Enhanced cytotoxic function of NK and NKT-like cells associated with decreased CD94 (Kp43) in the airway in COPD

G. Hodge, V. Mukaro, M. Holmes, P. Reynolds, S. Hodge (Adelaide, Australia)

Source: Annual Congress 2012 - Basic and translational studies in COPD
Session: Basic and translational studies in COPD
Session type: Poster Discussion
Number: 1432
Disease area: Airway diseases

Congress or journal article abstractE-poster

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
G. Hodge, V. Mukaro, M. Holmes, P. Reynolds, S. Hodge (Adelaide, Australia). Enhanced cytotoxic function of NK and NKT-like cells associated with decreased CD94 (Kp43) in the airway in COPD. Eur Respir J 2012; 40: Suppl. 56, 1432

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
Lung CD8+ T cells of COPD patients have low cytotoxic potential and high expression of the inhibitory receptor NKG2A
Source: Annual Congress 2009 - Cell biology of lung disease
Year: 2009


NKG2D-dependent effector function of bronchial epithelium-activated alloreactive T-cells
Source: Eur Respir J 2008; 32: 563-570
Year: 2008



Enhanced expression of IL-18 and increased CD8+ T cells and eosinophils in the airways of asthma death
Source: Annual Congress 2010 - Mechanisms of asthma and lung inflammation
Year: 2010


NKG2D triggers MHC I unrestricted effector function of alloreactive CD8+ T cells
Source: Annual Congress 2008 - Best of lung epithelial cells 2008
Year: 2008


Decreased perforin and granzyme B expression in peripheral blood CD8+ T cells in emphysema
Source: Eur Respir J 2005; 26: Suppl. 49, 105s
Year: 2005

Selective NF-κB inhibition of activated/memory (CD45RO+) T cells by novel mutated IκBα in asthma
Source: Eur Respir J 2007; 30: Suppl. 51, 497s
Year: 2007

CD4+ and CD8+ T lymphocytes display a Th2/Tc2 cytokine profile in COPD
Source: Eur Respir J 2004; 24: Suppl. 48, 319s
Year: 2004

Increased levels of CD4+CD25high and CD4+FoxP3+ T-regulatory cells (Tregs) in patients with different severity of bronchial asthma (BA)
Source: Annual Congress 2011 - Immunology and cell biology of asthma and COPD
Year: 2011

High concentration of antigen induces allergic mice T cells anergy with depressing CD86 expression on antigen-presenting cells
Source: Eur Respir J 2002; 20: Suppl. 38, 28s
Year: 2002

CTLA-4-mediated regulatory phenotype of T-cells in tolerant lung recipients
Source: Eur Respir J 2008; 31: 1167-1176
Year: 2008



Allergen immunotherapy downregulate CD86 expression on dendritic cells and upregulate CTLA-4 expression on T cells in a mouse asthma model
Source: Eur Respir J 2005; 26: Suppl. 49, 135s
Year: 2005

Increase of both blood CXCR3+ and CCR4+ helper T cells associated with severity of asthma
Source: Annual Congress 2005 - Inflammation and remodelling in allergy and asthma
Year: 2005


Increase of activated/memory and decrease of naive T cells with unchanged frequency of regulatory T cells in blood of lung cancer patients
Source: Annual Congress 2009 - Biological and clinical markers in lung cancer
Year: 2009

Diminished levels of IL-7 receptor-positive CD4+ T cells in asthmatic patients are up-regulated by glucocorticoid therapy. No effects on IL-7R-negative regulatory CD4+ T cells
Source: Annual Congress 2010 - Mechanisms of asthma and lung inflammation
Year: 2010


Lung function decline in asthma patients with elevated bronchial CD8, CD4 and CD3 cells
Source: Eur Respir J 2016; 48: 393-402
Year: 2016



The effect of Immunotherapy on the expression of costimulatory pathway molecules on dendritic cells and T cells in asthmatic mice
Source: Eur Respir J 2003; 22: Suppl. 45, 483s
Year: 2003

IL-10-producing CD4+ T cells are essential for the development of airway hyperresponsiveness
Source: Annual Congress 2004 - Modulation of the allergic response in animal models
Year: 2004


The effects of DC expressing PD-L1 on CD4+ T cell in a murine model of allergic airway disease
Source: Annual Congress 2007 - Mouse models of allergic airway inflammation
Year: 2007


Modification of surface antigens in blood CD8+ T-lymphocytes in COPD: effects of smoking
Source: Eur Respir J 2007; 29: 42-50
Year: 2007



Dendritic cells stimulated by agonistic anti-CD40 mAb could elicit activation of lung cancer patients’ autologous cytotoxic T lymphocytes
Source: Eur Respir J 2004; 24: Suppl. 48, 673s
Year: 2004