Growth hormone releasing hormone-receptor antagonist MIA-602 modulates lung inflammation, cellular signal transduction, and promotes apoptosis of mouse lung fibroblasts Source: Virtual Congress 2020 – Translational therapeutic advances Year: 2020
A novel receptor antagonist, c-027, inhibits airway contraction in human and murine models of allergen, independent of inflammatory mediator release Source: Annual Congress 2009 - Novel mechanisms in the pathogenesis of asthma Year: 2009
IgE regulatory role of histamine and histamine receptors in asthma patients Source: Eur Respir J 2004; 24: Suppl. 48, 353s Year: 2004
Inhaled glucocorticoids and β-2 agonists regulate cytokine secretion from circulating blood cells Source: Annual Congress 2008 - Advances in the treatment and pathogenesis of pulmonary diseases Year: 2008
A decreased expression of leptin receptor may contribute to the pathogenesis of the allergic rhinitis Source: Annual Congress 2010 - Asthma: clinical aspects and treatment Year: 2010
A fully dissociated glucocorticoid receptor modulator reduces airway hyperresponsiveness and inflammation in a murine model of asthma Source: Annual Congress 2010 - Pre-clinical models of airways disease Year: 2010
The epidermal growth factor receptor mediates allergic airway remodelling in the rat Source: Eur Respir J 2008; 32: 1213-1223 Year: 2008
Association of adrenal response in asthmatic children on inhaled steroids with polymorphisms in the genes of glucocorticoid receptor (GR) and corticotropin releasing hormone receptor 1 (CRHR1) Source: Annual Congress 2009 - Difficult asthma in children: diagnostic and therapeutic challenges Year: 2009
Corticosteroid-dependent transcription is reduced by inflammatory stimuli in human airway epithelial cells: Rescue by long-acting β2 -adrenoceptor agonists Source: Annual Congress 2011 - Epithelial cells: role in health and disease Year: 2011
Serotonin (5-hydroxytryptamine) modulates cytokine and chemokine production in lipopolysaccharide-primed human monocytes via stimulation of different 5-HT receptor subtypes Source: Annual Congress 2005 - Inflammation and remodelling in allergy and asthma Year: 2005
A long-acting β2-adrenergic receptor agonist increases cAMP-induced chloride secretion in human airway epithelial cells Source: Eur Respir J 2004; 24: Suppl. 48, 555s Year: 2004
Concomitant exposure to nicotine and endotoxin in vitro induces murine airway hyperreactivity possibly via nicotine-induced upregulation of toll-like receptors Source: Annual Congress 2011 - New mechanisms in airway disease Year: 2011
Growth hormone-releasing hormone receptor antagonist MIA-602 modulates mouse lung inflammation and fibrosis due to bleomycin Source: International Congress 2018 – New insights in the signalling pathways that underlie IPF pathophysiology Year: 2018
Remicade suppresses cytokine-induced up-regulation of bradykinin receptor-mediated airway smooth muscle contractions Source: Annual Congress 2005 - Inflammation and the airway smooth muscle: cellular and pharmacological interactions Year: 2005
Evidence for potential autocrine regulation of human airway smooth muscle cell functions by neurokinins: modulation of gene expression by glucocorticoids Source: Eur Respir J 2003; 22: Suppl. 45, 11s Year: 2003
Effect of muscarinic receptors inhibition on cytokine release and inflammatory cells infiltration in the airway of cat as an animal model for COPD Source: Annual Congress 2012 - Animal models of asthma and COPD and late-breaking abstracts on RCT in asthma and COPD Year: 2012
Effects of TH9507, a growth hormone releasing factor (GRF) analog, on functional performance in patients with COPD Source: Eur Respir J 2004; 24: Suppl. 48, 245s Year: 2004
Bronchial thermoplasty may increase steroid sensitivity by upregulating the expression of the glucocorticoid receptor Source: Virtual Congress 2020 – Asthma pharmacology: clinical trials and mechanistic insights Year: 2020
Toll-like receptor stimulation induces airway hyperresponsiveness to bradykinin, an effect mediated by JNK and NF-κB signaling pathways Source: Eur Respir J 2005; 26: Suppl. 49, 732s Year: 2005
Growth hormone releasing hormone receptor (GHRH-R) antagonist MIA-602 modulates fibrosis and gene expression in lungs of bleomycin-treated mice Source: International Congress 2019 – Translational aspects of idiopathic interstitial pneumonia Year: 2019