Unfavorable factors associated with false negative results of interferon-gamma release assay for tuberculosis

N. T. L. Hang, L. T. Lien, N. Kobayashi, T. Shimbo, S. Sakurada, P. H. Thuong, L. T. Hong, D. B. Tam, M. Hijikata, I. Matsushita, N. V. Hung, K. Higuchi, N. Harada, N. Keicho (Hanoi, Viet Nam; Tokyo, Japan)

Source: Annual Congress 2011 - Risk assessment for tuberculosis
Session: Risk assessment for tuberculosis
Session type: Thematic Poster Session
Number: 2662
Disease area: Respiratory infections

Congress or journal article abstractE-poster

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
N. T. L. Hang, L. T. Lien, N. Kobayashi, T. Shimbo, S. Sakurada, P. H. Thuong, L. T. Hong, D. B. Tam, M. Hijikata, I. Matsushita, N. V. Hung, K. Higuchi, N. Harada, N. Keicho (Hanoi, Viet Nam; Tokyo, Japan). Unfavorable factors associated with false negative results of interferon-gamma release assay for tuberculosis. Eur Respir J 2011; 38: Suppl. 55, 2662

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
Smoking is a strong independent risk factor for indeterminate and false negative IGRA results
Source: Annual Congress 2011 - What is new in tuberculosis immunodiagnosis?
Year: 2011

Indeterminate IFN-? release assay test results predict poor prognosis of active pulmonary tuberculosis
Source: International Congress 2019 – Tuberculosis: diagnosis and scores
Year: 2019


Can we predict who will develop TB among those with a positive interferon-? release assay (IGRA)?
Source: International Congress 2018 – Important changes in the management of tuberculosis
Year: 2018


IFN γ tests for tuberculosis – false positives with other T cell disease processes?
Source: Annual Congress 2008 - Interferon-gamma methods for the diagnosis of tuberculosis infection and disease
Year: 2008

The value of interferon-gamma releasing assays (IGRA) determining latent tuberculosis infection in renal transplant candidates
Source: International Congress 2016 – Active and latent tuberculosis: biomarkers
Year: 2016


Comparison of whole-blood interferon-gamma release assay and tuberculin skin test results for the prediction of active tuberculosis disease in HIV-infected individuals
Source: Annual Congress 2009 - Tuberculosis and HIV co-infection
Year: 2009


Clinical evaluation of interferon-gamma release assay (IGRA) in patients with nontuberculous mycobacterial disease
Source: Annual Congress 2012 - Non-tuberculous and tuberculous mycobacterial infections: from epidemiology to clinical findings
Year: 2012

No added value of interferon-gamma release to a prediction model for childhood tuberculosis
Source: Eur Respir J 2016; 47: 223-232
Year: 2016



False-negative interferon gamma release assay results in active tuberculosis: a TBNET study
Source: Eur Respir J 2015; 45: 279-283
Year: 2015


IFN-gamma production in response to RD1 assays correlate with TST size and with the frequency of exposure to the index case in contacts recently exposed to mycobacterium tuberculosis
Source: Annual Congress 2007 - New methods to diagnose tuberculosis infection and disease and problems in tuberculosis care
Year: 2007


Basic factors, influencing treatment efficacy of patients with newly detected sputum positive destructive lung tuberculosis
Source: Eur Respir J 2004; 24: Suppl. 48, 724s
Year: 2004

Performance outcomes of standardized antigen-driven IFN-g release assays for the diagnosis of active TB in a high burden setting
Source: Annual Congress 2008 - Interferon-gamma release assay tests for diagnosing tuberculosis infection and disease
Year: 2008

Do kinetics of interferon-gamma responses predict TB relapse?
Source: Annual Congress 2011 - Risk assessment for tuberculosis
Year: 2011

Interferon-gamma release assays (IGRA) for latent tuberculosis infection (LTBI) in children
Source: Annual Congress 2011 - Tuberculosis in pregnancy and childhood
Year: 2011


False positive chlamydia pneumonia IgM assay induced by rheumatoid factor
Source: Eur Respir J 2006; 28: Suppl. 50, 3s
Year: 2006

The risk of tuberculosis related to tumour necrosis factor antagonist therapies: a TBNET consensus statement
Source: Eur Respir J 2010; 36: 1185-1206
Year: 2010



Additional analysis of antigen-specific Interleukin-2 release does not improve the performance of IGRAs for the differentiation of different states of mycobacterium tuberculosis infection
Source: International Congress 2014 – Future frontiers in the diagnosis of Mycobacterium tuberculosis infection
Year: 2014


Negative effect of ferritin levels on T-SPOT.TB, an enzyme-linked immunospot based interferon-gamma release assay using Mycobacterium tuberculosis specific antigens, in the smear-positive active pulmonary tuberculosis.
Source: International Congress 2018 – Diagnosis of tuberculosis
Year: 2018


Comparative study of the usefulness of TST and three interferon-gamma release assasys (IGRAs) for the differential diagnosis of pulmonary tuberculosis
Source: Annual Congress 2011 - Tuberculin skin tests, interferon-gamma release assays and beyond
Year: 2011

Diagnostic performance of the interferon gamma release assay in elderly patients and clinical factors to support the diagnosis of active tuberculosis
Source: Annual Congress 2012 - Tuberculosis and immunologic assays
Year: 2012