ERJ Open Research

The journal was created to help fulfil the ERS objective to disseminate scientific and educational material to its members and to the medical community, but also to provide researchers with an affordable open access specialty journal in which to publish their work.

January

Breaking news

Influenza news from the frontline: what's happening? Anita K. Simonds ERJ Open Res, 4 (1) 00020-2018; 10.1183/23120541.00020-2018

Editorials

Advance care planning in severe COPD: it is time to engage with the future Stefan Andreas, Bernd Alt-Epping ERJ Open Res, 4 (1) 00009-2018; 10.1183/23120541.00009-2018
Let research leave you breathless, not physical exercise! Matteo Bonini, Omar S. Usmani ERJ Open Res, 4 (1) 00010-2018; 10.1183/23120541.00010-2018

Course report

The European Respiratory Society course on acute respiratory pandemics: how to plan for and manage them Adekunle Olatayo Adeoti, Sierk Marbus ERJ Open Res, 4 (1) 00156-2017; 10.1183/23120541.00156-2017

Messages from Milan

European Respiratory Society International Congress 2017: highlights from the Clinical Assembly Nicolas Kahn, Evgeni Mekov, Laura Fregonese, Vasileios Andrianopoulos, Frits M.E. Franssen, Aleksandar Grgic, Johan Coolen, Peter I. Bonta, Daniela Gompelmann, Jouke T. Annema, Paola Faverio, Francesco Bonella, Luke Daines, Hillary Pinnock, Janwillem Kocks, Felix Herth ERJ Open Res, 4 (1) 00134-2017; 10.1183/23120541.00134-2017

Research highlights from the 2017 ERS International Congress: airway diseases in focus Cecilia Andersson, Sara J. Bonvini, Peter Horvath, Eduardo Marquez, Imran Satia, Paul Kirkham, Florence Schleich, Marco Idzko, Reinoud Gosens, Jose Luis Lopez-Campos, Apostolos Bossios, Omar Usmani, Antonio Spanevello, Ian M. Adcock, Alexander G. Mathioudakis ERJ Open Res, 4 (1) 00163-2017; 10.1183/23120541.00163-2017

Series

COPD: time to improve its taxonomy? Bartolomé R. Celli, Alvar Agustí ERJ Open Res, 4 (1) 00132-2017; 10.1183/23120541.00132-2017

Review

An algorithmic approach for the treatment of severe uncontrolled asthma Eleftherios Zervas, Konstantinos Samitas, Andriana I. Papaioannou, Petros Bakakos, Stelios Loukides, Mina Gaga ERJ Open Res, 4 (1) 00125-2017; 10.1183/23120541.00125-2017

Study protocol

Rationale and design of the screening of pulmonary hypertension in systemic lupus erythematosus (SOPHIE) study Duo Huang, Yang-Yang Cheng, Pak-Hei Chan, Jojo Hai, Kai-Hang Yiu, Hung-Fat Tse, Ka-Lam Wong, Katherine Fan, Ying Wah Li, Woon-Leung Ng, Cheuk-Wan Yim, Cheuk-hon John Wong, Lai-Shan Tam, Priscilla C.H. Wong, Chi-Yuen Wong, Chup-Hei Ho, Alexander M.H. Leung, Chi-Chiu Mok, Ho Lam, Chak-Sing Lau, Tommy Cheung, Carmen Ho, Sharon W.Y. Law, Esther W. Chan, Li-Xue Yin, Wen-Sheng Yue, Toi Meng Mok, Mario Alberto Evora, Chung-Wah Siu ERJ Open Res, 4 (1) 00135-2017; 10.1183/23120541.00135-2017

Original articles

Pleural tuberculosis: medical thoracoscopy greatly increases the diagnostic accuracy Angelo Gianni Casalini, Pier Anselmo Mori, Maria Majori, Miriam Anghinolfi, Enrico Maria Silini, Letizia Gnetti, Federica Motta, Sandra Larini, Sara Montecchini, Roberta Pisi, Adriana Calderaro ERJ Open Res, 4 (1) 00046-2017; 10.1183/23120541.00046-2017
Effects of umeclidinium/vilanterol on exercise endurance in COPD: a randomised study John H. Riley, Chris J. Kalberg, Alison Donald, David A. Lipson, Muhammad Shoaib, Lee Tombs ERJ Open Res, 4 (1) 00073-2017; 10.1183/23120541.00073-2017
The pronounced high expression of discoidin domain receptor 2 in human interstitial lung diseases Huan Bian, Xiaowei Nie, Xin Bu, Feng Tian, Libo Yao, Jingyu Chen, Jin Su ERJ Open Res, 4 (1) 00138-2016; 10.1183/23120541.00138-2016
Upper airway involvement in bronchiectasis is marked by early onset and allergic features Michal Shteinberg, Najwan Nassrallah, Jenny Jrbashyan, Nechama Uri, Nili Stein, Yochai Adir ERJ Open Res, 4 (1) 00115-2017; 10.1183/23120541.00115-2017
Decrease in pulmonary function and oxygenation after lung resection Barbara Cristina Brocki, Elisabeth Westerdahl, Daniel Langer, Domingos S.R. Souza, Jan Jesper Andreasen ERJ Open Res, 4 (1) 00055-2017; 10.1183/23120541.00055-2017
Incidence and predictive factors of lung cancer in patients with idiopathic pulmonary fibrosis Eisuke Kato, Noboru Takayanagi, Yotaro Takaku, Naho Kagiyama, Tetsu Kanauchi, Takashi Ishiguro, Yutaka Sugita ERJ Open Res, 4 (1) 00111-2016; 10.1183/23120541.00111-2016
Supporting patients self-managing respiratory health: a qualitative study on the impact of the Breathe Easy voluntary group network Ferhana Hashem, Rowena Merritt ERJ Open Res, 4 (1) 00076-2017; 10.1183/23120541.00076-2017
Real-life experience of ceritinib in crizotinib-pretreated ALK+ advanced non-small cell lung cancer patients Jacques Cadranel, Alexis B. Cortot, Hervé Lena, Bertrand Mennecier, Pascal Do, Eric Dansin, Julien Mazieres, Christos Chouaid, Maurice Perol, Fabrice Barlesi, Gilles Robinet, Sylvie Friard, Luc Thiberville, Clarisse Audigier-Valette, Alain Vergnenegre, Virginie Westeel, Khemaies Slimane, Alexandru Buturuga, Denis Moro-Sibilot, Benjamin Besse ERJ Open Res, 4 (1) 00058-2017; 10.1183/23120541.00058-2017
Integrated respiratory and palliative care may improve outcomes in advanced lung disease Natasha Smallwood, Michelle Thompson, Matthew Warrender-Sparkes, Peter Eastman, Brian Le, Louis Irving, Jennifer Philip ERJ Open Res, 4 (1) 00102-2017; 10.1183/23120541.00102-2017
The clinical utility of lung clearance index in early cystic fibrosis lung disease is not impacted by the number of multiple-breath washout trials Rachel E. Foong, Alana J. Harper, Billy Skoric, Louise King, Lidija Turkovic, Miriam Davis, Charles C. Clem, Tim Rosenow, Stephanie D. Davis, Sarath Ranganathan, Graham L. Hall, Kathryn A. Ramsey ERJ Open Res, 4 (1) 00094-2017; 10.1183/23120541.00094-2017
OMNIgene.SPUTUM suppresses contaminants while maintaining Mycobacterium tuberculosis viability and obviates cold-chain transport Khalide Azam, Nureisha Cadir, Carla Madeira, Stephen H. Gillespie, Wilber Sabiiti ERJ Open Res, 4 (1) 00074-2017; 10.1183/23120541.00074-2017
Do-not-resuscitate orders as part of advance care planning in patients with COPD Jo Raskin, Kristina Vermeersch, Stephanie Everaerts, Pascal Van Bleyenbergh, Wim Janssens ERJ Open Res, 4 (1) 00116-2017; 10.1183/23120541.00116-2017
Leaks during multiple-breath washout: characterisation and influence on outcomes Nina Lenherr, Kathryn A. Ramsey, Kerstin Jost, Linn Hornwall, Florian Singer, Sophie Yammine, Philipp Latzin ERJ Open Res, 4 (1) 00012-2017; 10.1183/23120541.00012-2017
Factors influencing readthrough therapy for frequent cystic fibrosis premature termination codons Iwona Pranke, Laure Bidou, Natacha Martin, Sandra Blanchet, Aurélie Hatton, Sabrina Karri, David Cornu, Bruno Costes, Benoit Chevalier, Danielle Tondelier, Emmanuelle Girodon, Matthieu Coupet, Aleksander Edelman, Pascale Fanen, Olivier Namy, Isabelle Sermet-Gaudelus, Alexandre Hinzpeter ERJ Open Res, 4 (1) 00080-2017; 10.1183/23120541.00080-2017
Reproducibility of hypercapnic ventilatory response measurements with steady-state and rebreathing methods Denise C. Mannée, Timon M. Fabius, Michiel Wagenaar, Michiel M.M. Eijsvogel, Frans H.C. de Jongh ERJ Open Res, 4 (1) 00141-2017; 10.1183/23120541.00141-2017
Ventilator flow data predict bronchopulmonary dysplasia in extremely premature neonates Mariann H. Bentsen, Trond Markestad, Thomas Halvorsen ERJ Open Res, 4 (1) 00099-2017; 10.1183/23120541.00099-2017
The potentially beneficial central nervous system activity profile of ivacaftor and its metabolites Elena K. Schneider, Rachel M. McQuade, Vincenzo C. Carbone, Felisa Reyes-Ortega, John W. Wilson, Brenda Button, Ayame Saito, Daniel P. Poole, Daniel Hoyer, Jian Li, Tony Velkov ERJ Open Res, 4 (1) 00127-2017; 10.1183/23120541.00127-2017
Multiple inflammasomes may regulate the interleukin-1-driven inflammation in protracted bacterial bronchitis Alice C-H. Chen, Hai B. Tran, Yang Xi, Stephanie T. Yerkovich, Katherine J. Baines, Susan J. Pizzutto, Melanie Carroll, Avril A.B. Robertson, Matthew A. Cooper, Kate Schroder, Jodie L. Simpson, Peter G. Gibson, Greg Hodge, Ian B. Masters, Helen M. Buntain, Helen L. Petsky, Samantha J. Prime, Anne B. Chang, Sandra Hodge, John W. Upham ERJ Open Res, 4 (1) 00130-2017; 10.1183/23120541.00130-2017
Multidimensional fatigue in pulmonary hypertension: prevalence, severity and predictors Todd M. Tartavoulle, Aryn C. Karpinski, Andrew Aubin, Benzi M. Kluger, Oliver Distler, Lesley Ann Saketkoo ERJ Open Res, 4 (1) 00079-2017; 10.1183/23120541.00079-2017
Physicians' perspectives on communication and decision making in clinical encounters for treatment of latent tuberculosis infection Claudia C. Dobler, Sinthia Bosnic-Anticevich, Carol L. Armour ERJ Open Res, 4 (1) 00146-2017; 10.1183/23120541.00146-2017

Original research letters

Cytomegalovirus-associated pulmonary exacerbation in patients with cystic fibrosis Akhil Sawant, Giulia Spoletini, Paul Whitaker, Christine Etherington, Ian Clifton, Daniel Peckham ERJ Open Res, 4 (1) 00111-2017; 10.1183/23120541.00111-2017
Time to change the single-centre approach to management of patients with tuberculosis: a novel network platform with automatic data import and data sharing Niccolò Riccardi, Barbara Giannini, Maria Lucia Borghesi, Lucia Taramasso, Elena Cattaneo, Giovanni Cenderello, Federica Toscanini, Mauro Giacomini, Emanuele Pontali, Giovanni Cassola, Claudio Viscoli, Antonio Di Biagio ERJ Open Res, 4 (1) 00108-2017; 10.1183/23120541.00108-2017
An educational initiative to improve the team-based care of patients with idiopathic pulmonary fibrosis Evans R. Fernández Pérez, Pearlanne Zelarney, Shirley Thomas, Deborah A. Shoop, Jessica L. Munson, Kelsey D. Johnson, Matthew E. Stern, Sarah Meadows ERJ Open Res, 4 (1) 00093-2017; 10.1183/23120541.00093-2017
Effect of cladribine therapy on lung cysts in pulmonary Langerhans cell histiocytosis Mouhamad Nasser, Julie Traclet, Vincent Cottin ERJ Open Res, 4 (1) 00089-2017; 10.1183/23120541.00089-2017
The annual prognostic ability of FACED and E-FACED scores to predict mortality in patients with bronchiectasis David de la Rosa Carrillo, Rodrigo Athanazio, Rosa Maria Girón Moreno, Luis Máiz Carro, Casilda Olveira, Javier de Gracia, Montserrat Vendrell, Concepción Prados Sánchez, Georgina Gramblicka, Monica Corso Pereira, Fernando Lundgren, Mara Fernandes De Figueiredo, Francisco Arancibia, Samia Rached, Miguel-Angel Martínez-Garcia ERJ Open Res, 4 (1) 00139-2017; 10.1183/23120541.00139-2017
RON tyrosine kinase mutations in brain metastases from lung cancer Melissa Milan, Silvia Benvenuti, Alice Maria Balderacchi, Anna Rita Virzì, Alessandra Gentile, Rebecca Senetta, Paola Cassoni, Paolo Maria Comoglio, Giulia Maria Stella ERJ Open Res, 4 (1) 00083-2017; 10.1183/23120541.00083-2017
Pseudoneutropenia in lymphangioleiomyomatosis (LAM) patients receiving sirolimus: evaluation in a 100 patient cohort Vissagan Gopalakrishnan, Amanda M. Jones, Patricia Julien-Williams, Tania Machado, Robert L. Danner, Jeffrey J. Swigris, Robert Paine, Jay N. Lozier, Joel Moss ERJ Open Res, 4 (1) 00121-2017; 10.1183/23120541.00121-2017
Peripheral alveolar nitric oxide concentration reflects alveolar inflammation in autoimmune pulmonary alveolar proteinosis Taizou Hirano, Shinya Ohkouchi, Naoki Tode, Makoto Kobayashi, Manabu Ono, Teruyuki Satoh, Yoichiro Mitsuishi, Akira Watanabe, Masao Tabata, Toshiya Irokawa, Hiromasa Ogawa, Hisatoshi Sugiura, Toshiaki Kikuchi, Keiichi Akasaka, Ryushi Tazawa, Yoshikazu Inoue, Koh Nakata, Hajime Kurosawa, Masakazu Ichinose ERJ Open Res, 4 (1) 00071-2017; 10.1183/23120541.00071-2017