Closing the gap: novel translational research strategies

Symposium
Chairs: Reinoud Gosens (Groningen, Netherlands), Maria Gabriela Belvisi (London, United Kingdom)
Aims: This session will explain why respiratory research in 2016 will need innovation in translational models of disease. Specific examples of how innovations in translational models of disease have helped to close knowledge gaps between basic and clinical respiratory research will be provided. How organoids, 3-dimensonal in vitro models, and the lung slice technique can be used in respiratory research to elucidate mechanisms of disease will be described.
How organoids helped to discover cystic fibrosis transmembrane conductance regulator (CFTR) therapeutics and predict response to treatment
Jeffrey M. Beekman (Utrecht, Netherlands)
WebcastSlide presentation
WebcastSlide presentation
3-dimensional airway models reveal airway epithelial responses to mechanical stretch and compression
Christopher Grainge (Newscastle, Australia)
WebcastSlide presentation
WebcastSlide presentation
Translational models in asthma and COPD
Tania Maes (Ghent, Belgium)
WebcastSlide presentation
WebcastSlide presentation