In the past decennium there has been considerable progress in research determining the genetics of complex diseases, including asthma and COPD and other complex diseases. A first research seminar on "Post genome respiratory epidemiology" has been held in 2002. The primary aim was to sensitize respiratory epidemiologists to the potentials of genetic and genomic research. Since epidemiologists and clinicians have incorporated genetic aspects in their studies by candidate gene approaches and genome wide search, debated aspects are no longer whether genetics should enter respiratory epidemiology but how.
This second "Post Genome Respiratory Epidemiology" ERS research seminar organised in cooperation with Ga2len aimed to:
- illustrate current challenges in epidemiology in relation to genetics, genomics and post genomics in asthma and COPD by combining states of the art regarding the field and other views from a broaden perspective
- favour interdisciplinary approaches for defining strategies, methods, interpretation of results - Assessment of their potentials and limits
GWA to study the genetics of asthma and in other diseases - advances and challenges W. Cookson (London, United Kingdom)
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Gene-environment interactions in asthma in the GWA era F. Martinez (Tucson, Az, United States of America)
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COPD - Current challenges D. S. Postma (Groningen, The Netherlands)
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Crohn's disease, perspective of another complex disease M. Georges (Liege, Belgium)
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Genetic variation and common diseases. Where are we? Where to go? F. Demenais (Paris, France)
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Public health genomics: closing the gap between gene discoveries and population health M. Khoury (Atlanta, Ga, United States of America)
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Ethical issues in genetic research A. Cambon-Thomsen (Toulouse Cedex, France)
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Some current challenges in statistical methods to illuminate disease genetics D. Balding (London, United Kingdom)
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Genome wide associations D. Thomas (Los Angeles, Ca, United States of America)
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From genomics to proteomics I. Gut (Evry Cedex , France)
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Studying pathways - Why and how D. Vercelli (Tucson, Az, United States of America)
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