LATE-BREAKING ABSTRACT: Long-term efficacy of A1-PI therapy in RAPID and RAPID extension trials
Noel Gerard McElvaney (Dublin, Ireland), N. Gerard McElvaney, Kenneth R. Chapman, Jonathan Burdon, Eeva Piitulainen, Niels Seersholm, James Stocks, Robert Sandhaus, Oliver Vit, Michael Fries, Jonathan M. Edelman
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LATE-BREAKING ABSTRACT: Anti-inflammatory effect of RP6557, a dual PI3K d/? inhibitor, in glucocorticoid insensitive human neutrophils from chronic obstructive pulmonary disease patients
Xavier Milara (Valencia, Spain), Javier Milara, Adela Serrano, Julio Cortijo, Srikant Viswanadha, Swaroop Vakkalanka
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LATE-BREAKING ABSTRACT: Reslizumab in patients with late-onset asthma with elevated blood eosinophils
Guy Brusselle (Ghent, Belgium), Guy Brusselle, Matthew Germinaro, Sherrine Eid, James Zangrilli
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LATE-BREAKING ABSTRACT: A novel role for CCR3 in promoting airways hyperreactivity; Role for CCR3-muscarinic M3 receptor heterodimers
Kevin Bacon (San Diego, United States of America), Kevin Bacon, Emma Moss, Karen Bingham, Louis-Philippe Boulet, Mark Fitzgerald, Gail Gauvreau, Paul O²Byrne, Taylor Gilliland, Tracy Handel, Tai-Wei Ly, Stefen Boehme
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LATE-BREAKING ABSTRACT: A dose-ranging study of dupilumab in patients (pts) with uncontrolled asthma despite use of inhaled corticosteroids plus a long-acting beta-agonist (ICS/LABA): Final data
Sally Wenzel (Pittsburgh, United States of America), Sally Wenzel, Mario Castro, Bingzhi Zhang, Gianluca Pirozzi, E. Rand Sutherland, Neil Graham, Robert R. Evans, Mariana Louis-Tisserand, Ariel Teper
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LATE-BREAKING ABSTRACT: Effect of QAW039, an oral prostaglandin D2 receptor (DP2/CRTh2) antagonist, upon bronchial epithelial integrity in treatment-resistant asthma in a randomized, placebo controlled study
Rachid Berair (Birmingham, United Kingdom), Rachid Berair, Sherif Gonem, Amisha Singapuri, Ruth Hartley, Marie Laurencin, Gerald Bacher, Bjoern Holzhauer, Michelle Bourne, Vijay Mistry, Ian Pavord, Adel Mansur, Andrew Wardlaw, Salman Siddiqui, Richard Kay, Chris Brightling
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LATE-BREAKING ABSTRACT: Transcriptomic fingerprinting in severe adult-onset asthma shows type2-high and inflammatory-cell gene signatures in the U-BIOPRED cohort
Pieter-Paul Hekking (Amsterdam, Netherlands), P.P. Hekking, M.J. Loza, S. Pavlidis, B. De Meulder, F. Baribaud, C. Auffray, A.H. Wagener, A.T. Bansal, A.R. Sousa, J. Corfield, E.H. Bel, I.M. Adcock, K.F. Chung, R. Djukanovic, P.J. Sterk
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LATE-BREAKING ABSTRACT: Oxidation of the alarmin IL-33 regulates ST2-dependent inflammation
Suzanne Cohen (Cambridge, United Kingdom), Suzanne Cohen, Ian Scott, Jayesh Majithiya, Laura Rapley, Benjamin Kemp, Nicholas Bond, Dorothy Sims, Christopher Brightling, Robin Butler, Daniel Higazi, Dominic Corkill, Richard May, Tomas Mustelin, Matthew Sleeman
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