Translational models of disease

Thematic Poster Session
Chairs: P. Kirkham (London, United Kingdom), K. Tomita (Osakasayama, Japan), Z. Diamant (Rotterdam, Netherlands)

Transient receptor potential ankyrin 1 (TRPA1)-mediated cough M. Brozmanova, L. Mazurova, F. Ru, M. Tatar, M. Kollarik (Martin, Slovakia; Baltimore, United States Of America)
Toxicity and safety of dextromethorphan inhalation in a mouse model prior its use in humans A. Bar-Shai, A. Starr, Y. Schwarz (Tel Aviv, Israel)
Non-genomic effect of glucocorticoids on inhibition of expression of CD63 on peripheral blood basophils K. Tomita, H. Zushi, N. Watatani, S. Yamagata, H. Ichihashi, R. Satoh, H. Sano, H. Kume, R. Haraguchi, Y. Tohda (Osakasayama, Sakai, Japan)
Expression and functionality of P-glycoprotein in human bronchial epithelial cells in vitro V. Hutter, C. Hilgendorf, A. Cooper, V. Zann, D. Pritchard, C. Bosquillon (Nottingham, Leicestershire, United Kingdom; Mölndal, Sweden)
Fluticasone furoate, a novel corticosteroid, maintains glucocorticoid receptor nuclear localisation for 24 hours after washout in monocytes A. Hakim, M. Johnson, P. Barnes, I. Adcock, O. Usmani (London, United Kingdom)
Roflumilast N-oxide, a selective PDE4 inhibitor, curbs platelet-leukocyte interactions L. Totani, A. Piccoli, C. Amore, A. Di Santo, N. Martelli, G. Dell‘Elba, V. Evangelista (Santa Maria Imbaro, Italy)
A-kinase anchoring proteins as novel regulators of airway smooth muscle function W. J. Poppinga, A. Oldenburger, W. Timens, P. Skroblin, E. Klussmann, H. Meurs, M. Schmidt, H. Maarsingh (Groningen, Netherlands; Berlin, Germany)
Bosentan is superior to ambrisentan in reducing the expression of asthma- and COPD-related cytokines J. Knobloch, Y. Lin, D. Jungck, K. Urban, J. Strauch, E. Stoelben, J. Behr, A. Koch (Bochum, Cologne, Germany)
Simvastatin selectively inhibits TSLP-production in primary bronchial epithelial cells from COPD donors A. Brandelius, J. Calvén, L. Bjermer, I. Mahmutovic Persson, C. Persson, M. Andersson, L. Uller (Lund, Sweden)
Effects of corticosteroid or montelukast associated to iNOS inhibitior on inflammation and remodelling of distal lung in animals with chronic inflammation F. C. R. de Souza, N. B. Gobbato, C. M. Prado, E. A. Leick, M. de Arruda Martins, I. de Fátima Lopes Calvo Tibério (São Paulo, Diadema, Brazil)
The effect of the different methanolic extracts of nigella sativa on tracheal responsiveness of guinea-pigs R. Keyhanmanesh, H. Bagban, M. R. Alipour, F. Mirzaei Bavil, M. Ahmady, M. A. Ebrahimi Sadatloo (Tabriz, Islamic Republic Of Iran)
Effects of aclidinium on cigarette smoke-induced fibroblast activation in vitro J. Milara, T. Peiró, A. Serrano, J. Gustavo, A. Gavaldà, M. Miralpeix, E. Morcillo, J. Cortijo (Valencia, Barcelona, Spain)
Effects of aclidinium on airway remodelling in guinea pigs chronically exposed to cigarette smoke D. Domínguez-Fandos, R. Puig-Pey, E. Ferrer, C. Carreño, M. Aparici, J. Beleta, N. Prats, M. Miralpeix, A. Gavaldà, V. I. Peinado, J. A. Barberà (Barcelona, Spain)
Effects of aclidinium on respiratory function in guinea pigs chronically exposed to cigarette smoke E. Ferrer, D. Domínguez-Fandos, R. Puig-Pey, C. Carreño, M. Aparici, J. Beleta, N. Prats, A. Gavaldà, M. Miralpeix, V. I. Peinado, J. A. Barberà (Barcelona, Spain)
Protective effect of lecithinized superoxide dismutase (PC-SOD) againast elastase-induced pulmonary emphysema in mice K. I. Tanaka, T. Mizushima (Kumamoto, Japan)
Prevention of adverse pulmonary consequences of myocardial ischaemia in rats F. Petak, G. Albu, E. Lele, M. Beghetti, W. Habre (Szeged, Hungary; Geneva, Switzerland)
Can streptomycin prevent the selection of isoniazid-resistant mutants in nude mice infected with M. tuberculosis? C. Andrejak, S. Tyagi, E. Nuermberger, J. Grosset (Baltimore, United States Of America)
Soluble guanylate cyclase stimulator riociguat prevents fibrotic tissue remodeling and improves survival in salt-sensitive Dahl rats J. P. Stasch, S. Geschka, B. Lawrenz, Y. Sharkovska, B. Hocher, O. V. Evgenov, A. Kretschmer (Wuppertal, Berlin, Germany; Boston, United States Of America)
AZD3199: A fast acting β2-receptor agonist with a long duration of action A. Young, R. Bonnert, E. Cadogan, S. Connolly, P. Gardiner, S. Jordan, D. Nicholls, S. Paine, G. Pairaudeau, M. Stocks (Loughborough, United Kingdom)
An assessment of the functional profile of aclidinium in human bronchi and left atria J. Milara, E. Gabarda, A. Gavaldà, M. Miralpeix, J. Beleta, E. Morcillo, J. Cortijo (Valencia, Barcelona, Spain)