European Respiratory Journal

The ERJ publishes clinical and experimental work relating to all aspects of adult and paediatric respiratory medicine, including cell biology, epidemiology, immunology, oncology, pathophysiology, imaging, occupational medicine, intensive care, sleep medicine and thoracic surgery. In addition to original research material, the ERJ also publishes editorial commentaries, reviews, short research letters and correspondence to the editor. Articles are published continuously and collected into 12 monthly issues in two volumes per year.

June

Editorials

COVID-19 and pulmonary rehabilitation: preparing for phase three Massimiliano Polastri, Stefano Nava, Enrico Clini, Michele Vitacca, Rik Gosselink Eur Respir J, 55 (6) 2001822; 10.1183/13993003.01822-2020
An Italian sacrifice to the COVID-19 epidemic Stefano Nava, Roberto Tonelli, Enrico M. Clini Eur Respir J, 55 (6) 2001445; 10.1183/13993003.01445-2020
Putative contributions of circadian clock and sleep in the context of SARS-CoV-2 infection Miguel Meira e Cruz, Masaaki Miyazawa, David Gozal Eur Respir J, 55 (6) 2001023; 10.1183/13993003.01023-2020
Expanding the spectrum of European Respiratory Society official scientific documents: short documents complement clinical practice guidelines, statements and technical standards Nicolas Roche, Thomy Tonia, Marc Miravitlles, Valérie Vaccaro, Céline Genton, Tobias Welte, Thierry Troosters, Guy Brusselle, Chris Brightling Eur Respir J, 55 (6) 2001030; 10.1183/13993003.01030-2020
Progressive fibrosing interstitial lung disease: we know it behaves badly, but what does that mean? Amornpun Wongkarnjana, Christopher J. Ryerson Eur Respir J, 55 (6) 2000894; 10.1183/13993003.00894-2020
Collagen IV: a critical new starting point for engineering upper airways Martina M. De Santis, Darcy E. Wagner Eur Respir J, 55 (6) 2001130; 10.1183/13993003.01130-2020
Subtle signs – red flags Jürgen Behr, Marius M. Hoeper Eur Respir J, 55 (6) 2000606; 10.1183/13993003.00606-2020
Easier access to mechanical ventilation worldwide: an urgent need for low income countries, especially in face of the growing COVID-19 crisis Claude Guérin, Patrick Lévy Eur Respir J, 55 (6) 2001271; 10.1183/13993003.01271-2020
Finding the true prevalence of obstructive lung disease: two steps forward and one step back Richard E.K. Russell, Kay Wang Eur Respir J, 55 (6) 2001514; 10.1183/13993003.01514-2020
*a₁-antitrypsin PISZ genotype: a SERPINA1 deficiency haplotype with uncertain clinical and therapeutic implications** Ignacio Blanco, Isidro Diego Eur Respir J, 55 (6) 2000713; 10.1183/13993003.00713-2020
Idiopathic pulmonary fibrosis: do scientists focus on publishing rather than on clinical relevance? C. Arnold Spek, JanWillem Duitman Eur Respir J, 55 (6) 2000811; 10.1183/13993003.00811-2020

ERS/ESTS/EACTS/ESTRO guidelines

ERS/ESTS/EACTS/ESTRO guidelines for the management of malignant pleural mesothelioma Arnaud Scherpereel, Isabelle Opitz, Thierry Berghmans, Ioannis Psallidas, Markus Glatzer, David Rigau, Philippe Astoul, Servet Bölükbas, Jeanette Boyd, Johan Coolen, Charlotte De Bondt, Dirk De Ruysscher, Valerie Durieux, Corinne Faivre-Finn, Dean Fennell, Francoise Galateau-Salle, Laurent Greillier, Mir Ali Hoda, Walter Klepetko, Aude Lacourt, Phil McElnay, Nick A. Maskell, Luciano Mutti, Jean-Claude Pairon, Paul Van Schil, Jan P. van Meerbeeck, David Waller, Walter Weder, Giuseppe Cardillo, Paul Martin Putora Eur Respir J, 55 (6) 1900953; 10.1183/13993003.00953-2019

ERS guidelines

Withdrawal of inhaled corticosteroids in COPD: a European Respiratory Society guideline James D. Chalmers, Irena F. Laska, Frits M.E. Franssen, Wim Janssens, Ian Pavord, David Rigau, Melissa J. McDonnell, Nicolas Roche, Don D. Sin, Daiana Stolz, Samy Suissa, Jadwiga Wedzicha, Marc Miravitlles Eur Respir J, 55 (6) 2000351; 10.1183/13993003.00351-2020

Interstitial lung disease

The natural history of progressive fibrosing interstitial lung diseases Kevin K. Brown, Fernando J. Martinez, Simon L.F. Walsh, Victor J. Thannickal, Antje Prasse, Rozsa Schlenker-Herceg, Rainer-Georg Goeldner, Emmanuelle Clerisme-Beaty, Kay Tetzlaff, Vincent Cottin, Athol U. Wells Eur Respir J, 55 (6) 2000085; 10.1183/13993003.00085-2020

Bronchiectasis

Association between physical activity and risk of hospitalisation in bronchiectasis Victoria Alcaraz-Serrano, Elena Gimeno-Santos, Giulia Scioscia, Albert Gabarrús, Adria Navarro, Beatriz Herrero-Cortina, Rosanel Amaro, Laia Fernández-Barat, Antoni Torres Eur Respir J, 55 (6) 1902138; 10.1183/13993003.02138-2019

Basic science

Bioengineered airway epithelial grafts with mucociliary function based on collagen IV- and laminin-containing extracellular matrix scaffolds Nick J.I. Hamilton, Dani Do Hyang Lee, Kate H.C. Gowers, Colin R. Butler, Elizabeth F. Maughan, Benjamin Jevans, Jessica C. Orr, Conor J. McCann, Alan J. Burns, Sheila MacNeil, Martin A. Birchall, Christopher O'Callaghan, Robert E. Hynds, Sam M. Janes Eur Respir J, 55 (6) 1901200; 10.1183/13993003.01200-2019
TRIM33 prevents pulmonary fibrosis by impairing TGF-ß1 signalling Pierre-Marie Boutanquoi, Olivier Burgy, Guillaume Beltramo, Pierre-Simon Bellaye, Lucile Dondaine, Guillaume Marcion, Lenny Pommerolle, Aurélie Vadel, Maximilien Spanjaard, Oleg Demidov, Arnaud Mailleux, Bruno Crestani, Martin Kolb, Carmen Garrido, Françoise Goirand, Philippe Bonniaud Eur Respir J, 55 (6) 1901346; 10.1183/13993003.01346-2019

Pulmonary hypertension

Persistent exercise intolerance after pulmonary endarterectomy for chronic thromboembolic pulmonary hypertension Dieuwertje Ruigrok, Lilian J. Meijboom, Esther J. Nossent, Anco Boonstra, Natalia J. Braams, Jessie van Wezenbeek, Frances S. de Man, J. Tim Marcus, Anton Vonk Noordegraaf, Petr Symersky, Harm-Jan Bogaard Eur Respir J, 55 (6) 2000109; 10.1183/13993003.00109-2020
Mild parenchymal lung disease and/or low diffusion capacity impacts survival and treatment response in patients diagnosed with idiopathic pulmonary arterial hypertension Robert A. Lewis, A.A. Roger Thompson, Catherine G. Billings, Athanasios Charalampopoulos, Charlie A. Elliot, Neil Hamilton, Catherine Hill, Judith Hurdman, Smitha Rajaram, Ian Sabroe, Andy J. Swift, David G. Kiely, Robin Condliffe Eur Respir J, 55 (6) 2000041; 10.1183/13993003.00041-2020

Respiratory intensive care

Low-cost, easy-to-build noninvasive pressure support ventilator for under-resourced regions: open source hardware description, performance and feasibility testing Onintza Garmendia, Miguel A. Rodríguez-Lazaro, Jorge Otero, Phuong Phan, Alexandrina Stoyanova, Anh Tuan Dinh-Xuan, David Gozal, Daniel Navajas, Josep M. Montserrat, Ramon Farré Eur Respir J, 55 (6) 2000846; 10.1183/13993003.00846-2020

Infectious disease

Clinical characteristics and outcomes of hospitalised patients with COVID-19 treated in Hubei (epicentre) and outside Hubei (non-epicentre): a nationwide analysis of China Wen-hua Liang, Wei-jie Guan, Cai-chen Li, Yi-min Li, Heng-rui Liang, Yi Zhao, Xiao-qing Liu, Ling Sang, Ru-chong Chen, Chun-li Tang, Tao Wang, Wei Wang, Qi-hua He, Zi-sheng Chen, Sook-San Wong, Mark Zanin, Jun Liu, Xin Xu, Jun Huang, Jian-fu Li, Li-min Ou, Bo Cheng, Shan Xiong, Zhan-hong Xie, Zheng-yi Ni, Yu Hu, Lei Liu, Hong Shan, Chun-liang Lei, Yi-xiang Peng, Li Wei, Yong Liu, Ya-hua Hu, Peng Peng, Jian-ming Wang, Ji-yang Liu, Zhong Chen, Gang Li, Zhi-jian Zheng, Shao-qin Qiu, Jie Luo, Chang-jiang Ye, Shao-yong Zhu, Lin-ling Cheng, Feng Ye, Shi-yue Li, Jin-ping Zheng, Nuo-fu Zhang, Nan-shan Zhong, Jian-xing He Eur Respir J, 55 (6) 2000562; 10.1183/13993003.00562-2020
Nosocomial outbreak of COVID-19 pneumonia in Wuhan, China Xiaorong Wang, Qiong Zhou, Yukun He, Lingbo Liu, Xinqian Ma, Xiaoshan Wei, Nanchuan Jiang, Limei Liang, Yali Zheng, Ling Ma, Yu Xu, Dong Yang, Jianchu Zhang, Bohan Yang, Ning Jiang, Tao Deng, Bingbing Zhai, Yang Gao, Wenxuan Liu, Xinghua Bai, Tao Pan, Guoqing Wang, Yujun Chang, Zhi Zhang, Huanzhong Shi, Wan-Li Ma, Zhancheng Gao Eur Respir J, 55 (6) 2000544; 10.1183/13993003.00544-2020

Sleep medicine

Morphine alters respiratory control but not other key obstructive sleep apnoea phenotypes: a randomised trial Rodrigo T. Martins, Jayne C. Carberry, David Wang, Luke Rowsell, Ronald R. Grunstein, Danny J. Eckert Eur Respir J, 55 (6) 1901344; 10.1183/13993003.01344-2019

Asthma and COPD

Population-based case-finding to identify subjects with undiagnosed asthma or COPD Matthew Preteroti, G. Alex Whitmore, Katherine L. Vandemheen, J. Mark FitzGerald, Catherine Lemière, Louis-Philippe Boulet, Erika Penz, Stephen K. Field, Samir Gupta, R. Andrew McIvor, Irvin Mayers, Paul Hernandez, Diane Lougheed, Martha Ainslie, Christopher Licskai, Tanweer Azher, Ian Fraser, Masoud Mahdavian, Shawn D. Aaron Eur Respir J, 55 (6) 2000024; 10.1183/13993003.00024-2020

Asthma

Mepolizumab in a population with severe eosinophilic asthma and corticosteroid dependence: results from a French early access programme Camille Taillé, Pascal Chanez, Gilles Devouassoux, Alain Didier, Christophe Pison, Gilles Garcia, Jeremy Charriot, Stéphane Bouée, Alina Gruber, Celine Pribil, Arnaud Bourdin, Marc Humbert Eur Respir J, 55 (6) 1902345; 10.1183/13993003.02345-2019
Maternal smoking during pregnancy affects adult onset of asthma in offspring: a follow up from birth to age 46 years Sanna Toppila-Salmi, Annika T. Luukkainen, Baizhuang Xu, Jussi Lampi, Juha Auvinen, Kishor Dhaygude, Marjo-Riitta Järvelin, Juha Pekkanen Eur Respir J, 55 (6) 1901857; 10.1183/13993003.01857-2019
Oral corticosteroid prescription patterns for asthma in France, Germany, Italy and the UK Trung N. Tran, Elizabeth King, Rajiv Sarkar, Cassandra Nan, Annalisa Rubino, Caroline O'Leary, Ruvimbo Muzwidzwa, Laura Belton, Jennifer K. Quint Eur Respir J, 55 (6) 1902363; 10.1183/13993003.02363-2019

State of the Art

Personal strategies to minimise effects of air pollution on respiratory health: advice for providers, patients and the public Christopher Carlsten, Sundeep Salvi, Gary W.K. Wong, Kian Fan Chung Eur Respir J, 55 (6) 1902056; 10.1183/13993003.02056-2019

Reviews

Diagnosis of chronic thromboembolic pulmonary hypertension after acute pulmonary embolism Fredrikus A. Klok, Francis Couturaud, Marion Delcroix, Marc Humbert Eur Respir J, 55 (6) 2000189; 10.1183/13993003.00189-2020
*Clinical considerations in individuals with a₁-antitrypsin PISZ genotype** Gerard N. McElvaney, Robert A. Sandhaus, Marc Miravitlles, Gerard M. Turino, Niels Seersholm, Marion Wencker, Robert A. Stockley Eur Respir J, 55 (6) 1902410; 10.1183/13993003.02410-2019
The importance of interventional timing in the bleomycin model of pulmonary fibrosis Philipp Kolb, Chandak Upagupta, Megan Vierhout, Ehab Ayaub, Pierre Simon Bellaye, Jack Gauldie, Chiko Shimbori, Mark Inman, Kjetil Ask, Martin R.J. Kolb Eur Respir J, 55 (6) 1901105; 10.1183/13993003.01105-2019
Current status of cell-based therapies for respiratory virus infections: applicability to COVID-19 Maroun Khoury, Jimena Cuenca, Fernanda F. Cruz, Fernando E. Figueroa, Patricia R.M. Rocco, Daniel J. Weiss Eur Respir J, 55 (6) 2000858; 10.1183/13993003.00858-2020

Research letters

The value of chest CT as a COVID-19 screening tool in children Peter J.F.M. Merkus, Willemijn M. Klein Eur Respir J, 55 (6) 2001241; 10.1183/13993003.01241-2020
Type II conventional dendritic cells of asthmatic patients with frequent exacerbations have an altered phenotype and frequency Heleen Vroman, Irma Tindemans, Melanie Lukkes, Menno van Nimwegen, Geertje M. de Boer, Gerdien A. Tramper-Stranders, Gert-Jan Braunstahl, Rudi W. Hendriks, Mirjam Kool Eur Respir J, 55 (6) 1900859; 10.1183/13993003.00859-2019
Rape, asthma and dysfunctional breathing Robert J. Hancox, Jane Morgan, Nigel Dickson, Jennie Connor, Joanne M. Baxter Eur Respir J, 55 (6) 1902455; 10.1183/13993003.02455-2019
Sleep apnoea management in Europe during the COVID-19 pandemic: data from the European Sleep Apnoea Database (ESADA) Ludger Grote, Walter T. McNicholas, Jan Hedner Eur Respir J, 55 (6) 2001323; 10.1183/13993003.01323-2020
Novel coronavirus infection in newborn babies aged <28 days in China Zhi-Jiang Zhang, Xue-Jie Yu, Tao Fu, Yu Liu, Yan Jiang, Bing Xiang Yang, Yongyi Bi Eur Respir J, 55 (6) 2000697; 10.1183/13993003.00697-2020
Abnormal pulmonary function in COVID-19 patients at time of hospital discharge Xiaoneng Mo, Wenhua Jian, Zhuquan Su, Mu Chen, Hui Peng, Ping Peng, Chunliang Lei, Ruchong Chen, Nanshan Zhong, Shiyue Li Eur Respir J, 55 (6) 2001217; 10.1183/13993003.01217-2020
Transition from intravenous epoprostenol to selexipag in pulmonary arterial hypertension: a word of caution Kenichi Yanaka, Alicia Guillien, Thibaud Soumagne, Justin Benet, Nicolas Piliero, François Picard, Christophe Pison, Olivier Sitbon, Hélène Bouvaist, Bruno Degano Eur Respir J, 55 (6) 1902418; 10.1183/13993003.02418-2019
First heterozygous NOP10 mutation in familial pulmonary fibrosis Caroline Kannengiesser, Effrosyni D. Manali, Patrick Revy, Isabelle Callebaut, Ibrahima Ba, Adrien Borgel, Claire Oudin, Aggeliki Haritou, Lykourgos Kolilekas, Katerina Malagari, Raphael Borie, Elodie Lainey, Catherine Boileau, Bruno Crestani, Spyros A. Papiris Eur Respir J, 55 (6) 1902465; 10.1183/13993003.02465-2019
Serial sputum induction in nontuberculous mycobacterial pulmonary disease Michael R. Holt, Shannon H. Kasperbauer, Charles L. Daley Eur Respir J, 55 (6) 1902196; 10.1183/13993003.02196-2019
No indication of insulin resistance in idiopathic pulmonary arterial hypertension with preserved physical activity Bence M. Nagy, Gabor Kovacs, Adrienn Tornyos, Eva Svehlikova, Vasile Foris, Chandran Nagaraj, Grazyna Kwapiszewska, Thomas R. Pieber, Andrea Olschewski, Horst Olschewski Eur Respir J, 55 (6) 1901228; 10.1183/13993003.01228-2019
Maternal iron supplementation in pregnancy and asthma in the offspring: follow-up of a randomised trial in Finland Seif O. Shaheen, Mika Gissler, Graham Devereux, Maijaliisa Erkkola, Tarja I. Kinnunen, Harry Mcardle, Aziz Sheikh, Elina Hemminki, Bright I. Nwaru Eur Respir J, 55 (6) 1902335; 10.1183/13993003.02335-2019
Bedaquiline resistance in drug-resistant tuberculosis HIV co-infected patients Camus Nimmo, James Millard, Kayleen Brien, Sashen Moodley, Lucy van Dorp, Keeren Lutchminarain, Allison Wolf, Alison D. Grant, Francois Balloux, Alexander S. Pym, Nesri Padayatchi, Max O'Donnell Eur Respir J, 55 (6) 1902383; 10.1183/13993003.02383-2019
Increased reporting of fatal pneumonitis associated with immune checkpoint inhibitors: a WHO pharmacovigilance database analysis Melissa Y.Y. Moey, Paul Gougis, Vincent Goldschmidt, Douglas B. Johnson, Bénédicte Lebrun-Vignes, Javid Moslehi, Jacques Cadranel, Joe-Elie Salem Eur Respir J, 55 (6) 2000038; 10.1183/13993003.00038-2020

Correspondence

Will children reveal their secret? The coronavirus dilemma George James Porter Eur Respir J, 55 (6) 2001382; 10.1183/13993003.01382-2020
Will children reveal their secret? The coronavirus dilemma Fabio Midulla, Luca Cristiani, Enrica Mancino Eur Respir J, 55 (6) 2001617; 10.1183/13993003.01617-2020
To compare the incomparable: COVID-19 pneumonia and high-altitude disease Giacomo Strapazzon, Matthias P. Hilty, Pierre Bouzat, Lorenza Pratali, Hermann Brugger, Simon Rauch Eur Respir J, 55 (6) 2001362; 10.1183/13993003.01362-2020
Universal use of face masks for success against COVID-19: evidence and implications for prevention policies Susanna Esposito, Nicola Principi, Chi Chi Leung, Giovanni Battista Migliori Eur Respir J, 55 (6) 2001260; 10.1183/13993003.01260-2020
Ventilation–perfusion SPECT versus CTPA in young adult females with suspected pulmonary embolism Sofie Lindskov Hansen, Robin de Nijs, Jann Mortensen, Ronan M.G. Berg Eur Respir J, 55 (6) 2000448; 10.1183/13993003.00448-2020
The optimal imaging test for diagnosis of acute pulmonary embolism: a second chance for lung scintigraphy? Stavros V. Konstantinides Eur Respir J, 55 (6) 2001426; 10.1183/13993003.01426-2020
Arterial hypertension and the risk of severity and mortality of COVID-19 Carlos Enrique Leiva Sisnieguez, Walter Gastón Espeche, Martín Rogelio Salazar Eur Respir J, 55 (6) 2001148; 10.1183/13993003.01148-2020
Cardiovascular comorbidity and its impact on patients with COVID-19 Wei-jie Guan, Wen-hua Liang, Jian-xing He, Nan-shan Zhong Eur Respir J, 55 (6) 2001227; 10.1183/13993003.01227-2020
COVID-19 and smoking: is nicotine the hidden link? Patrizia Russo, Stefano Bonassi, Robertina Giacconi, Marco Malavolta, Carlo Tomino, Fabrizio Maggi Eur Respir J, 55 (6) 2001116; 10.1183/13993003.01116-2020
COVID-19 and nicotine as a mediator of ACE-2 Janice M. Leung, Chen Xi Yang, Don D. Sin Eur Respir J, 55 (6) 2001261; 10.1183/13993003.01261-2020
Current smoking is not associated with COVID-19 Marco Rossato, Lucia Russo, Sara Mazzocut, Angelo Di Vincenzo, Paola Fioretto, Roberto Vettor Eur Respir J, 55 (6) 2001290; 10.1183/13993003.01290-2020
Reply to: “Current smoking is not associated with COVID-19” Janice M. Leung, Chen Xi Yang, Don D. Sin Eur Respir J, 55 (6) 2001340; 10.1183/13993003.01340-2020
The looming threat of bedaquiline resistance in tuberculosis Chen-Yuan Chiang, Arnaud Trébucq, Alberto Piubello, Hans L. Rieder, Valérie Schwoebel, Armand Van Deun Eur Respir J, 55 (6) 2000718; 10.1183/13993003.00718-2020

Erratum

“The effect of exacerbation history on outcomes in the IMPACT trial.” David M.G. Halpin, Mark T. Dransfield, MeiLan K. Han, C. Elaine Jones, Sally Kilbride, Peter Lange, David A. Lipson, David A. Lomas, Fernando J. Martinez, Steve Pascoe, Dave Singh, Robert Wise and Gerard J. Criner. Eur Respir J 2020; 55: 1901921. Eur Respir J, 55 (6) 1951921; 10.1183/13993003.51921-2019