February

COPD frequent exacerbators: time for the recycle bin? Robert A. Stockley Eur Respir J, 57 (2) 2003758; 10.1183/13993003.03758-2020
The patient tells it! The importance of patient's quality of life perception in pulmonary arterial hypertension risk assessment Silvia Ulrich, Ekkehard Grunig Eur Respir J, 57 (2) 2004376; 10.1183/13993003.04376-2020
Preventing cardiovascular events after pneumonia with aspirin: one step forward, but still many to go Martin Kolditz, Tobias Welte Eur Respir J, 57 (2) 2003778; 10.1183/13993003.03778-2020
Honing in on the effectors of oxidative stress in the asthmatic lung: oxidised phosphatidylcholines Raymond B. Penn Eur Respir J, 57 (2) 2003736; 10.1183/13993003.03736-2020
The case of methotrexate and the lung: Dr Jekyll and Mr Hyde Vincent Cottin, Elizabeth Bendstrup, Philippe Bonniaud, Mouhamad Nasser, Paolo Spagnolo, Claudia Valenzuela, Martin Kolb Eur Respir J, 57 (2) 2100079; 10.1183/13993003.00079-2021
Noninvasive strategies in COVID-19: epistemology, randomised trials, guidelines, physiology Martin J. Tobin, Amal Jubran, Franco Laghi Eur Respir J, 57 (2) 2004247; 10.1183/13993003.04247-2020
European Respiratory Society statement on sleep apnoea, sleepiness and driving risk Maria R. Bonsignore, Winfried Randerath, Sofia Schiza, Johan Verbraecken, Mark W. Elliott, Renata Riha, Ferran Barbe, Izolde Bouloukaki, Alessandra Castrogiovanni, Oana Deleanu, Marta Goncalves, Damien Leger, Oreste Marrone, Thomas Penzel, Silke Ryan, Dan Smyth, Joaquin Teran-Santos, Cecilia Turino, Walter T. McNicholas Eur Respir J, 57 (2) 2001272; 10.1183/13993003.01272-2020
Osteoporosis and fracture risk associated with inhaled corticosteroid use among Swedish COPD patients: the ARCTIC study Christer Janson, Karin Lisspers, Björn Ställberg, Gunnar Johansson, Florian S. Gutzwiller, Karen Mezzi, Linda Mindeholm, Bine Kjoeller Bjerregaard, Leif Jorgensen, Kjell Larsson Eur Respir J, 57 (2) 2000515; 10.1183/13993003.00515-2020
Should the number of acute exacerbations in the previous year be used to guide treatments in COPD? Mohsen Sadatsafavi, James McCormack, John Petkau, Larry D. Lynd, Tae Yoon Lee, Don D. Sin Eur Respir J, 57 (2) 2002122; 10.1183/13993003.02122-2020
EmPHasis-10 health-related quality of life score predicts outcomes in patients with idiopathic and connective tissue disease-associated pulmonary arterial hypertension: results from a UK multicentre study Robert A. Lewis, Iain Armstrong, Carmel Bergbaum, Melanie J. Brewis, John Cannon, Athanasios Charalampopoulos, A. Colin Church, J. Gerry Coghlan, Rachel J. Davies, Konstantinos Dimopoulos, Charlie Elliot, J. Simon R. Gibbs, Wendy Gin-Sing, Gulam Haji, Abdul G. Hameed, Luke S. Howard, Martin K. Johnson, Aleksander Kempny, David G. Kiely, Francesco Lo Giudice, Colm McCabe, Andrew J. Peacock, Oyinkansola Peleyeju, Joanna Pepke-Zaba, Gary Polwarth, Laura Price, Ian Sabroe, Benjamin E. Schreiber, Karen Sheares, Dolores Taboada, A.A. Roger Thompson, Mark R. Toshner, Ivy Wanjiku, S. John Wort, Janelle Yorke, Robin Condliffe Eur Respir J, 57 (2) 2000124; 10.1183/13993003.00124-2020
EmPHasis-10 as a measure of health-related quality of life in pulmonary arterial hypertension: data from PHAR Marissa Borgese, David Badesch, Todd Bull, Murali Chakinala, Teresa DeMarco, Jeremy Feldman, H. James Ford, Dan Grinnan, James R. Klinger, Lena Bolivar, Oksana A. Shlobin, Robert P. Frantz, Jeffery S. Sager, Stephen C. Mathai, Steven Kawut, Peter J. Leary, Michael P. Gray, Rita A. Popat, Roham T. Zamanian Eur Respir J, 57 (2) 2000414; 10.1183/13993003.00414-2020
Aspirin reduces cardiovascular events in patients with pneumonia: a prior event rate ratio analysis in a large primary care database Fergus Hamilton, David Arnold, William Henley, Rupert A. Payne Eur Respir J, 57 (2) 2002795; 10.1183/13993003.02795-2020
The cost-effectiveness of azithromycin in reducing exacerbations in uncontrolled asthma Ciaran O'Neill, Peter G. Gibson, Liam G. Heaney, John W. Upham, Ian A. Yang, Paul N. Reynolds, Sandra Hodge, Christine R. Jenkins, Matthew Peters, Guy B. Marks, Alan L. James, Jodie L. Simpson Eur Respir J, 57 (2) 2002436; 10.1183/13993003.02436-2020
Allergen inhalation generates pro-inflammatory oxidised phosphatidylcholine associated with airway dysfunction Christopher D. Pascoe, Aruni Jha, Min Hyung Ryu, Mirna Ragheb, Jignesh Vaghasiya, Sujata Basu, Gerald L. Stelmack, Sadeesh Srinathan, Biniam Kidane, Jason Kindrachuk, Paul M. O'Byrne, Gail M. Gauvreau, Amir Ravandi, Christopher Carlsten, Andrew J. Halayko Eur Respir J, 57 (2) 2000839; 10.1183/13993003.00839-2020
Periostin: contributor to abnormal airway epithelial function in asthma? Janette K. Burgess, Marnix R. Jonker, Marijn Berg, Nick T.H. ten Hacken, Kerstin B. Meyer, Maarten van den Berge, Martijn C. Nawijn, Irene H. Heijink Eur Respir J, 57 (2) 2001286; 10.1183/13993003.01286-2020
Methotrexate and rheumatoid arthritis associated interstitial lung disease Pierre-Antoine Juge, Joyce S. Lee, Jessica Lau, Leticia Kawano-Dourado, Jorge Rojas Serrano, Marco Sebastiani, Gouri Koduri, Eric Matteson, Karina Bonfiglioli, Marcio Sawamura, Ronaldo Kairalla, Lorenzo Cavagna, Emanuele Bozzalla Cassione, Andreina Manfredi, Mayra Mejia, Pedro Rodríguez-Henriquez, Montserrat I. González-Pérez, Ramcés Falfán-Valencia, Ivette Buendia-Roldán, Gloria Pérez-Rubio, Esther Ebstein, Steven Gazal, Raphaël Borie, Sébastien Ottaviani, Caroline Kannengiesser, Benoît Wallaert, Yurdagul Uzunhan, Hilario Nunes, Dominique Valeyre, Nathalie Saidenberg-Kermanac'h, Marie-Christophe Boissier, Lidwine Wemeau-Stervinou, René-Marc Flipo, Sylvain Marchand-Adam, Pascal Richette, Yannick Allanore, Claire Dromer, Marie-Elise Truchetet, Christophe Richez, Thierry Schaeverbeke, Huguette Lioté, Gabriel Thabut, Kevin D. Deane, Joshua J. Solomon, Tracy Doyle, Jay H. Ryu, Ivan Rosas, V. Michael Holers, Catherine Boileau, Marie-Pierre Debray, Raphaël Porcher, David A. Schwartz, Robert Vassallo, Bruno Crestani, Philippe Dieudé Eur Respir J, 57 (2) 2000337; 10.1183/13993003.00337-2020
Progressive fibrosing interstitial lung disease: a clinical cohort (the PROGRESS study) Mouhamad Nasser, Sophie Larrieu, Salim Si-Mohamed, Kaïs Ahmad, Loic Boussel, Marie Brevet, Lara Chalabreysse, Céline Fabre, Sébastien Marque, Didier Revel, Françoise Thivolet-Bejui, Julie Traclet, Sabrina Zeghmar, Delphine Maucort-Boulch, Vincent Cottin Eur Respir J, 57 (2) 2002718; 10.1183/13993003.02718-2020
Using joint modelling to assess the association between a time-varying biomarker and a survival outcome: an illustrative example in respiratory medicine Yuntao Chen, Douwe Postmus, Martin R. Cowie, Holger Woehrle, Karl Wegscheider, Anita K. Simonds, Marike Boezen, Virend K. Somers, Helmut Teschler, Christine Eulenburg Eur Respir J, 57 (2) 2003206; 10.1183/13993003.03206-2020
Efficacy of elexacaftor/tezacaftor/ivacaftor in patients with cystic fibrosis and advanced lung disease Kate M. O'Shea, Orla M. O'Carroll, Catherine Carroll, Brenda Grogan, Anna Connolly, Lynda O'Shaughnessy, Trevor T. Nicholson, Charles G. Gallagher, Edward F. McKone Eur Respir J, 57 (2) 2003079; 10.1183/13993003.03079-2020
Reversible pulmonary hypertension associated with multivisceral Whipple's disease Alice Camboulive, Etienne-Marie Jutant, Laurent Savale, Xavier Jaïs, Olivier Sitbon, Charlotte Mussini, Jérémie Bénichou, Jean-Christophe Lagier, Marc Humbert, David Montani Eur Respir J, 57 (2) 2003132; 10.1183/13993003.03132-2020
Residual symptoms and lower lung function in patients recovering from SARS-CoV-2 infection Frederik Trinkmann, Michael Müller, Alexandra Reif, Nicolas Kahn, Michael Kreuter, Franziska Trudzinski, Monika Eichinger, Claus-Peter Heussel, Felix J.F. Herth Eur Respir J, 57 (2) 2003002; 10.1183/13993003.03002-2020
Continuous positive airway pressure in COVID-19 patients with moderate-to-severe respiratory failure Claudia Brusasco, Francesco Corradi, Antonia Di Domenico, Francesca Raggi, Graziano Timossi, Gregorio Santori, Vito Brusasco Eur Respir J, 57 (2) 2002524; 10.1183/13993003.02524-2020
Mitigating increased variability of multiple breath washout indices due to tidal breathing Sylvia Verbanck, Daniel Schuermans, Manuel Paiva, Paul D. Robinson, Eef Vanderhelst Eur Respir J, 57 (2) 2002765; 10.1183/13993003.02765-2020
Budesonide–formoterol reliever therapy in intermittent versus mild persistent asthma Alberto Papi, Irene Braithwaite, Stefan Ebmeier, Robert J. Hancox, Tim Harrison, Mark Holliday, Claire Houghton, Luca Morandi, Karen Oldfield, Ian D. Pavord, Helen K. Reddel, Mathew Williams, Mark Weatherall, Richard Beasley Eur Respir J, 57 (2) 2003064; 10.1183/13993003.03064-2020
Safety and efficacy of pirfenidone and nintedanib in patients with idiopathic pulmonary fibrosis and carrying a telomere-related gene mutation Aurélien Justet, Dymph Klay, Raphaël Porcher, Vincent Cottin, Kais Ahmad, Maria Molina Molina, Hilario Nunes, Martine Reynaud-Gaubert, Jean Marc Naccache, Effrosyni Manali, Antoine Froidure, Stéphane Jouneau, Lidwine Wemeau, Claire Andrejak, Anne Gondouin, Sandrine Hirschi, Elodie Blanchard, Benjamin Bondue, Philippe Bonniaud, Cécile Tromeur, Grégoire Prévot, Sylvain Marchand-Adam, Manuela Funke-Chambour, Anne Sophie Gamez, Ibrahima Ba, Spyridon Papiris, Jan Grutters, Bruno Crestani, Coline van Moorsel, Caroline Kannengiesser, Raphaël Borie Eur Respir J, 57 (2) 2003198; 10.1183/13993003.03198-2020
Breath volatile organic compounds and inflammatory markers in adult asthma patients: negative results from the ALLIANCE cohort Olaf Holz, Benjamin Waschki, Henrik Watz, Anne Kirsten, Mustafa Abdo, Frauke Pedersen, Markus Weckmann, Oliver Fuchs, Anna-Maria Dittrich, Gesine Hansen, Matthias V. Kopp, Erika von Mutius, Klaus F. Rabe, Jens M. Hohlfeld, Thomas Bahmer Eur Respir J, 57 (2) 2002127; 10.1183/13993003.02127-2020
mTORC1 hyperactivation in lymphangioleiomyomatosis leads to ACE2 upregulation in type II pneumocytes: implications for COVID-19 Yan Tang, David J. Kwiatkowski, Elizabeth P. Henske Eur Respir J, 57 (2) 2002737; 10.1183/13993003.02737-2020
Ethical obligations for supporting healthcare workers during the COVID-19 pandemic Alexander Supady, J. Randall Curtis, Crystal E. Brown, Daniel Duerschmied, Lyn Anne von Zepelin, Marc Moss, Daniel Brodie Eur Respir J, 57 (2) 2100124; 10.1183/13993003.00124-2021
Comment on: Bronchoalveolar lavage fluid lymphocytosis in chronic hypersensitivity pneumonitis: a systematic review and meta-analysis Onofre Moran-Mendoza, Mohamed Khalil Eur Respir J, 57 (2) 2004347; 10.1183/13993003.04347-2020
Reply: BAL lymphocyte percentage is as good as the company it keeps Nicola Adderley, Christopher J. Humphreys, Hayley Barnes, Zahra A. Premji, Kerri A. Johannson Eur Respir J, 57 (2) 2100092; 10.1183/13993003.00092-2021