European Respiratory Society Monograph, Vol. 94. 2021
ISBN (electronic): 978-1-84984-149-8
DOI: 10.1183/2312508X.erm9421
The story of COVID-19 now seems so familiar: from the first reported case of a new respiratory infection in China in December 2019, to a pandemic that rapidly changed the world. Respiratory clinicians and scientists were at the forefront of delivering healthcare for people with COVID-19, leading efforts to understand this novel virus and disease, and developing and testing strategies to better prevent and treat it. These endeavours extended not only to the acute illness, but also to understanding the longer-term consequences. The pace of knowledge acquisition was rapid but is now maturing. This Monograph therefore provides a timely and valuable state-of-the-art summary for clinicians and scientists on our understanding of this virus and its consequences to date. It is essential reading for all those involved in the care of people who are or who have been affected by COVID-19.
Preface Anh Tuan Dinh-Xuan Eur Respir Monogr 2021; 94: v-vi |  |
Guest Editors
Eur Respir Monogr 2021; 94: vii-viii |  |
Introduction Aurelie Fabre, John R. Hurst, Sheila Ramjug Eur Respir Monogr 2021; 94: ix-xii |   |
List of abbreviations
Eur Respir Monogr 2021; 94: xiv |  |
Respiratory failure in COVID-19: a patient's perspective and clinical cases Francesco Amati, Annalisa Vigni, Sofia Misuraca, Francesco Bindo, Andrea Gramegna, Antonio Voza, Francesco Blasi, Stefano Aliberti Eur Respir Monogr 2021; 94: 1-13 |   |
Epidemiology of COVID-19: global spread, risk factors for disease incidence, severity and mortality Joan B. Soriano, Alberto Infante Eur Respir Monogr 2021; 94: 14-27 |   |
Historical perspective: other human coronavirus infectious diseases, SARS and MERS David S. Hui, Alimuddin Zumla Eur Respir Monogr 2021; 94: 28-38 |   |
Drug repurposing and other strategies for rapid coronavirus antiviral development: lessons from the early stage of the COVID-19 pandemic Sophie O'Reilly, Matthew Angeliadis, Ross Murtagh, Virginie W. Gautier Eur Respir Monogr 2021; 94: 39-68 |   |
Can the immune system be targeted to treat COVID-19? Sarah Abdelhafeez, Derek Doherty Eur Respir Monogr 2021; 94: 69-85 |   |
Lung pathology in COVID-19 Marie-Christine Copin, Jean-Baptiste Gibier, Véronique Hofman, Paul Hofman Eur Respir Monogr 2021; 94: 86-100 |   |
Clinical features and acute management of COVID-19 in adults Nuzhath Khan, Lucy Lamb, Rachel Moores Eur Respir Monogr 2021; 94: 101-123 |   |
COVID-19: management in the ICU Sachin Ananth, Avinash Aujayeb, Shari B. Brosnahan, Lieuwe D. Bos, Rebecca F. D'Cruz, Daniel López-Padilla, Anthony Lubinsky, Hrishikesh S. Kulkarni, Toni Marín, Ema Swingwood Eur Respir Monogr 2021; 94: 124-143 |   |
Clinical features and acute management of COVID-19 in children Katherine Longbottom, Elizabeth Whittaker, Justin Penner Eur Respir Monogr 2021; 94: 144-161 |   |
COVID-19: imaging Christian B. Laursen, Helmut Prosch, Stefan M.W. Harders, Casper Falster, Jesper R. Davidsen, Ádám D. Tárnoki Eur Respir Monogr 2021; 94: 162-179 |   |
Post-COVID-19 sequelae Andrea Gramegna, Marco Mantero, Francesco Amati, Stefano Aliberti, Francesco Blasi Eur Respir Monogr 2021; 94: 180-196 |   |
Post-COVID-19 rehabilitation Sally Singh Eur Respir Monogr 2021; 94: 197-213 |   |
Clinical trials during the COVID-19 pandemic: research design and lessons Hani Abo-Leyah, James D. Chalmers Eur Respir Monogr 2021; 94: 214-231 |   |
Economic, physical and social determinants of health during the COVID-19 lockdown: a call for renewed societal responses Leanna M.W. Lui, Yena Lee, Roger S. McIntyre Eur Respir Monogr 2021; 94: 232-243 |   |
COVID-19 vaccines: immunology, regulation and clinical management Anita K. Simonds, Rosemary J. Boyton Eur Respir Monogr 2021; 94: 244-260 |   |