Clinical and translational studies of asthma and COPD: novel mechanisms

Oral Presentation
Chairs: L. Uller (Lund, Sweden), F. Salgado Castro (Santiago De Compostela, Spain)
Introduction
L. Uller (Lund, Sweden), F. Salgado Castro (Santiago De Compostela, Spain)
Webcast
Webcast
Calcaratarin D reduces airway inflammation and oxidative damage by modulating alveolar macrophages via Michael acceptor system
W. Liao (Singapore, Singapore), Y. Foo (Singapore, Singapore), T. Tran (Singapore, Singapore), W. Wong (Singapore, Singapore)
Congress or journal article abstractWebcastPDF journal article, handout or slidesE-poster
Congress or journal article abstractWebcastPDF journal article, handout or slidesE-poster
Effect of tezepelumab on seasonal exacerbations in patients with severe, uncontrolled asthma grouped by blood eosinophil count
J. Corren (Los Angeles, United States), A. Menzies-Gow (London, United Kingdom), C. Ambrose (Gaithersburg, United States), G. Colice (Gaithersburg, United States), S. Roseti (Gaithersburg, United States), Å. Hellqvist (Gothenburg, Sweden), K. Kmita (Warsaw, Poland), A. Lindsley (Thousand Oaks, United States), B. Cook (Gaithersburg, United States)
Congress or journal article abstractWebcastPDF journal article, handout or slidesE-poster
Congress or journal article abstractWebcastPDF journal article, handout or slidesE-poster
Extracellular HSP60 induces airway wall remodeling via Toll-Like-Receptors in mice
L. Fang (Basel, Switzerland), J. Li (Guangdong, China), L. Zhou (Basel, Switzerland), N. Segueni (Orléans, France), B. Ryffel (Orléans, France), M. Tamm (Basel, Switzerland), M. Roth (Basel, Switzerland)
Congress or journal article abstractWebcastPDF journal article, handout or slidesE-poster
Congress or journal article abstractWebcastPDF journal article, handout or slidesE-poster
Identification of steroid-response pathways related to FeNO levels in asthma bronchial epithelium
M. Menzel (Copenhagen, Denmark), M. Hvidtfeldt (Copenhagen, Denmark), D. Klein (Copenhagen, Denmark), J. Nieto-Fontarigo (Lund, Sweden), A. Sverrild (Copenhagen, Denmark), L. Uller (Lund, Sweden), C. Porsbjerg (Copenhagen, Denmark)
Congress or journal article abstractWebcastPDF journal article, handout or slidesE-poster
Congress or journal article abstractWebcastPDF journal article, handout or slidesE-poster
Tozorakimab: a dual-pharmacology anti-IL-33 antibody that inhibits IL-33 signalling via ST2 and RAGE/EGFR to reduce inflammation and epithelial dysfunction
I. Scott (Cambridge, United Kingdom), E. England (Cambridge, United Kingdom), D. Rees (Cambridge, United Kingdom), T. Erngren (Gothenburg, Sweden), C. Chaillan Huntington (Cambridge, United Kingdom), K. Houslay (Cambridge, United Kingdom), D. Sims (Gaithersburg, United States), C. Hollins (Cambridge, United Kingdom), E. Hinchy (Cambridge, United Kingdom), C. Colley (Cambridge, United Kingdom), D. Corkill (Cambridge, United Kingdom), E. Cohen (Cambridge, United Kingdom)
Congress or journal article abstractWebcastPDF journal article, handout or slidesE-poster
Congress or journal article abstractWebcastPDF journal article, handout or slidesE-poster
Effects of anti-IL 17 on inflammation in Asthma, COPD and Asthma-COPD models
F. Almeida (São Paulo (SP), Brazil), L. Camargo (São Paulo (SP), Brazil), N. Martins (São Paulo (SP), Brazil), J. Lourenço (São Paulo (SP), Brazil), S. Bezerra (São Paulo (SP), Brazil), B. Saraiva-Romanholo (São Paulo (SP), Brazil), E. Leick (São Paulo (SP), Brazil), F. Q.S. Lopes (São Paulo (SP), Brazil), C. Prado (Santos (SP), Brazil), R. Righetti (São Paulo (SP), Brazil), I. Tibério (São Paulo (SP), Brazil)
Congress or journal article abstractWebcastPDF journal article, handout or slidesE-poster
Congress or journal article abstractWebcastPDF journal article, handout or slidesE-poster
The impact of anti-IL5 therapies on patients with severe eosinophilic asthma: a proteomic approach
P. Cameli (Siena, Italy), L. Vantaggiato (Siena , Italy), M. D'Alessandro (Siena , Italy), L. Bergantini (Siena, Italy), E. Shaba (Siena, Italy), A. Carleo (Hannover, Germany), F. Di Giuseppe (Chieti, Italy), S. Angelucci (Chieti, Italy), L. Bini (Siena, Italy), E. Bargagli (Siena, Italy), C. Landi (Siena, Italy)
Congress or journal article abstractWebcastPDF journal article, handout or slidesE-poster
Congress or journal article abstractWebcastPDF journal article, handout or slidesE-poster
Montelukast reverses ß2-adrenoceptor tolerance in airway smooth muscle and shows a synergic effect in vivo
I. Cerqua (Napoli, Italy), E. Granato (Napoli, Italy), M. Muscarà (São Paulo, Brazil), G. Cirino (Napoli, Italy), B. Severino (Napoli, Italy), R. Pavese (Salerno, Italy), A. Petti (Salerno, Italy), G. Caliendo (Napoli, Italy), F. Roviezzo (Napoli, Italy)
Congress or journal article abstractWebcastPDF journal article, handout or slidesE-poster
Congress or journal article abstractWebcastPDF journal article, handout or slidesE-poster
THE PDE4 INHIBITOR TANIMILAST SHOWS DISTINCT IMMUNOMODULATORY PROPERTIES ASSOCIATED WITH A TYPE 2 ENDOTYPE AND CD141 UPREGULATION
H. Nguyen (Brescia (BS), Italy), V. Salvi (Brescia (BS), Italy), L. Tiberio (Brescia (BS), Italy), M. Govoni (Parma (PR), Italy), G. Villetti (Parma (PR), Italy), M. Civelli (Parma (PR), Italy), I. Barbazza (Brescia (BS), Italy), C. Gaudenzi (Brescia (BS), Italy), M. Passari (Brescia (BS), Italy), T. Schioppa (Brescia (BS), Italy), F. Sozio (Brescia (BS), Italy), A. Dal Prete (Brescia (BS), Italy), S. Sozzani (Rome (RM), Italy), D. Bosisio (Brescia (BS), Italy), F. Facchinetti (Parma (PR), Italy)
Congress or journal article abstractWebcastPDF journal article, handout or slidesE-poster
Congress or journal article abstractWebcastPDF journal article, handout or slidesE-poster