European Respiratory Journal

The ERJ publishes clinical and experimental work relating to all aspects of adult and paediatric respiratory medicine, including cell biology, epidemiology, immunology, oncology, pathophysiology, imaging, occupational medicine, intensive care, sleep medicine and thoracic surgery. In addition to original research material, the ERJ also publishes editorial commentaries, reviews, short research letters and correspondence to the editor. Articles are published continuously and collected into 12 monthly issues in two volumes per year.

March

Air pollution susceptibility in children with asthma and obesity: tidal volume as key player?
Judith M. Vonk, Jolt Roukema
Eur Respir J, 59 (3) 2102505; 10.1183/13993003.02505-2021
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Adaptive immune responses and protein homeostasis in COPD: the immunoproteasome
Francesca Polverino
Eur Respir J, 59 (3) 2102557; 10.1183/13993003.02557-2021
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Association of lung clearance index with survival in individuals with cystic fibrosis
Johanna Manuela Kurz, Kathryn Angela Ramsey, Romy Rodriguez, Ben Spycher, Reta Fischer Biner, Philipp Latzin, Florian Singer
Eur Respir J, 59 (3) 2100432; 10.1183/13993003.00432-2021
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Artificial intelligence in computed tomography for quantifying lung changes in the era of CFTR modulators
Gael Dournes, Chase S. Hall, Matthew M. Willmering, Alan S. Brody, Julie Macey, Stephanie Bui, Baudouin Denis de Senneville, Patrick Berger, François Laurent, Ilyes Benlala, Jason C. Woods
Eur Respir J, 59 (3) 2100844; 10.1183/13993003.00844-2021
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Novel mechanisms of action contributing to benralizumab's potent anti-eosinophilic activity
Rania Dagher, Varsha Kumar, Alan M. Copenhaver, Sandra Gallagher, Mahboobe Ghaedi, Jonathan Boyd, Paul Newbold, Alison A. Humbles, Roland Kolbeck
Eur Respir J, 59 (3) 2004306; 10.1183/13993003.04306-2020
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Congress or journal article abstractFull text journal articlePDF journal article, handout or slides
Obesity, tidal volume, and pulmonary deposition of fine particulate matter in children with asthma
Nima Afshar-Mohajer, Tianshi David Wu, Rebecca Shade, Emily Brigham, Han Woo, Megan Wood, Rachelle Koehl, Kirsten Koehler, Jason Kirkness, Nadia N. Hansel, Gurumurthy Ramchandran, Meredith C. McCormack
Eur Respir J, 59 (3) 2100209; 10.1183/13993003.00209-2021
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In-hospital and midterm post-discharge complications of adults hospitalised with respiratory syncytial virus infection in France, 2017–2019: an observational study
Alexandre Descamps, Nezha Lenzi, Florence Galtier, Fabrice Lainé, Zineb Lesieur, Philippe Vanhems, Sélilah Amour, Anne-Sophie L'Honneur, Nadhira Fidouh, Vincent Foulongne, Gisèle Lagathu, Xavier Duval, Corinne Merle, Bruno Lina, Fabrice Carrat, Odile Launay, Paul Loubet
Eur Respir J, 59 (3) 2100651; 10.1183/13993003.00651-2021
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Activation of immune cell proteasomes in peripheral blood of smokers and COPD patients: implications for therapy
Ilona E. Kammerl, Sophie Hardy, Claudia Flexeder, Andrea Urmann, Julia Peierl, Yuqin Wang, Oliver Vosyka, Marion Frankenberger, Katrin Milger, Jürgen Behr, Andrea Koch, Juliane Merl-Pham, Stefanie M. Hauck, Charles Pilette, Holger Schulz, Silke Meiners
Eur Respir J, 59 (3) 2101798; 10.1183/13993003.01798-2021
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Gender and racial equity in clinical research for idiopathic pulmonary fibrosis: a systematic review and meta-analysis
Annie-Claude Jalbert, Lyna Siafa, Agnihotram V. Ramanakumar, Deborah Assayag
Eur Respir J, 59 (3) 2102969; 10.1183/13993003.02969-2021
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Lung function during and after acute respiratory infection in COVID-19 positive and negative outpatients
Pekka Tamminen, Dominik Kerimov, Hanna Viskari, Janne Aittoniemi, Jaana Syrjänen, Lauri Lehtimäki
Eur Respir J, 59 (3) 2102837; 10.1183/13993003.02837-2021
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Technical standards for respiratory oscillometry and bronchodilator response cut-offs
Cindy Thamrin, Paul D. Robinson, Claude S. Farah, Gregory G. King
Eur Respir J, 59 (3) 2102663; 10.1183/13993003.02663-2021
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Commemorating World Tuberculosis Day 2022: recent ERJ articles of critical relevance to ending TB and saving lives
Giovanni Battista Migliori, Dennis Falzon, Guy B. Marks, Delia Goletti, Tereza Kasaeva, Susanna Esposito, Marc Humbert
Eur Respir J, 59 (3) 2200149; 10.1183/13993003.00149-2022
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Systematic reviews and meta-analyses in animal model research: as necessary, and with similar pros and cons, as in patient research
Ramon Farré, Miguel A. Martínez-García, David Gozal
Eur Respir J, 59 (3) 2102438; 10.1183/13993003.02438-2021
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Tuberculosis and COVID-19 co-infection: description of the global cohort

Eur Respir J, 59 (3) 2102538; 10.1183/13993003.02538-2021
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Emergence of bedaquiline resistance in a high tuberculosis burden country
Elena Chesov, Dumitru Chesov, Florian P. Maurer, Sönke Andres, Christian Utpatel, Ivan Barilar, Ana Donica, Maja Reimann, Stefan Niemann, Christoph Lange, Valeriu Crudu, Jan Heyckendorf, Matthias Merker
Eur Respir J, 59 (3) 2100621; 10.1183/13993003.00621-2021
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Drug exposure and susceptibility of second-line drugs correlate with treatment response in patients with multidrug-resistant tuberculosis: a multicentre prospective cohort study in China
Xubin Zheng, Lina Davies Forsman, Ziwei Bao, Yan Xie, Zhu Ning, Thomas Schön, Judith Bruchfeld, Biao Xu, Jan-Willem Alffenaar, Yi Hu
Eur Respir J, 59 (3) 2101925; 10.1183/13993003.01925-2021
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Biomarker signatures for progressive idiopathic pulmonary fibrosis
Britt Clynick, Tamera J. Corte, Helen E. Jo, Iain Stewart, Ian N. Glaspole, Christopher Grainge, Toby M. Maher, Vidya Navaratnam, Richard Hubbard, Peter M.A. Hopkins, Paul N. Reynolds, Sally Chapman, Christopher Zappala, Gregory J. Keir, Wendy A. Cooper, Annabelle M. Mahar, Samantha Ellis, Nicole S. Goh, Emma De Jong, Lilian Cha, Dino B.A. Tan, Lucy Leigh, Christopher Oldmeadow, E. Haydn Walters, R. Gisli Jenkins, Yuben Moodley
Eur Respir J, 59 (3) 2101181; 10.1183/13993003.01181-2021
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Nintedanib in progressive interstitial lung diseases: data from the whole INBUILD trial
Kevin R. Flaherty, Athol U. Wells, Vincent Cottin, Anand Devaraj, Yoshikazu Inoue, Luca Richeldi, Simon L.F. Walsh, Martin Kolb, Dirk Koschel, Teng Moua, Susanne Stowasser, Rainer-Georg Goeldner, Rozsa Schlenker-Herceg, Kevin K. Brown
Eur Respir J, 59 (3) 2004538; 10.1183/13993003.04538-2020
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Helmet noninvasive ventilation compared to facemask noninvasive ventilation and high-flow nasal cannula in acute respiratory failure: a systematic review and meta-analysis
Dipayan Chaudhuri, Rehman Jinah, Karen E.A. Burns, Federico Angriman, Bruno L. Ferreyro, Laveena Munshi, Ewan Goligher, Damon Scales, Deborah J. Cook, Tommaso Mauri, Bram Rochwerg
Eur Respir J, 59 (3) 2101269; 10.1183/13993003.01269-2021
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Mendelian randomisation and experimental medicine approaches to interleukin-6 as a drug target in pulmonary arterial hypertension
Mark Toshner, Colin Church, Lars Harbaum, Christopher Rhodes, Sofia S. Villar Moreschi, James Liley, Rowena Jones, Amit Arora, Ken Batai, Ankit A. Desai, John G. Coghlan, J. Simon R. Gibbs, Dee Gor, Stefan Gräf, Louise Harlow, Jules Hernandez-Sanchez, Luke S. Howard, Marc Humbert, Jason Karnes, David G. Kiely, Rick Kittles, Emily Knightbridge, Brian Lam, Katie A. Lutz, William C. Nichols, Michael W. Pauciulo, Joanna Pepke-Zaba, Jay Suntharalingam, Florent Soubrier, Richard C. Trembath, Tae-Hwi L. Schwantes-An, S. John Wort, Martin R. Wilkins, Sean Gaine, Nicholas W. Morrell, Paul A. Corris
Eur Respir J, 59 (3) 2002463; 10.1183/13993003.02463-2020
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Relationship between glucosamine use and the risk of lung cancer: data from a nationwide prospective cohort study
Guowei Li, Xuhui Zhang, Yingxin Liu, Junguo Zhang, Likang Li, Xin Huang, Lehana Thabane, Gregory Y.H. Lip
Eur Respir J, 59 (3) 2101399; 10.1183/13993003.01399-2021
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Identification of asthma-associated microRNAs in bronchial biopsies
Mirjam P. Roffel, Ilse M. Boudewijn, Jos L.L. van Nijnatten, Alen Faiz, Corneel J. Vermeulen, Antoon J. van Oosterhout, Karen Affleck, Wim Timens, Ken R. Bracke, Tania Maes, Irene H. Heijink, Corry-Anke Brandsma, Maarten van den Berge
Eur Respir J, 59 (3) 2101294; 10.1183/13993003.01294-2021
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Congress or journal article abstractFull text journal articlePDF journal article, handout or slides
Anti-IL5 mepolizumab minimally influences residual blood eosinophils in severe asthma
Glenn Van Hulst, Joseph Jorssen, Nathalie Jacobs, Monique Henket, Renaud Louis, Florence Schleich, Fabrice Bureau, Christophe J. Desmet
Eur Respir J, 59 (3) 2100935; 10.1183/13993003.00935-2021
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Congress or journal article abstractFull text journal articlePDF journal article, handout or slides
Asthma and COVID-19 risk: a systematic review and meta-analysis
Anthony P. Sunjaya, Sabine M. Allida, Gian Luca Di Tanna, Christine R. Jenkins
Eur Respir J, 59 (3) 2101209; 10.1183/13993003.01209-2021
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Congress or journal article abstractFull text journal articlePDF journal article, handout or slides
Lifting dyspnoea invisibility: COVID-19 face masks, the experience of breathing discomfort, and improved lung health perception – a French nationwide survey
Laure Serresse, Noémie Simon-Tillaux, Maxens Decavèle, Frederick Gay, Nathalie Nion, Sophie Lavault, Antoine Guerder, Antoine Châtelet, Frédéric Dabi, Alexandre Demoule, Capucine Morélot-Panzini, Caroline Moricot, Thomas Similowski
Eur Respir J, 59 (3) 2101459; 10.1183/13993003.01459-2021
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Blood leukocyte transcriptomes in Gram-positive and Gram-negative community-acquired pneumonia
Liza Pereverzeva, Fabrice Uhel, Hessel Peters Sengers, Joe Butler, Lonneke A. van Vught, Katie L. Burnham, Emma E. Davenport, Julian C. Knight, Olaf L. Cremer, Marcus J. Schultz, Marc M.J. Bonten, Brendon P. Scicluna, Tom van der Poll
Eur Respir J, 59 (3) 2101856; 10.1183/13993003.01856-2021
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Lrig1 expression identifies airway basal cells with high proliferative capacity and restricts lung squamous cell carcinoma growth
Laura Succony, Sandra Gómez-López, Adam Pennycuick, Ahmed S.N. Alhendi, Derek Davies, Sarah E. Clarke, Kate H.C. Gowers, Nicholas A. Wright, Kim B. Jensen, Sam M. Janes
Eur Respir J, 59 (3) 2000816; 10.1183/13993003.00816-2020
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Intermittent hypoxia-related alterations in vascular structure and function: a systematic review and meta-analysis of rodent data
Olfa Harki, Quentin Boete, Jean-Louis Pépin, Claire Arnaud, Elise Belaidi, Gilles Faury, Charles Khouri, Anne Briançon-Marjollet
Eur Respir J, 59 (3) 2100866; 10.1183/13993003.00866-2021
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Bedaquiline can act as core drug in a standardised treatment regimen for fluoroquinolone-resistant rifampicin-resistant tuberculosis
Tom Decroo, Kya Jai Maug Aung, Mohamed Anwar Hossain, Mourad Gumusboga, Nimer Ortuno-Gutierrez, Bouke Catherine De Jong, Armand Van Deun
Eur Respir J, 59 (3) 2102124; 10.1183/13993003.02124-2021
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Congress or journal article abstractFull text journal articlePDF journal article, handout or slides
Tailored approaches facilitate high completion of tuberculosis infection treatment among migrants
Ineke Spruijt, Chantal Joren, Susan van den Hof, Connie Erkens
Eur Respir J, 59 (3) 2102077; 10.1183/13993003.02077-2021
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Congress or journal article abstractFull text journal articlePDF journal article, handout or slides
QIAreach QuantiFERON-TB for the diagnosis of Mycobacterium tuberculosis infection
Francesca Saluzzo, Paola Mantegani, Valeria Poletti de Chaurand, Daniela Maria Cirillo
Eur Respir J, 59 (3) 2102563; 10.1183/13993003.02563-2021
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Congress or journal article abstractFull text journal articlePDF journal article, handout or slides
In vivo microevolution of Mycobacterium tuberculosis and transient emergence of atpE_Ala63Pro mutation during treatment in a pre-XDR TB patient
Arash Ghodousi, Alamdar Hussain Rizvi, Faisal Masood Khanzada, Nasim Akhtar, Abdul Ghafoor, Alberto Trovato, Daniela Maria Cirillo, Sabira Tahseen
Eur Respir J, 59 (3) 2102102; 10.1183/13993003.02102-2021
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Congress or journal article abstractFull text journal articlePDF journal article, handout or slides
Cycloserine did not increase depression incidence or severity at standard dosing for multidrug-resistant tuberculosis
Jeffrey A. Tornheim, Zarir F. Udwadia, Prerna R. Arora, Ishita Gajjar, Nikhil Gupte, Samridhi Sharma, Megha Karane, Namrata Sawant, Nisha Kharat, Alexander J. Blum, Shri Vijay Bala Yogendra Shivakumar, Jai B. Mullerpattan, Lancelot M. Pinto, Tester F. Ashavaid, Amita Gupta, Camilla Rodrigues
Eur Respir J, 59 (3) 2102511; 10.1183/13993003.02511-2021
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Congress or journal article abstractFull text journal articlePDF journal article, handout or slides
Global reporting on tuberculosis preventive treatment among contacts
Dennis Falzon, Saskia den Boon, Avinash Kanchar, Matteo Zignol, Giovanni Battista Migliori, Tereza Kasaeva
Eur Respir J, 59 (3) 2102753; 10.1183/13993003.02753-2021
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Congress or journal article abstractFull text journal articlePDF journal article, handout or slides
Acute exacerbation of idiopathic pulmonary fibrosis after SARS-CoV-2 vaccination
Tomohiro Bando, Reoto Takei, Yoshikazu Mutoh, Hajime Sasano, Yasuhiko Yamano, Toshiki Yokoyama, Toshiaki Matsuda, Kensuke Kataoka, Tomoki Kimura, Yasuhiro Kondoh
Eur Respir J, 59 (3) 2102806; 10.1183/13993003.02806-2021
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Add-on inhaled budesonide in the treatment of hospitalised patients with COVID-19: a randomised clinical trial
Alvar Agustí, Gaston De Stefano, Alberto Levi, Xavier Muñoz, Christian Romero-Mesones, Oriol Sibila, Alejandra Lopez-Giraldo, Vicente Plaza Moral, Elena Curto, Andrés L. Echazarreta, Silvana E. Márquez, Sergi Pascual-Guàrdia, Salud Santos, Alicia Marin, Luis Valdés, Fernando Saldarini, Clara Salgado, Georgina Casanovas, Sara Varea, José Ríos, Rosa Faner
Eur Respir J, 59 (3) 2103036; 10.1183/13993003.03036-2021
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Congress or journal article abstractFull text journal articlePDF journal article, handout or slides
Methodological caveats regarding “Novel insights into surfactant protein C trafficking revealed through the study of a pathogenic mutant”
Surafel Mulugeta, Timothy E. Weaver, Michael F. Beers
Eur Respir J, 59 (3) 2102974; 10.1183/13993003.02974-2021
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Congress or journal article abstractFull text journal articlePDF journal article, handout or slides
The coexistence of asthma and COPD: some considerations about prevalence and lung function decline
Alessandro Marcon, Francesca Locatelli, Simone Accordini
Eur Respir J, 59 (3) 2200096; 10.1183/13993003.00096-2022
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Congress or journal article abstractFull text journal articlePDF journal article, handout or slides
Measurement of hypoxia in the lung in idiopathic pulmonary fibrosis: a matter of control
Pierre-Simon Bellaye, Guillaume Beltramo, Olivier Burgy, Bertrand Collin, Alexandre Cochet, Philippe Bonniaud
Eur Respir J, 59 (3) 2102711; 10.1183/13993003.02711-2021
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Congress or journal article abstractFull text journal articlePDF journal article, handout or slides
Reply: Measurement of hypoxia in the lung in idiopathic pulmonary fibrosis: a matter of control
Joanna C. Porter, Thida Win, Kjell Erlandsson, Kris Thielemans, Ashley M. Groves
Eur Respir J, 59 (3) 2103124; 10.1183/13993003.03124-2021
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