A step-change in asthma. The Lancet/ERS symposium

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Chairs: K. F. Rabe (Leiden, The Netherlands), S. Holgate (Southampton, United Kingdom)
Aims: To summarise for a wide audience current understanding of the disease, highlight the challenges ahead, and stimulate research into new areas.

A critical evaluation of the relevance of different asthma phenotypes for clinical practice I. Pavord (Leicester, United Kingdom)
Key mechanisms in asthma beyond the Th1/Th2 paradigm G. Anderson (Melbourne, Australia)
Complexity in chronic asthma and COPD: implications for risk assessment, disease progression and control U. Frey (Bern, Switzerland)
New targets for drug development in asthma I. M. Adcock (London, United Kingdom)