ERS Monograph - Current issue: Severe asthma

This issue

European Respiratory Society Monograph, Vol. 84. 2019
ISBN (electronic): 978-1-84984-104-7
DOI: 10.1183/2312508X.erm8419

<< Previous issue

This issue

European Respiratory Society Monograph, Vol. 84. 2019
ISBN (electronic): 978-1-84984-104-7
DOI: 10.1183/2312508X.erm8419

<< Previous issue



About this issue

Severe asthma is a form of asthma that responds poorly to currently available medication, and its patients represent those with greatest unmet needs. In the last 10 years, substantial progress has been made in terms of understanding some of the mechanisms that drive severe asthma; there have also been concomitant advances in the recognition of specific molecular phenotypes. This ERS Monograph covers all aspects of severe asthma – epidemiology, diagnosis, mechanisms, treatment and management – but has a particular focus on recent understanding of mechanistic heterogeneity based on an analytic approach using various ‘omics platforms applied to clinically well-defined asthma cohorts. How these advances have led to improved management targets is also emphasised. This book brings together the clinical and scientific expertise of those from around the world who are collaborating to solve the problem of severe asthma.

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 [+]  Full text journal article Preface
John Hurst
Eur Respir Monogr 2019; 84: v
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 [+]  Full text journal article vi Guest Editors
Eur Respir Monogr 2019; 84: vi-viii
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 [+]  Congress or journal article abstract Full text journal article ix Introduction
Kian Fan Chung, Elliot Israel, Peter G. Gibson
Eur Respir Monogr 2019; 84: ix-x
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 [+]  Full text journal article xii List of abbreviations
Eur Respir Monogr 2019; 84: xii
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 [+]  Congress or journal article abstract Full text journal article Definition and impact of severe asthma
William W. Busse
Eur Respir Monogr 2019; 84: 1-15
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 [+]  Congress or journal article abstract Full text journal article 16 Understanding the experience of people living with severe asthma
Vanessa M. McDonald, Erika Kennington, Michael E. Hyland
Eur Respir Monogr 2019; 84: 16-29
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 [+]  Congress or journal article abstract Full text journal article 30 The contribution of comorbidities, psychosocial factors and adherence to the presentation of severe asthma
Mark Hew, Liam G. Heaney
Eur Respir Monogr 2019; 84: 30-47
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 [+]  Congress or journal article abstract Full text journal article 48 Clinical phenotypes of severe asthma: adults
Tae-Bum Kim, Elisabeth H. Bel, Wendy Moore
Eur Respir Monogr 2019; 84: 48-63
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 [+]  Congress or journal article abstract Full text journal article 64 Clinical phenotypes of severe asthma: children
W. Gerald Teague, Graham Roberts
Eur Respir Monogr 2019; 84: 64-81
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 [+]  Congress or journal article abstract 82 Mechanisms underlying fixed airflow obstruction and exacerbations
Katarzyna Duszyk, Peter G. Gibson, Vanessa M. McDonald
Eur Respir Monogr 2019; 84: 82-92
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