Protein phosphatase PP2A activation by formoterol reverses corticosteroid insensitivity Source: Annual Congress 2009 - Airway cell biology Year: 2009
Formoterol restores oxidative stress-induced corticosteroid insensitivity via activation of protein phosphatase PP2A Source: Annual Congress 2012 - Cellular signalling mechanisms in the airways Year: 2012
Formoterol enhances glucocorticoid receptor nuclear translocation in steroid-insensitive severe asthma Source: Eur Respir J 2004; 24: Suppl. 48, 250s Year: 2004
Synergistic action of formoterol on budesonide-generated decrease of proteoglycan production by activated lung fibroblasts is mediated via β-adrenergic receptor and is dependent on glucocorticoid receptor Source: Eur Respir J 2004; 24: Suppl. 48, 345s Year: 2004
Leptomycin B (LMB) promotes nuclear retention of fluticasone furoate (FF)-activated glucocorticoid receptor (GR) Source: Annual Congress 2010 - Regulation of airway pharmacology Year: 2010
A novel macrolide/fluoroketolide, solithromycin (CEM-101), reverses corticosteroid insensitivity via activation of protein phosphatase PP2A Source: Annual Congress 2011 - Phagocytes and dendritic cells Year: 2011
Importin-7 knockdown reduces corticosteroid induced glucocorticoid receptor nuclear localisation and suppression of IL-1beta induced CXCL8 Source: Annual Congress 2013 –Novel mechanisms for established drugs for asthma and COPD management Year: 2013
Gene transfer of a β-adrenergic receptor kinase inhibitor up-regulated levels of β-adrenergic receptor and cAMP in asthmatic murine lung Source: Eur Respir J 2005; 26: Suppl. 49, 580s Year: 2005
MAP kinase phosphatase 1 mediates glucocorticoid inhibition of CD38 expression in human airway smooth muscle Source: Annual Congress 2008 - Basic science in asthma and COPD II Year: 2008
Modulation of bradykinin (BK)-induced lung fibroblast proliferation and differentiation by budesonide (Bud) and formoterol (Form) involves the inhibition of ERK1/2 phosphorylation and Ca2+ mobilization Source: Annual Congress 2009 - Translational models of lung disease Year: 2009
A novel target of formoterol, a dual-specificity phosphatase DUSP4 on regulation of corticosteroid budesonide sensitivity Source: Annual Congress 2011 - Understanding disease and drug mechanisms Year: 2011
G-protein mediated EGFR transactivation induces mucin production Source: Annual Congress 2003 - Cellular and molecular mechanisms in epithelium injury and repair Year: 2003
Budesonide and formoterol rapidly and effectively inhibit ERK1/2 phosphorylation in bradykinin-stimulated human lung fibroblasts Source: Annual Congress 2008 - Novel experimental approaches to understanding asthma and COPD II Year: 2008
Lack of glucocorticoid receptor activation by formoterol and salmeterol in human bronchial epithelial cells Source: Eur Respir J 2003; 22: Suppl. 45, 454s Year: 2003
Synergistic inhibition of salmeterol with fluticasone propionate or rolipram on stimulated eosinophil binding of β2 -integrin to ICAM-1 and cytosolic gIV-phospholipase A2 activation Source: Eur Respir J 2003; 22: Suppl. 45, 455s Year: 2003
The pro-apoptotic effect of cysteinyl leukotriene receptor (CysLT-R) antagonist montelukast is mediated by CysLT-Rs expression on antigen-stimulated T cells Source: Eur Respir J 2003; 22: Suppl. 45, 100s Year: 2003
Fluticasone furoate, a novel corticosteroid, maintains glucocorticoid receptor nuclear localisation for 24 hours after washout in monocytes Source: Annual Congress 2011 - Translational models of disease Year: 2011
Effects of TGF-beta and budesonide on MAPK phosphorylation, IL-6/IL-11 secretion, and cell proliferation in human lung fibroblasts Source: Eur Respir J 2006; 28: Suppl. 50, 662s Year: 2006
Involvement of C/EBPbeta and delta in lung glucocorticoid signaling Source: Eur Respir J 2002; 20: Suppl. 38, 372s Year: 2002
The serum and glucocorticoid inducible kinase in alveolar transport regulation Source: Annual Congress 2009 - Novel regulators of alveolar liquid clearance Year: 2009