts reversibility to salbutamol in severe asthma
Source: Eur Respir J 2005; 26: Suppl. 49, 373s
Year: 2005

Add-on omalizumab therapy reduces clinically significant and severe asthma exacerbations, and improves FEV1 in patients with severe persistent allergic asthma irrespective of age
Source: Eur Respir J 2005; 26: Suppl. 49, 48s
Year: 2005

FeNO-based asthma management results in faster improvement of airway hyperresponsiveness
Source: ERJ Open Res, 4 (4) 00147-2017; 10.1183/23120541.00147-2017
Year: 2018



Tiotropium + olodaterol in patients with moderate to severe COPD with chronic bronchitis and/or emphysema
Source: International Congress 2016 – Pharmacological treatment of COPD: focus on LABA/LAMA combinations
Year: 2016


Rapid protective effect of inhaled fluticasone on airway hyperresponsiveness to AMP in patients with fixed airway obstruction due to asthma but not COPD
Source: Eur Respir J 2006; 28: Suppl. 50, 670s
Year: 2006