Non linear kinetics of absorption of inhaled Benso(a)Pyrene in the isolated perfused and ventilated rat lung

P. Ewing, A. Ryrfeldt, P. Gerde (Stockholm, Sweden)

Source: Annual Congress 2005 - Occupational and environmental diseases: a kaleidoscope
Session: Occupational and environmental diseases: a kaleidoscope
Session type: Thematic Poster Session
Number: 1000
Disease area: Airway diseases

Congress or journal article abstract

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
P. Ewing, A. Ryrfeldt, P. Gerde (Stockholm, Sweden). Non linear kinetics of absorption of inhaled Benso(a)Pyrene in the isolated perfused and ventilated rat lung. Eur Respir J 2005; 26: Suppl. 49, 1000

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
Inhaled endothelin-receptor-blockers in acute pulmonary hypertension in an isolated ventilated and buffer perfused rabbit lung model
Source: Eur Respir J 2006; 28: Suppl. 50, 427s
Year: 2006

Inhaled budesonide causes rapid vasoconstriction in the isolated and perfused rat lung
Source: Annual Congress 2008 - Novel experimental approaches to understanding asthma and COPD
Year: 2008

Inflammative responses during reperfusion after cold preservation in the isolated and ventilated perfused rat lung
Source: Eur Respir J 2006; 28: Suppl. 50, 779s
Year: 2006

Features of hypoxic pulmonary vasoconstriction in isolated perfused and ventilated mice lungs
Source: Eur Respir J 2003; 22: Suppl. 45, 270s
Year: 2003

Fluid resorption in the ventilated ex vivo blood-free perfused rat lung
Source: Eur Respir J 2001; 18: Suppl. 33, 196s
Year: 2001

The mediators of allergen-induced bronchoconstriction in the isolated perfused and ventilated guinea pig lung (IPL) are closely similar to those in asthmatics
Source: Eur Respir J 2003; 22: Suppl. 45, 104s
Year: 2003

The evaluation of pulmonary mechanics after administration of furosemide/natrium chloride aerosols in ventilated children with normal lung function
Source: Annual Congress 2008 - Respiratory disorders in paediatric intensive care unit
Year: 2008


Lung absorption half-life of inhaled drugs can be predicted with rat lung slices
Source: International Congress 2015 – New models for treating airway diseases
Year: 2015

Effects of pulmonary perfusion on the airway and parenchymal mechanics in ventilated and nonventilated lungs
Source: Eur Respir J 2001; 18: Suppl. 33, 31s
Year: 2001

Acute increase in pulmonary blood flow elevates airway responsiveness in isolated perfused rat lungs
Source: Annual Congress 2008 - Respiratory pathophysiology from cell and animal research
Year: 2008



A novel tool for the assessment of pulmonary disposition of dry powder aerosols; the isolated and perfused rat lung exposed to budesonide, formoterol and terbutaline
Source: Eur Respir J 2007; 30: Suppl. 51, 352s
Year: 2007

Delivery of inhaled glucocorticoids to ventilated and non-ventilated neonates: in vitro model experiments with novel small volume holding chambers
Source: Eur Respir J 2002; 20: Suppl. 38, 559s
Year: 2002

The effect of partial liquid ventilation compared to surfactant therapy on lung volume in injured ventilated small lungs
Source: Eur Respir J 2006; 28: Suppl. 50, 491s
Year: 2006

Patterns of plasma membrane disruptions distribution in mechanically ventilated lungs
Source: Annual Congress 2011 - Anti-inflammatory strategies in acute lung injury
Year: 2011

Sustained PAP-reduction and tissue cGMP-restoration without systemic NO-generation by aerosolized PAPA-NONOate in an isolated lung model of acute lung injury
Source: Eur Respir J 2004; 24: Suppl. 48, 561s
Year: 2004

The different treatment effects of partial liquid ventilation and surfactant therapy in injured ventilated small lungs
Source: Annual Congress 2008 - Neonatal intensive care: ventilation and beyond
Year: 2008

Survival and pharmacokinetics of gemcitabine in a rat model of isolated lung perfusion
Source: Eur Respir J 2002; 20: Suppl. 38, 179s
Year: 2002

Slow particle dissolution may limit lung absorption of inhaled pharmaceuticals in the lungs
Source: Eur Respir J 2006; 28: Suppl. 50, 210s
Year: 2006

Impact of inhaled NO on development of neonatal rat lung
Source: Annual Congress 2008 - Pulmonary vascular biology
Year: 2008


Perfused lung volume to thoracic gas volume ratio (perfused lung fraction) in subjects with COPD and controls
Source: Annual Congress 2010 - State of the art imaging
Year: 2010