Acute lung injury. Do we know what it is? A look at different models
Symposium Chairs: S. Uhlig (Aachen, Germany), M. Takata (London, United Kingdom)
Aims: This symposium aims to compare established experimental models of acute lung injury (ALI). To that end, each speaker will apply a similar set of criteria to compare one particular model with the most frequently used model, the endotoxin model. This symposium will identify benefits and, in particular, underline shortcomings of currently used ALI models for the study of human disease. As particular attention is given to endotoxin models, one speaker speaks from the perspective of the animal model, while one acute respiratory distress syndrome (ARDS) clinician-scientist speaks from the human ALI/ARDS perspective. The session should provide valuable mechanistic insights into the disease processes of the models and of ALI/ARDS.