Basic science of respiratory infection

Thematic Poster
Chairs: J. Chalmers (Dundee (Angus), United Kingdom), G. Rohde (Frankfurt am Main, Germany)

Non-typeable Haemophilus influenzae activates respiratory epithelial cell innate immune responses independently of intracellular internalisation T. Hinks (Oxford, United Kingdom), M. Brown (Oxford, United Kingdom), S. Morgan (Oxford, United Kingdom), G. Donachie (Oxford, United Kingdom), I. Pavord (Oxford, United Kingdom), C. Arancibia (Oxford, United Kingdom)
Acute lung inflammation in mice by inhaled aerosolized LPS:  effects of various forms of human alpha1-antitrypsin K. Sivaraman (Hannover, Germany), S. Wrenger (Hannover, Germany), D. Schaudien (Hannover, Germany), C. Hesse (Hannover, Germany), K. Sewald (Hannover, Germany), T. Welte (Hannover, Germany), S. Janciauskiene (Hannover, Germany)
Mucosal administration of anti-bacterial antibody (Ab) provides long-term cross-protection against Pseudomonas aeruginosa respiratory infection A. Pitiot (Tours, France), M. Ferreira (Tours, France), C. Parent (Tours, France), C. Boisseau (Tours, France), M. Cortes (Tours, France), L. Bouvart (Tours, France), N. Aubrey (Tours, France), C. Paget (Tours, France), N. Heuzé-Vourc'H (Tours, France), T. Secher (Tours, France)
Lack of S100A9 aggravates pneumococcal pneumonia in mice L. Ostermann (Hannover, Germany), K. Katsarou (Hannover, Germany), R. Maus (Hannover, Germany), M. Christmann (Hannover, Germany), K. Neumann (Hannover, Germany), K. Brand (Hannover, Germany), B. Seeliger (Hannover, Germany), F. Bühling (Dresden, Germany), D. Viemann (Hannover, Germany), T. Welte (Hannover, Germany), U. Maus (Hannover, Germany)
The airway metagenome in Pseudomonas aeruginosa associated severe asthma F. Ivan (Singapore, Singapore), P. Tiew* (Singapore, Singapore), K. Thng (Singapore, Singapore), T. Jaggi (Singapore, Singapore), E. Hwee (Singapore, Singapore), O. How (Singapore, Singapore), J. Abisheganaden (Singapore, Singapore), M. Koh (Singapore, Singapore), S. Chotirmall (Singapore, Singapore)
Triple combinations of ferulic acid, quercetin and glycyrrhizic acid inhibit influenza virus H5N1 hemagglutinin-induced acute lung injure by targeting Janus tyrosine kinase 3 and cAMP-dependent CFTR channel C. Ke (Jinzhou, China), W. Yansheng (Guangzhou, China), S. Qiang (Guangzhou, China), X. Jun (Guangzhou, China)
Histone deacetylase-6 (HDAC6) promotes protective responses during murine influenza A virus (IAV) infection K. Daly (Newcastle, Australia), A. Hsu (Singapore, Singapore), K. Nichol (Newcastle, Australia), J. Horvat (Newcastle, Australia), J. Mayall (Newcastle, Australia), P. Hansbro (Sydney, Australia), P. Wark (Sydney, Australia)
Effect of novel LasB inhibitor ANT3273 on activation of IL-1ß in macrophage and mouse Pseudomonas aeruginosa infection models M. Everett (Labege, France), N. Sprynski (Labege, France), L. Doris (Atlanta, United States), L. Christopher (Atlanta, United States), M. Zalacain (Labege, France)
IL-4 levels in sputum correlate with increased mucus production and ciliary dysfunction E. Cant (Dundee, United Kingdom), M. Bottier (Dundee, United Kingdom), M. Shuttleworth (Dundee, United Kingdom), F. Daudvohra (London, United Kingdom), R. Urquhart (Dundee, United Kingdom), A. Gilmour (Dundee, United Kingdom), M. Crichton (Dundee, United Kingdom), D. Cassidy (Dundee, United Kingdom), T. Burgoyne (London, United Kingdom), C. Hogg (London, United Kingdom), J. Huang (Dundee, United Kingdom), J. Chalmers (Dundee, United Kingdom), A. Shoemark (Dundee, United Kingdom)
The influence of the storage medium on respiratory ciliary beating N. Bricmont (Liège, Belgium), R. Bonhiver (Liège, Belgium), L. Benchimol (Liège, Belgium), A. Poirrier (Liège, Belgium), P. Lefèbvre (Liège, Belgium), R. Louis (Liège, Belgium), M. Seghaye (Liège, Belgium), C. Kempeneers (Liège, Belgium)
Crucial role of iron metabolism in determining outcomes of influenza A virus infection and disease J. Mayall (Newcastle, Australia), A. Pillar (Newcastle, Australia), K. Daly (Newcastle, Australia), A. Brown (Newcastle, Australia), A. Essilfie (Brisbane, Australia), H. Gomez (Newcastle, Australia), R. Kim (Sydney, Australia), K. Nichol (Newcastle, Australia), C. Donovan (Sydney, Australia), G. Anderson (Brisbane, Australia), D. Frazer (Brisbane, Australia), E. Milward (Newcastle, Australia), P. Hansbro (Sydney, Australia), D. Reid (Brisbane, Australia), A. Hsu (Singapore, Singapore), P. Wark (Newcastle, Australia), J. Horvat (Newcastle, Australia)
Clinically relevant administration of naive and activated mesenchymal stromal cells for the treatment of bacterial induced pulmonary sepsis D. Byrnes (Galway (County Galway), Ireland), C. Masterson (Galway (County Galway), Ireland), H. Gonzalez (Galway (County Galway), Ireland), S. Mccarthy (Galway (County Galway), Ireland), D. O'Toole (Galway (County Galway), Ireland), J. Laffey (Galway (County Galway), Ireland)
LSC - 2022 - Identification of a host antiviral and anti-inflammatory metabolite that protects against influenza virus-driven morbidity and mortality A. Cezard (Tours, France), D. Brea-Diakite (Tours, France), V. Vasseur (Tours, France), L. Gonzales (Tours, France), R. Le Goffic (Jouy-en-Josas, France), B. Da Costa (Jouy-en-Josas, France), D. Fouquenet (Tours, France), T. Baranek (Tours, France), C. Paget (Tours, France), A. Guillon (Tours, France), M. Si-Tahar (Tours, France)
A phage cocktail against Pseudomonas aeruginosa lung infection: results from experimental studies M. Brack (Berlin, Germany), M. Vollgraf (Berlin, Germany), G. Nouailles (Berlin, Germany), I. Korf (Braunschweig, Germany), S. Wienecke (Braunschweig, Germany), A. Dannheim (Braunschweig, Germany), H. Ziehr (Braunschweig, Germany), J. Bushe (Berlin, Germany), A. Voss (Berlin, Germany), A. Gruber (Berlin, Germany), A. Hocke (Berlin, Germany), S. Hippenstiel (Berlin, Germany), M. Toennies (Berlin, Germany), J. Lienau (Berlin, Germany), M. Rohde (Braunschweig, Germany), C. Rohde (Braunschweig, Germany), S. Wienhold (Berlin, Germany), M. Witzenrath (Berlin, Germany)
Delayed immunological reaction of Human Microvascular Lung Endothelium in response to Human Coronavirus 229E infection. R. Szewczyk (Lódz, Poland), M. Gawrysiak (Lódz, Poland), A. Gajewski (Lódz, Poland), M. Chalubinski (Lódz, Poland)
Late Breaking Abstract - Nebulized mesenchymal stem cells derived conditioned media retains the capacity to mitigate lung injury in vivo. H. Gonzalez Esteban (Galway, Ireland), S. Mccarthy (Galway, Ireland), C. Masterson (Galway, Ireland), D. Byrnes (Galway, Ireland), R. Macloughlin (Galway, Ireland), J. Laffey (Galway, Ireland), D. O'Toole (Galway, Ireland)
Late Breaking Abstract - Single cell transcriptomic dissection of virus induced immunopathology in interferon gamma receptor null mice L. Yang (Munich, Germany), L. Heumos (Munich, Germany), I. Angelidis (Munich, Germany), M. Ansari (Munich, Germany), S. Zhou (Munich, Germany), C. H. Mayer (Munich, Germany), L. M. Simon (Munich, Germany), M. Strunz (Munich, Germany), F. J. Theis (Munich, Germany), H. Adler (Munich, Germany), H. Schiller (Munich, Germany)
Molecular characterisation of COPD exacerbations H. Keir (Dundee (Angus), United Kingdom), H. Richardson (Dundee (Angus), United Kingdom), A. Veluchamy (Dundee (Angus), United Kingdom), D. Alferes De Lima (Dundee (Angus), United Kingdom), A. Gilmour (Dundee (Angus), United Kingdom), C. Hennayake (Dundee (Angus), United Kingdom), A. Dicker (Dundee (Angus), United Kingdom), M. Crichton (Dundee (Angus), United Kingdom), J. Chalmers (Dundee (Angus), United Kingdom)