European Respiratory Journal

The ERJ publishes clinical and experimental work relating to all aspects of adult and paediatric respiratory medicine, including cell biology, epidemiology, immunology, oncology, pathophysiology, imaging, occupational medicine, intensive care, sleep medicine and thoracic surgery. In addition to original research material, the ERJ also publishes editorial commentaries, reviews, short research letters and correspondence to the editor. Articles are published continuously and collected into 12 monthly issues in two volumes per year.

December

Podcast

ERJ December Podcast: Tobacco harm reduction Eur Respir J, 54 (6) 19E5406; 10.1183/13993003.E5406-2019

Editorials

ERS and tobacco harm reduction Charlotta Pisinger, Elif Dagli, Filippos T. Filippidis, Linnea Hedman, Christer Janson, Stelios Loukides, Sofia Ravara, Isabel Saraiva, Jørgen Vestbo Eur Respir J, 54 (6) 1902009; 10.1183/13993003.02009-2019
From ARIA guidelines to the digital transformation of health in rhinitis and asthma multimorbidity Jean Bousquet, Josep M. Anto, Claus Bachert, Sinthia Bosnic-Anticevich, Marina Erhola, Tari Haahtela, Peter W. Hellings, Piotr Kuna, Oliver Pfaar, Boleslaw Samolinski, Holger J. Schünemann, Aziz Sheikh, Dana Wallace Eur Respir J, 54 (6) 1901023; 10.1183/13993003.01023-2019
Macrolide combination therapy for hospitalised CAP patients? An individualised approach supported by machine learning Carolina Garcia-Vidal, Catia Cillóniz, Antoni Torres Eur Respir J, 54 (6) 1902111; 10.1183/13993003.02111-2019
Hot off the press: downregulation of PRMT1 for long-lasting effects of bronchial thermoplasty Siti Farah Rahmawati, Reinoud Gosens Eur Respir J, 54 (6) 1901898; 10.1183/13993003.01898-2019
Fatty airways: a source of good and bad fats? Christopher E. Brightling, Andrew B. Tobin, Graeme Milligan Eur Respir J, 54 (6) 1902060; 10.1183/13993003.02060-2019
The impact of marijuana smoking on lung function Robert J. Hancox, Malcolm R. Sears Eur Respir J, 54 (6) 1902065; 10.1183/13993003.02065-2019
Roles of HIF1 and HIF2 in pulmonary hypertension: it all depends on the context Gregory B. Waypa, Paul T. Schumacker Eur Respir J, 54 (6) 1901929; 10.1183/13993003.01929-2019
Standardisation of cardiopulmonary exercise testing in chronic lung diseases: summary of key findings from the ERS task force Thomas Radtke, Ioannis Vogiatzis, Don S. Urquhart, Pierantonio Laveneziana, Richard Casaburi, Helge Hebestreit Eur Respir J, 54 (6) 1901441; 10.1183/13993003.01441-2019

Tuberculosis

Surveillance of adverse events in the treatment of drug-resistant tuberculosis: first global report Sergey Borisov, Edvardas Danila, Andrei Maryandyshev, Margareth Dalcolmo, Skaidrius Miliauskas, Liga Kuksa, Selene Manga, Alena Skrahina, Saulius Diktanas, Luigi Ruffo Codecasa, Alena Aleksa, Judith Bruchfeld, Antoniya Koleva, Alberto Piubello, Zarir Farokh Udwadia, Onno W. Akkerman, Evgeny Belilovski, Enrique Bernal, Martin J. Boeree, Julen Cadiñanos Loidi, Qingshan Cai, Jose Joaquín Cebrian Gallardo, Masoud Dara, Edita Davidaviciene, Lina Davies Forsman, Jorge De Los Rios, Justin Denholm, Jacinta Drakšiene, Raquel Duarte, Seifeldin Eltaeb Elamin, Nadia Escobar Salinas, Maurizio Ferrarese, Alexey Filippov, Ana Garcia, José-María García-García, Ieva Gaudiesiute, Blagovesta Gavazova, Regina Gayoso, Roscio Gomez Rosso, Vygantas Gruslys, Gina Gualano, Wouter Hoefsloot, Jerker Jonsson, Elena Khimova, Heinke Kunst, Rafael Laniado-Laborín, Yang Li, Cecile Magis-Escurra, Vinicio Manfrin, Valentina Marchese, Elena Martínez Robles, Alberto Matteelli, Jesica Mazza-Stalder, Charalampos Moschos, Marcela Muñoz-Torrico, Hamdan Mustafa Hamdan, Birute Nakceriene, Laurent Nicod, Magnolia Nieto Marcos, Domingo Juan Palmero, Fabrizio Palmieri, Apostolos Papavasileiou, Marie-Christine Payen, Agostina Pontarelli, Sarai Quirós, Adrian Rendon, Laura Saderi, Agnese Šmite, Ivan Solovic, Mahamadou Bassirou Souleymane, Marina Tadolini, Martin van den Boom, Marisa Vescovo, Pietro Viggiani, Askar Yedilbayev, Rolandas Zablockis, Dmitry Zhurkin, Matteo Zignol, Dina Visca, Antonio Spanevello, José A. Caminero, Jan-Willem Alffenaar, Simon Tiberi, Rosella Centis, Lia D'Ambrosio, Emanuele Pontali, Giovanni Sotgiu, Giovanni Battista Migliori Eur Respir J, 54 (6) 1901522; 10.1183/13993003.01522-2019
Nationwide analysis of treatment outcomes in children and adolescents routinely treated for tuberculosis in the Netherlands Fajri Gafar, Natasha van't Boveneind-Vrubleuskaya, Onno W. Akkerman, Bob Wilffert, Jan-Willem C. Alffenaar Eur Respir J, 54 (6) 1901402; 10.1183/13993003.01402-2019

Pneumonia

Macrolide combination therapy for patients hospitalised with community-acquired pneumonia? An individualised approach supported by machine learning Rainer König, Xueqi Cao, Marcus Oswald, Christina Forstner, Gernot Rohde, Jan Rupp, Martin Witzenrath, Tobias Welte, Martin Kolditz, Mathias Pletz Eur Respir J, 54 (6) 1900824; 10.1183/13993003.00824-2019

Imaging

Diverse cardiopulmonary diseases are associated with distinct xenon magnetic resonance imaging signatures Ziyi Wang, Elianna A. Bier, Aparna Swaminathan, Kishan Parikh, John Nouls, Mu He, Joseph G. Mammarappallil, Sheng Luo, Bastiaan Driehuys, Sudarshan Rajagopal Eur Respir J, 54 (6) 1900831; 10.1183/13993003.00831-2019

Asthma

Does adherence to inhaled corticosteroids predict asthma-related outcomes over time? A cohort study Alexandra L. Dima, Eric van Ganse, Gertraud Stadler, Marijn de Bruin Eur Respir J, 54 (6) 1900901; 10.1183/13993003.00901-2019
Shared genetics of asthma and mental health disorders: a large-scale genome-wide cross-trait analysis Zhaozhong Zhu, Xi Zhu, Cong-Lin Liu, Huwenbo Shi, Sipeng Shen, Yunqi Yang, Kohei Hasegawa, Carlos A. Camargo, Liming Liang Eur Respir J, 54 (6) 1901507; 10.1183/13993003.01507-2019

Asthma and paediatrics

Diagnosis of asthma in children: the contribution of a detailed history and test results Carmen C.M. de Jong, Eva S.L. Pedersen, Rebeca Mozun, Myrofora Goutaki, Daniel Trachsel, Juerg Barben, Claudia E. Kuehni Eur Respir J, 54 (6) 1901326; 10.1183/13993003.01326-2019

Asthma and basic science

Bronchial thermoplasty decreases airway remodelling by blocking epithelium-derived heat shock protein-60 secretion and protein arginine methyltransferase-1 in fibroblasts Qingzhu Sun, Lei Fang, Michael Roth, Xuemei Tang, Eleni Papakonstantinou, Weiqi Zhai, Renaud Louis, Vincent Heinen, Florence N. Schleich, Shemin Lu, Spasenjia Savic, Michael Tamm, Daiana Stolz Eur Respir J, 54 (6) 1900300; 10.1183/13993003.00300-2019

Asthma and COPD

Fatty airways: implications for obstructive disease John G. Elliot, Graham M. Donovan, Kimberley C.W. Wang, Francis H.Y. Green, Alan L. James, Peter B. Noble Eur Respir J, 54 (6) 1900857; 10.1183/13993003.00857-2019

COPD

The pharmacogenomics of inhaled corticosteroids and lung function decline in COPD Ma'en Obeidat, Alen Faiz, Xuan Li, Maarten van den Berge, Nadia N. Hansel, Philippe Joubert, Ke Hao, Corry-Anke Brandsma, Nicholas Rafaels, Rasika Mathias, Ingo Ruczinski, Terri H. Beaty, Kathleen C. Barnes, S.F. Paul Man, Peter D. Paré, Don D. Sin Eur Respir J, 54 (6) 1900521; 10.1183/13993003.00521-2019

COPD and smoking

The effects of marijuana smoking on lung function in older people Wan C. Tan, Jean Bourbeau, Shawn D. Aaron, James C. Hogg, François Maltais, Paul Hernandez, Darcy D. Marciniuk, Kenneth R. Chapman, Teresa To, J. Mark FitzGerald, Brandie L. Walker, Jeremy Road, Liyun Zheng, Guohai Zhou, Trevor Yau, Andrea Benedetti, Denis O'Donnell, Don D. Sin Eur Respir J, 54 (6) 1900826; 10.1183/13993003.00826-2019

Lung biology

Suitable reference genes determination for real-time PCR using induced sputum samples Catherine Moermans, Esteban Deliege, Dimitri Pirottin, Christophe Poulet, Julien Guiot, Monique Henket, Jane da Silva, Renaud Louis Eur Respir J, 54 (6) 1800644; 10.1183/13993003.00644-2018

Pulmonary vascular disease

Suppression of HIF2 signalling attenuates the initiation of hypoxia-induced pulmonary hypertension Cheng-Jun Hu, Jens M. Poth, Hui Zhang, Amanda Flockton, Aya Laux, Sushil Kumar, Brittany McKeon, Gary Mouradian, Min Li, Suzette Riddle, Steven C. Pugliese, R. Dale Brown, Eli M. Wallace, Brian B. Graham, Maria G. Frid, Kurt R. Stenmark Eur Respir J, 54 (6) 1900378; 10.1183/13993003.00378-2019
Clinical phenotypes and outcomes of precapillary pulmonary hypertension of sickle cell disease Laurent Savale, Anoosha Habibi, François Lionnet, Bernard Maitre, Vincent Cottin, Xavier Jais, Ari Chaouat, Elise Artaud-Macari, Matthieu Canuet, Grégoire Prevot, Christelle Chantalat-Auger, David Montani, Olivier Sitbon, Fréderic Galacteros, Gérald Simonneau, Florence Parent, Pablo Bartolucci, Marc Humbert Eur Respir J, 54 (6) 1900585; 10.1183/13993003.00585-2019

ERJ Methods

Unravelling machine learning: insights in respiratory medicine Elsa Angelini, Simon Dahan, Anand Shah Eur Respir J, 54 (6) 1901216; 10.1183/13993003.01216-2019

Research letters

International trends in COPD mortality, 1995–2017 Joannie Lortet-Tieulent, Isabelle Soerjomataram, José Luis López-Campos, Julio Ancochea, Jan Willem Coebergh, Joan B. Soriano Eur Respir J, 54 (6) 1901791; 10.1183/13993003.01791-2019
Low agreement between mMRC rated by patients and clinicians: implications for practice Magnus Ekström, Sungwon Chang, Miriam J. Johnson, Belinda Fazekas, Slavica Kochovska, Chao Huang, David C. Currow Eur Respir J, 54 (6) 1901517; 10.1183/13993003.01517-2019
Pulmonary fibrosis linked to variants in the ACD gene, encoding the telomere protein TPP1 Thijs W. Hoffman, Joanne J. van der Vis, Jasper J. van der Smagt, Maarten P.G. Massink, Jan C. Grutters, Coline H.M. van Moorsel Eur Respir J, 54 (6) 1900809; 10.1183/13993003.00809-2019
The most beautiful COPD chart in the world: all together to end COPD! Joan B. Soriano, Julio Ancochea, Bartolomé R. Celli Eur Respir J, 54 (6) 1902047; 10.1183/13993003.02047-2019
Concomitant medications and clinical outcomes in idiopathic pulmonary fibrosis Michael Kreuter, David J. Lederer, Vincent Cottin, Nicolas Kahn, Brett Ley, Carlo Vancheri, Derek Weycker, Mark Atwood, Klaus-Uwe Kirchgaessler, Christopher J. Ryerson Eur Respir J, 54 (6) 1901188; 10.1183/13993003.01188-2019
Lumbar transcutaneous electrical nerve stimulation to improve exercise performance in COPD patients Tristan Bonnevie, Francis-Edouard Gravier, Guillaume Prieur, Yann Combret, David Debeaumont, Maxime Patout, Bouchra Lamia, Jean-François Muir, Clement Médrinal, Antoine Cuvelier Eur Respir J, 54 (6) 1900784; 10.1183/13993003.00784-2019
Giant cell interstitial pneumonia secondary to cobalt exposure from e-cigarette use Daffolyn Rachael Fels Elliott, Rupal Shah, Catherine Ann Hess, Brett Elicker, Travis S. Henry, Ana Maria Rule, Rui Chen, Mehdi Golozar, Kirk D. Jones Eur Respir J, 54 (6) 1901922; 10.1183/13993003.01922-2019
Effect of change of body position in spontaneous sleeping healthy infants on SF₆-based multiple breath washout Paul D. Robinson, Laszlo Kadar, Anders Lindblad, Per M. Gustafsson Eur Respir J, 54 (6) 1900259; 10.1183/13993003.00259-2019
Treatment of multidrug-resistant tuberculosis using therapeutic drug monitoring: first experiences with sub-300 mg linezolid dosages using in-house made capsules Mathieu S. Bolhuis, Tjip S. van der Werf, Huib A.M. Kerstjens, Wiel C.M. de Lange, Jan-Willem C. Alffenaar, Onno W. Akkerman Eur Respir J, 54 (6) 1900580; 10.1183/13993003.00580-2019
Increasing bronchiectasis prevalence in Germany, 2009–2017: a population-based cohort study Felix C. Ringshausen, Jessica Rademacher, Isabell Pink, Andrés de Roux, Lennart Hickstein, Tina Ploner, Tobias Welte, Roland Diel Eur Respir J, 54 (6) 1900499; 10.1183/13993003.00499-2019

Correspondence

Tracheomalacia and bronchomalacia in children: response to the ERS statement Suzanne Crowley, Kai-Håkon Carlsen Eur Respir J, 54 (6) 1902098; 10.1183/13993003.02098-2019
Tracheomalacia and bronchomalacia in children: response to the ERS statement Colin Wallis, Kostas Priftis, Anne Chang, Fabio Midulla, Jayesh Bhatt Eur Respir J, 54 (6) 1902271; 10.1183/13993003.02271-2019
Acute hypoxaemic respiratory failure in immunocompromised patients: abandon bronchoscopy or make it better? Matt S. Zinter, Guang-Shing Cheng Eur Respir J, 54 (6) 1901950; 10.1183/13993003.01950-2019
Acute hypoxaemic respiratory failure in immunocompromised patients: abandon bronchoscopy or make it better? Philippe R. Bauer, Sylvie Chevret, Elie Azoulay Eur Respir J, 54 (6) 1902177; 10.1183/13993003.02177-2019
Testing bronchodilator responsiveness Martin R. Miller Eur Respir J, 54 (6) 1902036; 10.1183/13993003.02036-2019
Testing bronchodilator responsiveness Christer Janson, Andrei Malinovschi, Andre F.S. Amaral, Simone Accordini, Jean Bousquet, A. Sonia Buist, Judith Garcia-Aymerich, Louisa Gnatiuc, Wan Tan, Kjell Torén, Torsten Zuberbier, Peter Burney Eur Respir J, 54 (6) 1902104; 10.1183/13993003.02104-2019

Call for papers

Call for papers on cystic fibrosis: a collaborative research session featuring the European Respiratory Journal, The Lancet Respiratory Medicine and the Journal of Cystic Fibrosis Eur Respir J, 54 (6) 1960001; 10.1183/13993003.60001-2019