Basic science

COVID-19
Chairs: C. Brightling (Leicester (Leicestershire), United Kingdom)
Aims: This session will explain the basic science behind the SARS CoV 2 virus, covering factors from the structure, viral entry, genomic epidemiology, immune response, and lung effects. Key references: 1: McCallum M, Walls AC, Bowen JE, Corti D, Veesler D. Structure-guided covalent stabilization of coronavirus spike glycoprotein trimers in the closed conformation. Nat Struct Mol Biol. 2020 Aug 4. doi: 10.1038/s41594-020-0483-8.Epub ahead of print. PMID: 32753755. 2: Walls AC, Park YJ, Tortorici MA, Wall A, McGuire AT, Veesler D. Structure, Function, and Antigenicity of the SARS-CoV-2 Spike Glycoprotein. Cell. 2020 Apr 16;181(2):281-292.e6. doi: 10.1016/j.cell.2020.02.058. Epub 2020 Mar 9. PMID:32155444; PMCID: PMC7102599.

Virus biology (structure, viral entry and genomic epidemiology of virus) M. Koopmans (Rotterdam, Netherlands)
Host response (immune response) T. Hussell (Manchester (Greater Manchester), United Kingdom)
Host response (airway/lung effects) G. Jenkins (Nottingham (Nottinghamshire), United Kingdom)