Lung cancer in pulmonary fibrosis: no room for nihilism!
Bruno Crestani, Martin Kolb
Eur Respir J, 60 (6) 2201946; 10.1183/13993003.01946-2022 |    |
How a fibroblast ages: a role for bone morphogenetic protein 4 in protecting lung fibroblasts from senescence in pulmonary fibrosis
Laszlo Farkas, Jeffrey C. Horowitz, Ana L. Mora
Eur Respir J, 60 (6) 2201702; 10.1183/13993003.01702-2022 | |
COPD detection in lung cancer screening programmes: “hitting two birds with one stone”
Juan P. de-Torres, Bartolome R. Celli
Eur Respir J, 60 (6) 2201294; 10.1183/13993003.01294-2022 | |
Chymase-1: a “MAST”-er switch in COPD?
Corrine R. Kliment, Reinoud Gosens
Eur Respir J, 60 (6) 2201356; 10.1183/13993003.01356-2022 | |
The SOX17 phenotype in pulmonary arterial hypertension: lessons for pathobiology and clinical management
Jurjan Aman, Nicholas W. Morrell, Christopher J. Rhodes, Martin R. Wilkins, Harm Jan Bogaard
Eur Respir J, 60 (6) 2201438; 10.1183/13993003.01438-2022 | |
A leap towards personalised therapy of acute lung injury
Martin Witzenrath, Tobias Welte
Eur Respir J, 60 (6) 2201808; 10.1183/13993003.01808-2022 | |
Does autonomous macrophage-driven inflammation promote alveolar damage in COVID-19?
David H. Dockrell, Clark D. Russell, Brian McHugh, Rupsha Fraser
Eur Respir J, 60 (6) 2201521; 10.1183/13993003.01521-2022 | |
Contributions to simplifying the global interpretation of spirometry: high quality spirometry data from Asia
Arnulf Langhammer
Eur Respir J, 60 (6) 2201608; 10.1183/13993003.01608-2022 | |
Inspiratory hyperoxia: a new way to prevent metastasis through metabolism reprogramming in non-small cell lung cancer
Beatrice Eymin
Eur Respir J, 60 (6) 2201357; 10.1183/13993003.01357-2022 | |
Nintedanib plus chemotherapy for nonsmall cell lung cancer with idiopathic pulmonary fibrosis: a randomised phase 3 trial
Kohei Otsubo, Junji Kishimoto, Masahiko Ando, Hirotsugu Kenmotsu, Yuji Minegishi, Hidehito Horinouchi, Terufumi Kato, Eiki Ichihara, Masashi Kondo, Shinji Atagi, Motohiro Tamiya, Satoshi Ikeda, Toshiyuki Harada, Shinnosuke Takemoto, Hidetoshi Hayashi, Keita Nakatomi, Yuichiro Kimura, Yasuhiro Kondoh, Masahiko Kusumoto, Kazuya Ichikado, Nobuyuki Yamamoto, Kazuhiko Nakagawa, Yoichi Nakanishi, Isamu Okamoto
Eur Respir J, 60 (6) 2200380; 10.1183/13993003.00380-2022 | |
Bone morphogenetic protein 4 inhibits pulmonary fibrosis by modulating cellular senescence and mitophagy in lung fibroblasts
Ruijuan Guan, Liang Yuan, Jingpei Li, Jian Wang, Ziying Li, Zhou Cai, Hua Guo, Yaowei Fang, Ran Lin, Wei Liu, Lan Wang, Qiuyu Zheng, Jingyi Xu, You Zhou, Jing Qian, Mingjing Ding, Jieping Luo, Yuanyuan Li, Kai Yang, Dejun Sun, Hongwei Yao, Jianxing He, Wenju Lu
Eur Respir J, 60 (6) 2102307; 10.1183/13993003.02307-2021 | |
Detection of COPD in the SUMMIT Study lung cancer screening cohort using symptoms and spirometry
Sophie Tisi, Jennifer L. Dickson, Carolyn Horst, Samantha L. Quaife, Helen Hall, Priyam Verghese, Kylie Gyertson, Vicky Bowyer, Claire Levermore, Anne-Marie Mullin, Jonathan Teague, Laura Farrelly, Arjun Nair, Anand Devaraj, Allan Hackshaw, John R. Hurst, Sam M. Janes
Eur Respir J, 60 (6) 2200795; 10.1183/13993003.00795-2022 | |
Adverse roles of mast cell chymase-1 in COPD
Gang Liu, Andrew G. Jarnicki, Keshav R. Paudel, Wenying Lu, Ridhima Wadhwa, Ashleigh M. Philp, Hannelore Van Eeckhoutte, Jacqueline E. Marshall, Vamshikrishna Malyla, Angelica Katsifis, Michael Fricker, Nicole G. Hansbro, Kamal Dua, Nazanin Z. Kermani, Mathew S. Eapen, Angelica Tiotiu, K. Fan Chung, Gaetano Caramori, Ken Bracke, Ian M. Adcock, Sukhwinder S. Sohal, Peter A. Wark, Brian G. Oliver, Philip M. Hansbro
Eur Respir J, 60 (6) 2101431; 10.1183/13993003.01431-2021 | |
An emerging phenotype of pulmonary arterial hypertension patients carrying SOX17 variants
David Montani, Benoit Lechartier, Barbara Girerd, Mélanie Eyries, Maria-Rosa Ghigna, Laurent Savale, Xavier Jaïs, Andrei Seferian, Mitja Jevnikar, Athénais Boucly, Marianne Riou, Julie Traclet, Ari Chaouat, Maryline Levy, Jerome Le Pavec, Elie Fadel, Frédéric Perros, Florent Soubrier, Martine Remy-Jardin, Olivier Sitbon, Damien Bonnet, Marc Humbert
Eur Respir J, 60 (6) 2200656; 10.1183/13993003.00656-2022 | |
Inhaled seralutinib exhibits potent efficacy in models of pulmonary arterial hypertension
Anna Galkin, Ravikumar Sitapara, Bryan Clemons, Eduardo Garcia, Michael Kennedy, David Guimond, Laura L. Carter, Ashley Douthitt, Robin Osterhout, Aneta Gandjeva, Deborah Slee, Luisa Salter-Cid, Rubin M. Tuder, Lawrence S. Zisman
Eur Respir J, 60 (6) 2102356; 10.1183/13993003.02356-2021 | |
A biomarker assay to risk-stratify patients with symptoms of respiratory tract infection
Shahid Husain, Andrew T. Sage, Lorenzo del Sorbo, Marcelo Cypel, Tereza Martinu, Stephen C. Juvet, Andrea Mariscal, Julie Wright, Bonnie T. Chao, Alaa A. Shamandy, S. Hossein Mousavi, Jin Ma, Bo Wang, Jerome Valero, Mingyao Liu, Megan Landes, Sharaniyaa Balachandran, Kimberley Hudson, Michelle Ngai, Marialessia Capuano, Maria Gelardi, Enrico Lupia, Daniel R. Marinowic, Frederico O. Friedrich, Carine R.R. Schmitz, Leticya S.M. dos Santos, Florencia M. Barbe-Tuana, Marcus H. Jones, Kevin C. Kain, Tony Mazzulli, Sam Sabbah, Shaf Keshavjee
Eur Respir J, 60 (6) 2200459; 10.1183/13993003.00459-2022 | |
Immunomodulation and endothelial barrier protection mediate the association between oral imatinib and mortality in hospitalised COVID-19 patients
Justin de Brabander, Erik Duijvelaar, Job R. Schippers, Patrick J. Smeele, Hessel Peters-Sengers, Jan Willem Duitman, Jurjan Aman, Harm Jan Bogaard, Tom van der Poll, Lieuwe D.J. Bos
Eur Respir J, 60 (6) 2200780; 10.1183/13993003.00780-2022 | |
Human lungs show limited permissiveness for SARS-CoV-2 due to scarce ACE2 levels but virus-induced expansion of inflammatory macrophages
Katja Hönzke, Benedikt Obermayer, Christin Mache, Diana Fathykova, Mirjana Kessler, Simon Dökel, Emanuel Wyler, Morris Baumgardt, Anna Löwa, Karen Hoffmann, Patrick Graff, Jessica Schulze, Maren Mieth, Katharina Hellwig, Zeynep Demir, Barbara Biere, Linda Brunotte, Angeles Mecate-Zambrano, Judith Bushe, Melanie Dohmen, Christian Hinze, Sefer Elezkurtaj, Mario Tönnies, Torsten T. Bauer, Stephan Eggeling, Hong-Linh Tran, Paul Schneider, Jens Neudecker, Jens C. Rückert, Kai M. Schmidt-Ott, Jonas Busch, Frederick Klauschen, David Horst, Helena Radbruch, Josefine Radke, Frank Heppner, Victor M. Corman, Daniela Niemeyer, Marcel A. Müller, Christine Goffinet, Ronja Mothes, Anna Pascual-Reguant, Anja Erika Hauser, Dieter Beule, Markus Landthaler, Stephan Ludwig, Norbert Suttorp, Martin Witzenrath, Achim D. Gruber, Christian Drosten, Leif-Erik Sander, Thorsten Wolff, Stefan Hippenstiel, Andreas C. Hocke
Eur Respir J, 60 (6) 2102725; 10.1183/13993003.02725-2021 | |
Reference equations for evaluation of spirometry function tests in South Asia, and among South Asians living in other countries
Wei Yee Leong, Ananya Gupta, Mehedi Hasan, Sara Mahmood, Samreen Siddiqui, Sajjad Ahmed, Ian Y. Goon, Marie Loh, Theresia H. Mina, Benjamin Lam, Yik Weng Yew, Joanne Ngeow, Jimmy Lee, Eng Sing Lee, Elio Riboli, Paul Elliott, Geak Poh Tan, Sanjay H. Chotirmall, Ananda R. Wickremasinghe, Jaspal S. Kooner, Khadija I. Khawaja, Prasad Katulanda, Malay K. Mridha, Sujeet Jha, Anjana Ranjit Mohan, Guha Pradeepa, Anuradhani Kasturiratne, John C. Chambers
Eur Respir J, 60 (6) 2102962; 10.1183/13993003.02962-2021 | |
Benefits of specialist severe asthma management: demographic and geographic disparities
Charlene Redmond, Liam G. Heaney, Rekha Chaudhuri, David J. Jackson, Andrew Menzies-Gow, Paul Pfeffer, John Busby
Eur Respir J, 60 (6) 2200660; 10.1183/13993003.00660-2022 | |
An observational study to determine the relationship between cough frequency and markers of inflammation in severe asthma
Joshua Holmes, Lorcan P.A. McGarvey, Surinder S. Birring, Hannah Fletcher, Liam G. Heaney
Eur Respir J, 60 (6) 2103205; 10.1183/13993003.03205-2021 | |
Airway autoantibodies are determinants of asthma severity
Brittany Salter, Nan Zhao, Kiho Son, Nadia Suray Tan, Anna Dvorkin-Gheva, Katherine Radford, Nicola LaVigne, Chynna Huang, Melanie Kjarsgaard, Quan-Zhen Li, Konstantinos Tselios, Hui Fang Lim, Nader Khalidi, Parameswaran Nair, Manali Mukherjee
Eur Respir J, 60 (6) 2200442; 10.1183/13993003.00442-2022 | |
Inspiratory hyperoxia suppresses lung cancer metastasis through a MYC/SLC1A5-dependent metabolic pathway
Xiucheng Liu, Hao Qin, Zheng Li, Yin Lv, Shoujie Feng, Wei Zhuang, Xiaoyu Quan, Chen Guo, Chang Chen, Hao Zhang
Eur Respir J, 60 (6) 2200062; 10.1183/13993003.00062-2022 | |
Increasing physical activity in severe asthma: a systematic review and meta-analysis
Rebecca F. McLoughlin, Vanessa L. Clark, Paola D. Urroz, Peter G. Gibson, Vanessa M. McDonald
Eur Respir J, 60 (6) 2200546; 10.1183/13993003.00546-2022 | |
The role of circular RNAs in pulmonary hypertension
Md Khadem Ali, Katharina Schimmel, Lan Zhao, Chun-Kan Chen, Kamal Dua, Mark R. Nicolls, Edda Spiekerkoetter
Eur Respir J, 60 (6) 2200012; 10.1183/13993003.00012-2022 | |
Towards an artificial human lung: modelling organ-like complexity to aid mechanistic understanding
Maria Victoria Humbert, Cosma Mirella Spalluto, Joseph Bell, Cornelia Blume, Franco Conforti, Elizabeth R. Davies, Lareb S.N. Dean, Paul Elkington, Hans Michael Haitchi, Claire Jackson, Mark G. Jones, Matthew Loxham, Jane S. Lucas, Hywel Morgan, Marta Polak, Karl J. Staples, Emily J. Swindle, Liku Tezera, Alastair Watson, Tom M.A. Wilkinson
Eur Respir J, 60 (6) 2200455; 10.1183/13993003.00455-2022 | |
Rectal organoid-guided CFTR modulator therapy restores lung function in a cystic fibrosis patient with the rare 1677delTA/R334W genotype
Georgia Mitropoulou, Nathalie Brandenberg, Sylke Hoehnel, Camilla Ceroni, Zisis Balmpouzis, Sylvain Blanchon, Gian Dorta, Alain Sauty, Angela Koutsokera
Eur Respir J, 60 (6) 2201341; 10.1183/13993003.01341-2022 | |
The effect of regular, low-dose, sustained-release morphine on routine physical activity in people with persistent breathlessness: a hypothesis-generating study
Diana H. Ferreira, Miriam J. Johnson, Daisy J.A. Janssen, Magnus Ekström, David C. Currow
Eur Respir J, 60 (6) 2201484; 10.1183/13993003.01484-2022 | |
Combining digital adherence technology and therapeutic drug monitoring for personalised tuberculosis care
Samiksha Ghimire, Deni Iskandar, Roelina van der Borg-Boekhout, Marina Zenina, Mathieu S. Bolhuis, Huib A.M. Kerstjens, Marieke van Rossum, Daan J. Touw, Tanja R. Zijp, Job F.M. van Boven, Onno W. Akkerman
Eur Respir J, 60 (6) 2201690; 10.1183/13993003.01690-2022 | |
Evaluation of the Global Lung Function Initiative 2012 reference values for spirometry in China: a national cross-sectional study
Feilong Wang, Kun Wang, Cole Bowerman, Hogne Ulla, Jiaxing Sun, Marko Topalovic, Sanja Stanojevic, Qiang Li
Eur Respir J, 60 (6) 2200490; 10.1183/13993003.00490-2022 | |
The aminoglycoside-modifying enzyme Eis2 represents a new potential in vivo target for reducing antimicrobial drug resistance in Mycobacterium abscessus complex
Nicola Ivan Lorè, Fabio Saliu, Andrea Spitaleri, Daniel Schäfle, Francesca Nicola, Daniela Maria Cirillo, Peter Sander
Eur Respir J, 60 (6) 2201541; 10.1183/13993003.01541-2022 | |
Ventilation and tumour spread: still a pending matter
Liu Zhang, Fang Ying Lu, Shao Guang Huang, Qing Yun Li
Eur Respir J, 60 (6) 2201674; 10.1183/13993003.01674-2022 | |
Reply to: Ventilation and tumour spread: still a pending matter
Inés López-Alonso, Antonio Fueyo, Guillermo M. Albaiceta
Eur Respir J, 60 (6) 2201826; 10.1183/13993003.01826-2022 | |
Broadening concepts of core pathobiology in various aspects of COPD development
Eugene H. Walters, Shakti Shukla, Chis Ward
Eur Respir J, 60 (6) 2201531; 10.1183/13993003.01531-2022 | |
Reply to: Broadening concepts of core pathobiology in various aspects of COPD development
Feng Xu, Dragos Vasilescu, Wan Tan, Jim Hogg, Tillie-Louise Hackett
Eur Respir J, 60 (6) 2201796; 10.1183/13993003.01796-2022 | |
U-BIOPRED/BIOAIR proteins: inflammation or infection?
David L. Hahn, Wilmore Webley
Eur Respir J, 60 (6) 2200571; 10.1183/13993003.00571-2022 | |
Reply: U-BIOPRED/BIOAIR proteins: inflammation or infection?
Maria Sparreman Mikus, Johan Kolmert, Lars I. Andersson, Sven-Erik Dahlén, Anna James
Eur Respir J, 60 (6) 2201795; 10.1183/13993003.01795-2022 | |
Pleuroparenchymal fibroelastosis: so many unmet needs
Philippe Bonniaud, Vincent Cottin, Guillaume Beltramo
Eur Respir J, 60 (6) 2201798; 10.1183/13993003.01798-2022 | |
Oh NO! Loss of PHD2 leads to “radical” changes in the lung vasculature
Mark L. Ormiston, Robert P. Jankov, Duncan J. Stewart
Eur Respir J, 60 (6) 2201776; 10.1183/13993003.01776-2022 | |
Utility of whole genome sequencing in assessing risk and clinically relevant outcomes for pulmonary fibrosis
David Zhang, Chad A. Newton, Binhan Wang, Gundula Povysil, Imre Noth, Fernando J. Martinez, Ganesh Raghu, David Goldstein, Christine Kim Garcia
Eur Respir J, 60 (6) 2200577; 10.1183/13993003.00577-2022 | |
Idiopathic pleuroparenchymal fibroelastosis: three-dimensional computed tomography assessment of upper-lobe lung volume
Atsuki Fukada, Yuzo Suzuki, Kazutaka Mori, Masato Kono, Hirotsugu Hasegawa, Dai Hashimoto, Koshi Yokomura, Shiro Imokawa, Yuko Tanaka, Yusuke Inoue, Hironao Hozumi, Masato Karayama, Kazuki Furuhashi, Noriyuki Enomoto, Tomoyuki Fujisawa, Yutaro Nakamura, Naoki Inui, Yoshihisa Fujino, Hidenori Nakamura, Takafumi Suda
Eur Respir J, 60 (6) 2200637; 10.1183/13993003.00637-2022 | |
Endothelial PHD2 deficiency induces nitrative stress via suppression of caveolin-1 in pulmonary hypertension
Bin Liu, Yi Peng, Dan Yi, Narsa Machireddy, Daoyin Dong, Karina Ramirez, Jingbo Dai, Rebecca Vanderpool, Maggie M. Zhu, Zhiyu Dai, You-Yang Zhao
Eur Respir J, 60 (6) 2102643; 10.1183/13993003.02643-2021 | |
Adrenal function recovery after durable oral corticosteroid sparing with benralizumab in the PONENTE study
Andrew Menzies-Gow, Mark Gurnell, Liam G. Heaney, Jonathan Corren, Elisabeth H. Bel, Jorge Maspero, Timothy Harrison, David J. Jackson, David Price, Njira Lugogo, James Kreindler, Annie Burden, Alex de Giorgio-Miller, Sarai Faison, Kelly Padilla, Ubaldo J. Martin, Esther Garcia Gil
Eur Respir J, 60 (6) 2103226; 10.1183/13993003.03226-2021 | |
Green and blue spaces and lung function in the Generation XXI cohort: a life-course approach
Diogo Queiroz Almeida, Inês Paciência, Carla Moreira, João Cavaleiro Rufo, André Moreira, Ana Cristina Santos, Henrique Barros, Ana Isabel Ribeiro
Eur Respir J, 60 (6) 2103024; 10.1183/13993003.03024-2021 | |
Ciliogenesis is intrinsically altered in COPD small airways
Emilie Luczka-Majérus, Arnaud Bonnomet, Adeline Germain, Nathalie Lalun, Claire Kileztky, Jeanne-Marie Perotin, Gaëtan Deslée, Gonzague Delepine, Myriam Polette, Valérian Dormoy, Christelle Coraux
Eur Respir J, 60 (6) 2200791; 10.1183/13993003.00791-2022 | |
Smoking quantitatively increases risk for COVID-19
Fuquan Zhang, Ancha Baranova
Eur Respir J, 60 (6) 2101273; 10.1183/13993003.01273-2021 | |