Common functional variants of MMP-1, MMP-3, ACE-1 and 5-HTT genes are associated with distinct symptoms in COPD

N. Kuzubova, A. Chukhlovin, E. Morosova, A. Totolian, O. Titova (Saint-Petersburg, Russian Federation; , Rwanda)

Source: Annual Congress 2011 - Genes, environment and obstruction
Session: Genes, environment and obstruction
Session type: Oral Presentation
Number: 1736
Disease area: Airway diseases

Congress or journal article abstractSlide presentation

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
N. Kuzubova, A. Chukhlovin, E. Morosova, A. Totolian, O. Titova (Saint-Petersburg, Russian Federation; , Rwanda). Common functional variants of MMP-1, MMP-3, ACE-1 and 5-HTT genes are associated with distinct symptoms in COPD. Eur Respir J 2011; 38: Suppl. 55, 1736

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
Association of TNF, IL8, NOS1, NOS3 and NRAMP1 gene polymorphisms with COPD exacerbation etiology
Source: Eur Respir J 2005; 26: Suppl. 49, 95s
Year: 2005

MMP-3 serum levels and MMP3 -1171insA promoter polymorphism in patients with COPD
Source: International Congress 2014 – Basic and translational research in asthma and COPD
Year: 2014


Are there serum levels of MMP-2 and MMP-9 may be markers of COPD phenotypes?
Source: Annual Congress 2012 - COPD treatment and varia
Year: 2012


Associations of an intron MMP9 polymorphism and the serum levels of gelatinase B with the development of COPD
Source: International Congress 2019 – New molecular signatures in COPD, lung cancer and a1-antitrypsin deficiency
Year: 2019


Genes affecting mRNA stability and metalloproteinase inhibitor RECK are down-regulated in patients with COPD
Source: Annual Congress 2013 –New insights into epigenetic mechanisms in the lung
Year: 2013



The functional polymorphisms in the IL-18 gene promoter is associated with the pathogenesis of sarcoidosis
Source: Eur Respir J 2003; 22: Suppl. 45, 180s
Year: 2003

The promoter polymorphism -1562C/T in matrix metalloproteinase-9 and COPD severity
Source: Eur Respir J 2006; 28: Suppl. 50, 825s
Year: 2006

The promoter polymorphism -1562C/T in matrix metalloproteinase-9 and COPD severity
Source: Eur Respir Rev 2006; 15: 230-232
Year: 2006



MMP2 -1306C>T polymorphism and the enzyme plasma levels in patients with COPD
Source: International Congress 2015 – Translational research in respiratory care: new findings
Year: 2015


Gene variants in IL18R1 and IL18RAP are associated with IgE and 25-hydroxy-D3 levels in asthma families
Source: Annual Congress 2008 - Risk factors for childhood asthma and allergy
Year: 2008

Association of the plasma levels and gene polymorphism IL12B, IL13 with severe asthma in Siberian children
Source: Virtual Congress 2021 – Biomarkers and risk factors in childhood asthma
Year: 2021


The role of genetic polymorphisms of glutation-S-transferase μ1 (GSTM1) and gelatinase B (MMP9) in the risk of COPD development
Source: Annual Congress 2003 - Alpha-1 antitrypsin deficiency and COPD
Year: 2003


Association of NOS3 gene polymorphisms with the activity of proteases and antiproteases in COPD patients
Source: Annual Congress 2009 - Genetics in the smokers corner: from inflammation in smokers via COPD to cancer
Year: 2009


Plasma uteroglobin-related protein 1 (Ugrp1) levels is associated with Ugrp1 -112G/A polymorphism and the severity of asthma
Source: Eur Respir J 2006; 28: Suppl. 50, 592s
Year: 2006

Polymorphisms of MDR1, ADRB2 and IL13 genes are markers of therapy-resistant bronchial asthma (BA) in Russian patients
Source: Annual Congress 2012 - Recent progress in mechanisms and diagnostics of COPD and asthma
Year: 2012


Polymorphic variants of genes ADRB2, NR3C1, MDR1 in patients with chronic obstructive pulmonary disease and obesity
Source: International Congress 2015 – Genetics and environmental factors in phenotypes of asthma and COPD
Year: 2015


Impact of -1562 C/T polymorphism of MMP9 gene on COPD susceptibility in Polish patients.
Source: International Congress 2014 – Genetics and environmental factors underlying asthma and COPD
Year: 2014

Association of -308G/A polymorphism of TNF gene with the activity of proteases and antiproteases in sputum in COPD patients
Source: Annual Congress 2008 - Advances in functional genomics of neoplastic and non-neoplastic lung diseases
Year: 2008

Genetic polymorphisms in MMP9 and TIMP2 genes and risk of chronic obstructive pulmonary disease
Source: Annual Congress 2009 - Genetics in the smokers corner: from inflammation in smokers via COPD to cancer
Year: 2009

DPP10 protein expression is associated with the pathogenesis of asthma and COPD
Source: Eur Respir J 2005; 26: Suppl. 49, 231s
Year: 2005