European Respiratory Journal

The ERJ publishes clinical and experimental work relating to all aspects of adult and paediatric respiratory medicine, including cell biology, epidemiology, immunology, oncology, pathophysiology, imaging, occupational medicine, intensive care, sleep medicine and thoracic surgery. In addition to original research material, the ERJ also publishes editorial commentaries, reviews, short research letters and correspondence to the editor. Articles are published continuously and collected into 12 monthly issues in two volumes per year.

September

Celebrating the ERS HERMES Self-Assessment Course Robert Primhak, Zuzana Tumova, Amy Auer, Daiana Stolz Eur Respir J, 56 (3) 2002895; 10.1183/13993003.02895-2020
ERS Scientific Working Group 09.04, “Psychologists and behavioural scientists”: the next step towards multidisciplinary respiratory care Andreas von Leupoldt, Lisa Jane Brighton, Jeannette Peters, Eleonora Volpato, Marieke Verkleij, Ann Hutchinson, Monique Heijmans, Ingeborg Farver-Vestergaard, Daniel Langer, Martijn A. Spruit Eur Respir J, 56 (3) 2001881; 10.1183/13993003.01881-2020
Pandemic treatments on trial: the bigger picture. N of many thinking in an N of one scenario Tom Kotsimbos, Marc Humbert Eur Respir J, 56 (3) 2002281; 10.1183/13993003.02281-2020
Imaging risk in pulmonary arterial hypertension Roberto Badagliacca, Carmine Dario Vizza Eur Respir J, 56 (3) 2002313; 10.1183/13993003.02313-2020
Carriers of a single CFTR mutation are asymptomatic: an evolving dogma? Clémence Martin, Pierre-Régis Burgel Eur Respir J, 56 (3) 2002645; 10.1183/13993003.02645-2020
Intermittent regimens for tuberculosis treatment: Back to the Future? Jan-Willem C. Alffenaar, Simon Tiberi, Daniela M. Cirillo, Giovanni Battista Migliori Eur Respir J, 56 (3) 2002510; 10.1183/13993003.02510-2020
Sarcoidosis in a time of pandemic Praveen Govender, Yvette C. Cozier Eur Respir J, 56 (3) 2002376; 10.1183/13993003.02376-2020
ECMO support for viral induced cardiogenic shock: a bridge too far? Trevor J. Williams, Vincent Pellegrino Eur Respir J, 56 (3) 2002129; 10.1183/13993003.02129-2020
Oscillometry: old physiology with a bright future Peter M.A. Calverley, Ramon Farré Eur Respir J, 56 (3) 2001815; 10.1183/13993003.01815-2020
COVID-19: guidance on palliative care from a European Respiratory Society international task force Daisy J.A. Janssen, Magnus Ekström, David C. Currow, Miriam J. Johnson, Matthew Maddocks, Anita K. Simonds, Thomy Tonia, Kristoffer Marsaa Eur Respir J, 56 (3) 2002583; 10.1183/13993003.02583-2020
A comprehensive echocardiographic method for risk stratification in pulmonary arterial hypertension Stefano Ghio, Valentina Mercurio, Federico Fortuni, Paul R. Forfia, Henning Gall, Ardeschir Ghofrani, Stephen C. Mathai, Jeremy A. Mazurek, Monica Mukherjee, Manuel Richter, Laura Scelsi, Paul M. Hassoun, Khodr Tello Eur Respir J, 56 (3) 2000513; 10.1183/13993003.00513-2020
Normal spirometry predictive values for the Western Indian adult population Dhiraj Agarwal, Richard A. Parker, Hilary Pinnock, Sudipto Roy, Deesha Ghorpade, Sundeep Salvi, Parag Khatavkar, Sanjay Juvekar Eur Respir J, 56 (3) 1902129; 10.1183/13993003.02129-2019
Morbidity and mortality in carriers of the cystic fibrosis mutation CFTR Phe508del in the general population Yunus Çolak, Børge G. Nordestgaard, Shoaib Afzal Eur Respir J, 56 (3) 2000558; 10.1183/13993003.00558-2020
Gene expression and in situ protein profiling of candidate SARS-CoV-2 receptors in human airway epithelial cells and lung tissue Jennifer A. Aguiar, Benjamin J-M. Tremblay, Michael J. Mansfield, Owen Woody, Briallen Lobb, Arinjay Banerjee, Abiram Chandiramohan, Nicholas Tiessen, Quynh Cao, Anna Dvorkin-Gheva, Spencer Revill, Matthew S. Miller, Christopher Carlsten, Louise Organ, Chitra Joseph, Alison John, Paul Hanson, Richard C. Austin, Bruce M. McManus, Gisli Jenkins, Karen Mossman, Kjetil Ask, Andrew C. Doxey, Jeremy A. Hirota Eur Respir J, 56 (3) 2001123; 10.1183/13993003.01123-2020
The risk of multidrug- or rifampicin-resistance in males versus females with tuberculosis C. Finn McQuaid, Katherine C. Horton, Anna S. Dean, Gwenan M. Knight, Richard G. White Eur Respir J, 56 (3) 2000626; 10.1183/13993003.00626-2020
Fully weekly antituberculosis regimen: a proof-of-concept study Fatma Kort, Laure Fournier Le Ray, Aurélie Chauffour, Vincent Jarlier, Nacer Lounis, Koen Andries, Alexandra Aubry, Lorenzo Guglielmetti, Nicolas Veziris Eur Respir J, 56 (3) 1902502; 10.1183/13993003.02502-2019
Risk of first and recurrent serious infection in sarcoidosis: a Swedish register-based cohort study Marios Rossides, Susanna Kullberg, Anders Eklund, Daniela Di Giuseppe, Johan Grunewald, Johan Askling, Elizabeth V. Arkema Eur Respir J, 56 (3) 2000767; 10.1183/13993003.00767-2020
Mechanical circulatory support in refractory cardiogenic shock due to influenza virus-related myocarditis Jan-Thorben Sieweke, Muharrem Akin, Sebastian Stetskamp, Christian Riehle, Danny Jonigk, Ulrike Flierl, Tobias J. Pfeffer, Valentin Hirsch, Jochen Dutzmann, Marius M. Hoeper, Christian Kühn, Johann Bauersachs, Andreas Schäfer Eur Respir J, 56 (3) 2000925; 10.1183/13993003.00925-2020
Day-to-day variability of forced oscillatory mechanics for early detection of acute exacerbations in COPD Sabine C. Zimmermann, Jacqueline Huvanandana, Chinh D. Nguyen, Amy Bertolin, Joanna C. Watts, Alessandro Gobbi, Claude S. Farah, Matthew J. Peters, Raffaele L. Dellacà, Gregory G. King, Cindy Thamrin Eur Respir J, 56 (3) 1901739; 10.1183/13993003.01739-2019
Autotitrating external positive end-expiratory airway pressure to abolish expiratory flow limitation during tidal breathing in patients with severe COPD: a physiological study Eui-Sik Suh, Pasquale Pompilio, Swapna Mandal, Peter Hill, Georgios Kaltsakas, Patrick B. Murphy, Robert Romano, John Moxham, Raffaele Dellaca, Nicholas Hart Eur Respir J, 56 (3) 1902234; 10.1183/13993003.02234-2019
Effects of downhill walking in pulmonary rehabilitation for patients with COPD: a randomised controlled trial Carlos Augusto Camillo, Christian Robert Osadnik, Chris Burtin, Stephanie Everaerts, Miek Hornikx, Heleen Demeyer, Matthias Loeckx, Fernanda Machado Rodrigues, Karen Maes, Ghislaine Gayan-Ramirez, Wim Janssens, Thierry Troosters Eur Respir J, 56 (3) 2000639; 10.1183/13993003.00639-2020
Cigarette smoke-initiated autoimmunity facilitates sensitisation to elastin-induced COPD-like pathologies in mice Jie-Sen Zhou, Zhou-Yang Li, Xu-Chen Xu, Yun Zhao, Yong Wang, Hai-Pin Chen, Min Zhang, Yin-Fang Wu, Tian-Wen Lai, Chun-Hong Di, Ling-Ling Dong, Juan Liu, Nan-Xia Xuan, Chen Zhu, Yan-Ping Wu, Hua-Qiong Huang, Fu-Gui Yan, Wen Hua, Yi Wang, Wei-Ning Xiong, Hui Qiu, Tao Chen, Dong Weng, Hui-Ping Li, Xiaobo Zhou, Lie Wang, Fang Liu, Xin Lin, Song-Min Ying, Wen Li, Mitsuru Imamura, Mary E. Choi, Martin R. Stampfli, Augustine M.K. Choi, Zhi-Hua Chen, Hua-Hao Shen Eur Respir J, 56 (3) 2000404; 10.1183/13993003.00404-2020
SMART and as-needed therapies in mild-to-severe asthma: a network meta-analysis Paola Rogliani, Beatrice Ludovica Ritondo, Josuel Ora, Mario Cazzola, Luigino Calzetta Eur Respir J, 56 (3) 2000625; 10.1183/13993003.00625-2020
Epigenome-wide association study of DNA methylation and adult asthma in the Agricultural Lung Health Study Thanh T. Hoang, Sinjini Sikdar, Cheng-Jian Xu, Mi Kyeong Lee, Jonathan Cardwell, Erick Forno, Medea Imboden, Ayoung Jeong, Anne-Marie Madore, Cancan Qi, Tianyuan Wang, Brian D. Bennett, James M. Ward, Christine G. Parks, Laura E. Beane-Freeman, Debra King, Alison Motsinger-Reif, David M. Umbach, Annah B. Wyss, David A. Schwartz, Juan C. Celedón, Catherine Laprise, Carole Ober, Nicole Probst-Hensch, Ivana V. Yang, Gerard H. Koppelman, Stephanie J. London Eur Respir J, 56 (3) 2000217; 10.1183/13993003.00217-2020
Innate lymphoid cells in isocyanate-induced asthma: role of microRNA-155 Evy E. Blomme, Sharen Provoost, Erica Bazzan, Hannelore P. Van Eeckhoutte, Mirjam P. Roffel, Lore Pollaris, Annelies Bontinck, Matteo Bonato, Louise Vandenbroucke, Fien Verhamme, Guy F. Joos, Manuel G. Cosio, Jeroen A. J. Vanoirbeek, Guy G. Brusselle, Marina Saetta, Tania Maes Eur Respir J, 56 (3) 1901289; 10.1183/13993003.01289-2019
Late-onset “acute fibrinous and organising pneumonia” impairs long-term lung allograft function and survival Arno Vanstapel, Stijn E. Verleden, Birgit Weynand, Eric Verbeken, Laurens De Sadeleer, Bart M. Vanaudenaerde, Geert M. Verleden, Robin Vos Eur Respir J, 56 (3) 1902292; 10.1183/13993003.02292-2019
Artificial intelligence techniques in asthma: a systematic review and critical appraisal of the existing literature Konstantinos P. Exarchos, Maria Beltsiou, Chainti-Antonella Votti, Konstantinos Kostikas Eur Respir J, 56 (3) 2000521; 10.1183/13993003.00521-2020
Pathogenesis of COVID-19-induced ARDS: implications for an ageing population Manuel A. Torres Acosta, Benjamin D. Singer Eur Respir J, 56 (3) 2002049; 10.1183/13993003.02049-2020
Extrafine triple therapy in patients with asthma and persistent airflow limitation Dave Singh, Johann Christian Virchow, Giorgio Walter Canonica, Andrea Vele, Maxim Kots, George Georges, Alberto Papi Eur Respir J, 56 (3) 2000476; 10.1183/13993003.00476-2020
Effect of history of tuberculosis on specificity of Xpert MTB/RIF Frederick Haraka, Samuel G. Schumacher, Amanda Ross, Anna Mantsoki, Sebastien Gagneux, Klaus Reither, Claudia M. Denkinger Eur Respir J, 56 (3) 2000343; 10.1183/13993003.00343-2020
Effect of long-acting ß-agonist on bronchodilator response in children with asthma Jessica Taytard, Camille Aupiais, Sophie Jovien, Jessica Assouline Kabla, Noémie Haziot, Marilyn Fuger, Corinne Alberti, Nicole Beydon Eur Respir J, 56 (3) 1902010; 10.1183/13993003.02010-2019
Elevated ACE-2 expression in the olfactory neuroepithelium: implications for anosmia and upper respiratory SARS-CoV-2 entry and replication Mengfei Chen, Wenjuan Shen, Nicholas R. Rowan, Heather Kulaga, Alexander Hillel, Murugappan Ramanathan, Andrew P. Lane Eur Respir J, 56 (3) 2001948; 10.1183/13993003.01948-2020
Ventilatory demand–capacity imbalance during incremental exercise in COPD: an in silico perspective J. Alberto Neder Eur Respir J, 56 (3) 2000495; 10.1183/13993003.00495-2020
Iron bioavailability and cardiopulmonary function during ascent to very high altitude David A. Holdsworth, Matthew C. Frise, Josh Bakker-Dyos, Christopher Boos, Keith L. Dorrington, David Woods, Adrian Mellor, Peter A. Robbins Eur Respir J, 56 (3) 1902285; 10.1183/13993003.02285-2019
Socioeconomic correlates of SARS-CoV-2 and influenza H1N1 outbreaks Jan Christian Kaiser, Georgios T. Stathopoulos Eur Respir J, 56 (3) 2001400; 10.1183/13993003.01400-2020
Comparison of severity scores for COVID-19 patients with pneumonia: a retrospective study Guohui Fan, Chao Tu, Fei Zhou, Zhibo Liu, Yeming Wang, Bin Song, Xiaoying Gu, Yimin Wang, Yuan Wei, Hui Li, Xudong Wu, Jiuyang Xu, Shengjin Tu, Yi Zhang, Wenjuan Wu, Bin Cao Eur Respir J, 56 (3) 2002113; 10.1183/13993003.02113-2020
Circulating RNA differences between patients with stable and progressive idiopathic pulmonary fibrosis Britt Clynick, Helen E. Jo, Tamera J. Corte, Ian N. Glaspole, Christopher Grainge, Peter M.A. Hopkins, Paul N. Reynolds, Sally Chapman, E. Haydn Walters, Christopher Zappala, Gregory J. Keir, Wendy A. Cooper, Annabelle M. Mahar, Samantha Ellis, Nicole S. Goh, Svetlana Baltic, Marisa Ryan, Dino B.A. Tan, Yuben P. Moodley Eur Respir J, 56 (3) 1902058; 10.1183/13993003.02058-2019
The impact of different antibiotic treatment regimens on mortality in Mycobacterium avium complex pulmonary disease: a population-based cohort study Sarah K. Brode, Hannah Chung, Michael A. Campitelli, Jeffrey C. Kwong, Rinku Sutradhar, Alex Marchand-Austin, Kevin L. Winthrop, Frances B. Jamieson, Theodore K. Marras Eur Respir J, 56 (3) 1901875; 10.1183/13993003.01875-2019
Evaluation of pulmonary hypertension by right heart catheterisation: does timing matter? Athiththan Yogeswaran, Manuel Jonas Richter, Natascha Sommer, Hossein Ardeschir Ghofrani, Werner Seeger, Henning Gall, Khodr Tello Eur Respir J, 56 (3) 1901892; 10.1183/13993003.01892-2019
Initial combination therapy of macitentan and tadalafil in pulmonary arterial hypertension Olivier Sitbon, Vincent Cottin, Matthieu Canuet, Pierre Clerson, Virginie Gressin, Loïc Perchenet, Laurent Bertoletti, Hélène Bouvaist, François Picard, Grégoire Prévot, Emmanuel Bergot, Gérald Simonneau Eur Respir J, 56 (3) 2000673; 10.1183/13993003.00673-2020
Ozone exposure leads to changes in airway permeability, microbiota and metabolome: a randomised, double-blind, crossover trial Yue Niu, Renjie Chen, Cuiping Wang, Weidong Wang, Jing Jiang, Weidong Wu, Jing Cai, Zhuohui Zhao, Xiaohui Xu, Haidong Kan Eur Respir J, 56 (3) 2000165; 10.1183/13993003.00165-2020
JAK inhibitors in COVID-19: the need for vigilance regarding increased inherent thrombotic risk Puja Mehta, Coziana Ciurtin, Marie Scully, Marcel Levi, Rachel C. Chambers Eur Respir J, 56 (3) 2001919; 10.1183/13993003.01919-2020
Insight into the impact of the COVID-19 epidemic on tuberculosis burden in China Hongguang Chen, Konglai Zhang Eur Respir J, 56 (3) 2002710; 10.1183/13993003.02710-2020
Similarities between COVID-19 and anti-MDA5 syndrome: what can we learn for better care? Margherita Giannini, Mickael Ohana, Benoit Nespola, Giovanni Zanframundo, Bernard Geny, Alain Meyer Eur Respir J, 56 (3) 2001618; 10.1183/13993003.01618-2020
Antibiotics for paediatric community-acquired pneumonia in resource-constrained settings Amy Sarah Ginsburg, Keith P. Klugman Eur Respir J, 56 (3) 2002773; 10.1183/13993003.02773-2020
Characteristics and outcomes of health and social care workers testing positive for SARS-CoV-2 in the Tayside region of Scotland Moneeza K. Siddiqui, Benjamin Parcell, Sarah Allstaff, Colin Palmer, James D. Chalmers, Samira Bell Eur Respir J, 56 (3) 2002568; 10.1183/13993003.02568-2020
SARS-CoV-2 disrupts clinical research: the role of a rare disease-specific trial network Silke van Koningsbruggen-Rietschel, Fiona Dunlevy, Veerle Bulteel, Damian G. Downey, Lieven Dupont Eur Respir J, 56 (3) 2002114; 10.1183/13993003.02114-2020
COVID-19 prediction models should adhere to methodological and reporting standards Gary S. Collins, Maarten van Smeden, Richard D. Riley Eur Respir J, 56 (3) 2002643; 10.1183/13993003.02643-2020
Reply to “COVID-19 prediction models should adhere to methodological and reporting standards” Guangyao Wu, Henry C. Woodruff, Avishek Chatterjee, Philippe Lambin Eur Respir J, 56 (3) 2002918; 10.1183/13993003.02918-2020
Rationale and significance of patient selection in awake prone positioning for COVID-19 pneumonia Ching-Feng Huang, Chee Kiang Tay, Ya-Fang Zhuang, Jiaxuan Liu, Duu Wen Sewa Eur Respir J, 56 (3) 2002173; 10.1183/13993003.02173-2020
Rationale and significance of patient selection in awake prone positioning for COVID-19 pneumonia Ziqin Ng, Woo Chiao Tay, Choon Heng Benjamin Ho Eur Respir J, 56 (3) 2002571; 10.1183/13993003.02571-2020
Systemic effects of fluticasone on blood eosinophils in bronchiectasis Brian Lipworth, Rory Chan, Chris RuiWen Kuo Eur Respir J, 56 (3) 2002005; 10.1183/13993003.02005-2020
Blood eosinophils do not predict inhaled budesonide response in bronchiectasis Stefano Aliberti, Giovanni Sotgiu, Miguel-Angel Martinez Garcia Eur Respir J, 56 (3) 2002210; 10.1183/13993003.02210-2020
Potential of regulatory T-cell-based therapies in the management of severe COVID-19 Emmanuel Stephen-Victor, Mrinmoy Das, Anupama Karnam, Bruno Pitard, Jean-François Gautier, Jagadeesh Bayry Eur Respir J, 56 (3) 2002182; 10.1183/13993003.02182-2020
Predictors of mortality for patients with COVID-19 pneumonia caused by SARS-CoV-2 Hai-Jun Yang, Yan-Mei Zhang, Min Yang, Xing Huang Eur Respir J, 56 (3) 2002439; 10.1183/13993003.02439-2020
Predictors of mortality for patients with COVID-19 pneumonia caused by SARS-CoV-2 Rong-Hui Du, Li-Rong Liang, Cheng-Qing Yang, Wen Wang, Tan-Ze Cao, Ming Li, Guang-Yun Guo, Juan Du, Chun-Lan Zheng, Qi Zhu, Ming Hu, Xu-Yan Li, Peng Peng, Huan-Zhong Shi Eur Respir J, 56 (3) 2002961; 10.1183/13993003.02961-2020
“Predictors of mortality for patients with COVID-19 pneumonia caused by SARS-CoV-2: a prospective cohort study.” Rong-Hui Du, Li-Rong Liang, Cheng-Qing Yang, Wen Wang, Tan-Ze Cao, Ming Li, Guang-Yun Guo, Juan Du, Chun-Lan Zheng, Qi Zhu, Ming Hu, Xu-Yan Li, Peng Peng and Huan-Zhong Shi. Eur Respir J 2020; 55: 2000524. Eur Respir J, 56 (3) 2050524; 10.1183/13993003.50524-2020