Inhibition of LPS-induced neutrophil recruitment in the lungs correlates with modulation of neutrophil CD11b expression using the selective CXCR2 receptor antagonist SB-656933 Source: Eur Respir J 2004; 24: Suppl. 48, 218s Year: 2004
The selective CXCR2 receptor antagonist SB-656933 inhibits CXCL1-induced neutrophil CD11b expression in human whole blood Source: Eur Respir J 2004; 24: Suppl. 48, 218s Year: 2004
The purinergic receptor P2Y2 mediates chemotaxis of dendritic cells and eosinophils in allergic lung inflammation Source: Annual Congress 2010 - Asthma: basic science and clinical studies Year: 2010
IL-17, produced by lymphocytes and neutrophils, is necessary for lipopolysaccharide- but not allergen-induced airway neutrophilia Source: Eur Respir J 2002; 20: Suppl. 38, 618s Year: 2002
Differential inhibition of PAF- and eotaxin-induced human eosinophil chemotaxis by wortmannin Source: Eur Respir J 2002; 20: Suppl. 38, 30s Year: 2002
SCH 527123, a CXCR2 antagonist, inhibits ozone-induced airway neutrophilia in healthy subjects Source: Annual Congress 2007 - New drugs for COPD Year: 2007
Inhaled CCR1 antagonist AZD4818 reduces leucocyte influx in the rat lipopolysaccharide (LPS) lung inflammation model Source: Annual Congress 2009 - Preclinical models in drug development Year: 2009
Stimulation of P2 purinergic receptors induces the release of eosinophil cationic protein and interleukin-8 from human eosinophils Source: Eur Respir J 2003; 22: Suppl. 45, 548s Year: 2003
Inhibition of eosinophil migration by montelukast, a cysteinyl leukotriene receptor antagonist, through down regulation of plasmin activity Source: Eur Respir J 2004; 24: Suppl. 48, 36s Year: 2004
The pro-apoptotic effect of cysteinyl leukotriene receptor (CysLT-R) antagonist montelukast is mediated by CysLT-Rs expression on antigen-stimulated T cells Source: Eur Respir J 2003; 22: Suppl. 45, 100s Year: 2003
LSC 2011 Abstract: P2Y2 receptor regulates VCAM-1 membrane and soluble forms and eosinophil accumulation during lung inflammation Source: Annual Congress 2011 - Experimental modulation of airway inflammation Year: 2011
GB001 potently inhibits PGD2 metabolite-induced DP2-mediated cell signaling and eosinophil activation Source: Virtual Congress 2020 – Asthma science: novel targets and mechanisms Year: 2020
Phosphoinositide 3-kinase γ required for lipopolysaccharide-induced transepithelial neutrophil trafficking in the lung Source: Eur Respir J 2010; 35: 1137-1147 Year: 2010
Neutrophil airway influx by platelet-activating factor in asthma: role of adhesion molecules and LTB4 expression Source: Eur Respir J 2003; 22: 290-297 Year: 2003
Mucosal explant induced migration of T-cells from severe asthmatics is inhibited by CCR4 antagonism Source: Annual Congress 2012 - Mechanisms of asthma Year: 2012
Endotoxin-induced IL-17 release by murine T-lymphocytes: interactions with airway macrophages Source: Eur Respir J 2001; 18: Suppl. 33, 408s Year: 2001
Roflumilast potently inhibits CXCL1 mediated neutrophil migration in COPD patients Source: Annual Congress 2011 - COPD: clinical studies and animal cell models Year: 2011
Protease activated receptor 2 (PAR2) antagonism reduces pro-inflammatory cytokine production in bronchial epithelial cells Source: Virtual Congress 2020 – Novel immunopathological mechanisms of lung disease: knowledge from translational studies Year: 2020
Antigen-induced airway hyperresponsiveness and eosinophilia in mice is inhibited by the endothelin receptor antagonist SB217242 Source: Eur Respir J 2001; 18: Suppl. 33, 349s Year: 2001
Montelukast inhibits both resting and GM-CSF-stimulated eosinophil adhesion to VCAM-1 under flow conditions Source: Eur Respir J 2006; 28: Suppl. 50, 433s Year: 2006