PGD2 biosynthesis in several human mast cell models is catalyzed by cycloxygenase-1

J. H. Choi, S. E. Dahlén, G. Nilsson (Stockholm, Sweden)

Source: Annual Congress 2011 - Mechanisms of allergic inflammation of the airways
Session: Mechanisms of allergic inflammation of the airways
Session type: Oral Presentation
Number: 1400
Disease area: Airway diseases

Congress or journal article abstractSlide presentation

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
J. H. Choi, S. E. Dahlén, G. Nilsson (Stockholm, Sweden). PGD2 biosynthesis in several human mast cell models is catalyzed by cycloxygenase-1. Eur Respir J 2011; 38: Suppl. 55, 1400

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
Effects of zileuton on leukotriene formation in human blood cells and expression of enzymes in the biosynthetic pathway
Source: Eur Respir J 2006; 28: Suppl. 50, 316s
Year: 2006

COX-1 driven biosynthesis of PGD2 during activation of human mast cells prevents formation of other prostanoids
Source: Virtual Congress 2020 – Novel molecular markers and targets for asthma phenotypes
Year: 2020


Curcumin induces glutathione biosynthesis and inhibits NF-κB activation and interleukin-8 release in alveolar epithelial cells
Source: Eur Respir J 2004; 24: Suppl. 48, 29s
Year: 2004

Epoxyeicosatrienoates are the dominant eicosanoids in human lungs upon microbial challenge
Source: Eur Respir J 2010; 36: 1088-1098
Year: 2010



Dexamethasone accelerates catabolism of leukotriene C4 in bronchial epithelial cells
Source: Eur Respir J 2003; 22: 35-42
Year: 2003



Inhibition of the glycogen synthase kinase 3β reduces steroid function in human monocytes
Source: Annual Congress 2010 - Regulation of airway pharmacology
Year: 2010

Effect of phosphodiesterase IV inhibitors on eotaxin expression in bronchial epithelial cells – Comparison between immortalized and primary line
Source: Annual Congress 2011 - Lung cell biology
Year: 2011


COX inhibition enhances remodelling processes in human lung fibroblasts
Source: Annual Congress 2010 - Regulation of airway pharmacology
Year: 2010

Involvement of human bronchial epithelial cells in proliferation control of T-cells via reversible STAT5 dephosphorylation mediated by nitric oxide (NO)
Source: Eur Respir J 2002; 20: Suppl. 38, 207s
Year: 2002

Xanthine oxidase inhibitors reduce rhinovirus induced IL-8 and GRO-α production in bronchial epithelial cells
Source: Eur Respir J 2007; 30: Suppl. 51, 721s
Year: 2007

GB001 potently inhibits PGD2 metabolite-induced DP2-mediated cell signaling and eosinophil activation
Source: Virtual Congress 2020 – Asthma science: novel targets and mechanisms
Year: 2020


IL-13 enhances GSNO reductase activity and decreases intracellular S-nitrosothiols in lung epithelial cells
Source: Eur Respir J 2006; 28: Suppl. 50, 103s
Year: 2006

IL-8 and COX-2 expression is regulated through cPLA2-derived arachidonate metabolites in human lung cells
Source: Annual Congress 2003 - Intracellular signalling and regulation of cytokine production
Year: 2003


An inhibitor of HMG-CoA reductase, pitavastatin, inhibits rhinovirus infection in human tracheal epithelial cells
Source: Annual Congress 2009 - Lung cell biology and immunology
Year: 2009


Melatonin promoted the chemotaxin expression in human lung epithelial cell stimulated with TNF-α
Source: Eur Respir J 2003; 22: Suppl. 45, 560s
Year: 2003

Induction of apoptosis in murine alveolar epithelial cells by a proteasome inhibitor
Source: Eur Respir J 2001; 18: Suppl. 33, 358s
Year: 2001

Proteasome inhibitors modulate chemokine production in lung epithelial and monocytic cells
Source: Eur Respir J 2004; 24: 40-48
Year: 2004



Effects of MAPK inhibitors on H2O2-induced IL-8 production and cell death in primary cultures of human bronchial epithelial cells
Source: Eur Respir J 2004; 24: Suppl. 48, 218s
Year: 2004

Inhibition by reproterol of cAMP phosphodiesterase in cultured P815111 mouse mastocytoma cells
Source: Eur Respir J 2001; 18: Suppl. 33, 407s
Year: 2001

SIRT6-induced activation of autophagy inhibits CSE-induced bronchial epithelial cell senescence
Source: Annual Congress 2011 - Epithelial cells: role in health and disease
Year: 2011