Targeting the IL-1β – IL-17A inflammatory axis for the treatment of viral-induced exacerbations of COPD

A. Sichelstiel, A. Trompette, K. Yadava, L. P. Nicod, B. J. Marsland (Lausanne, Switzerland)

Source: Annual Congress 2012 - Animal models of asthma and COPD and late-breaking abstracts on RCT in asthma and COPD
Session: Animal models of asthma and COPD and late-breaking abstracts on RCT in asthma and COPD
Session type: Thematic Poster Session
Number: 2140
Disease area: Airway diseases

Congress or journal article abstract

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
A. Sichelstiel, A. Trompette, K. Yadava, L. P. Nicod, B. J. Marsland (Lausanne, Switzerland). Targeting the IL-1β – IL-17A inflammatory axis for the treatment of viral-induced exacerbations of COPD. Eur Respir J 2012; 40: Suppl. 56, 2140

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
α-b crystallin – a marker for inflammation in COPD patients
Source: Annual Congress 2009 - Airway inflammation and host defence
Year: 2009


A model of poly IC-driven exacerbations of smoke-induced pulmonary inflammation – does it meet researchers needs?
Source: Annual Congress 2009 - Mechanisms of infection: what's new?
Year: 2009


Heliox administration in patients with COPD exacerbation – Technical aspects
Source: Annual Congress 2010 - Mechanical ventilation and weaning
Year: 2010


Role of systemic inflammation mediated by IL-6 and TNF-alpha cytokines in chronic obstructive pulmonary disease and its progression: A three year follow up study
Source: Annual Congress 2013 –Systemic and airway biomarkers in respiratory diseases
Year: 2013

The level of anti-inflammatory cytokine IL-10 in patients with chronic obstructive pulmonary disease of varying severity
Source: Annual Congress 2013 –COPD: new markers of diseases
Year: 2013


Bacterial endotoxin-induced T-lymphocyte immune response is impaired in COPD – effect of moxifloxacin and dexamethasone
Source: Annual Congress 2009 - Inflammatory cells and cytokines
Year: 2009

Chronic non-asthmatic cough – Are we nearer to define the airway pathology?
Source: Annual Congress 2010 - Asthma: clinical aspects and treatment
Year: 2010


Altered inflammasome activity in bacterial acute exacerbations of COPD (AECOPD)
Source: Annual Congress 2013 –Biomarkers in asthma and COPD
Year: 2013


β2 long-acting and anticholinergic drugs synergistically control TGFβ1-mediated neutrophilic inflammation in COPD: An "in vitro" model
Source: Annual Congress 2011 - COPD: clinical studies and animal cell models
Year: 2011


Nontypeable haemophilus influenzae leads to activation of the NLRP3 inflammasome – A possible trigger of chronic bronchial inflammation in COPD
Source: Annual Congress 2012 - Prognostic indices in respiratory infections
Year: 2012

Reprogramming of alveolar macrophages – Prospect of successful treatment in COPD
Source: Annual Congress 2011 - Phagocytes and dendritic cells
Year: 2011


COPD exacerbation severity is associated with impaired macrophage phagocytosis of eosinophils
Source: Annual Congress 2013 –Cell biology and murine models of asthma and inflammation
Year: 2013


Infectious exacerbations of COPD: IL-18 and its relation to markers of inflammation
Source: Annual Congress 2010 - Induced sputum in relation: a fresh look on phenotyping and monitoring
Year: 2010


Interleukin-33 and Th2 cytokines correlate in acute asthma
Source: International Congress 2016 – Clinical and molecular studies in asthma
Year: 2016

Severe asthma: from inflammatory phenotype to treatment
Source: International Congress 2017 – Chinese Programme 2017
Year: 2017


COPD exacerbation: Influence of severity and type of systemic inflammation on the hospitalizations rate
Source: International Congress 2015 – COPD: chronic disease and comorbidities
Year: 2015

Erdosteine – A new drug in the treatment of chronic rhinosinusitis
Source: Annual Congress 2012 - Treatment of asthma, bronchiectasis and cough: inhaler use
Year: 2012


Comorbidities associated with chronic obstructive pulmonary disease (COPD) – A clinical study
Source: Annual Congress 2011 - COPD diagnosis
Year: 2011

Role of IL-1α and IL-1β in cigarette smoke-induced pulmonary inflammation and COPD
Source: Annual Congress 2011 - COPD: clinical studies and animal cell models
Year: 2011


Respiratory muscle function during and after a severe exacerbation of COPD – Preliminary results
Source: Annual Congress 2011 - Respiratory physiotherapy in the intensive care unit and on the ward: breathing exercises and respiratory muscles
Year: 2011