Source: Annual Congress 2012 - Asthma and the genes: from GWAS to next generation transcriptome analyses
Disease area: Airway diseases



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M. Schieck, J.P. Schouten, K. Suttner, S. Michel, P. Rosenstiel, N. Klopp, T. Illig, J. Genuneit, C. Vogelberg, A. von Berg, A. Bufe, A. Heinzmann, T. Frischer, O. Laub, E. Rietschel, B. Simma, E. von Mutius, M. Boezen, M. Kabesch (Hanover, Munich, Kiel, Neuherberg, Ulm, Dresden, Wesel, Bochum, Freiburg, Rosenheim, Germany; Vienna, Feldkirch, Austria; Groningen, Netherlands). A polymorphism in DMRT1 is associated with asthma in boys only and affects promoter activity by allele-specific transcription factor binding. Eur Respir J 2012; 40: Suppl. 56, 1864

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