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March

The CICERO (Collaboration In COPD ExaceRbatiOns) Clinical Research Collaboration Wim Janssens, Mona Bafadhel Eur Respir J, 55 (3) 2000079; 10.1183/13993003.00079-2020
The case for assessing the full value of new tuberculosis vaccines Nebiat Gebreselassie, Raymond Hutubessy, Johan Vekemans, Saskia den Boon, Tereza Kasaeva, Matteo Zignol Eur Respir J, 55 (3) 1902414; 10.1183/13993003.02414-2019
From pests to tests: training rats to diagnose tuberculosis Lena Fiebig, Negussie Beyene, Robert Burny, Cynthia D. Fast, Christophe Cox, Georgies F. Mgode Eur Respir J, 55 (3) 1902243; 10.1183/13993003.02243-2019
Suboptimal CPAP adherence: half a loaf is better than no bread at all Martha E. Billings, Patrick Lévy, Najib Ayas Eur Respir J, 55 (3) 2000144; 10.1183/13993003.00144-2020
Maternal nutrition and child respiratory outcomes: paradigms of lung health and disease Corrine Hanson, Emily Brigham Eur Respir J, 55 (3) 1902437; 10.1183/13993003.02437-2019
Demystifying morphomolecular alterations of vasculature in interstitial lung diseases Toyoshi Yanagihara, Kirk D. Jones Eur Respir J, 55 (3) 1902446; 10.1183/13993003.02446-2019
Tips for success in pulmonary hypertension treatment: progress in isolating endothelial cells from pulmonary artery catheters Andrea L. Frump, Tim Lahm Eur Respir J, 55 (3) 2000122; 10.1183/13993003.00122-2020
Small airways and early origins of COPD: pathobiological and epidemiological considerations Francesca Polverino, Joan B. Soriano Eur Respir J, 55 (3) 1902457; 10.1183/13993003.02457-2019
Treatable traits: a step closer to the “holy grail” of asthma control? William W. Busse Eur Respir J, 55 (3) 2000002; 10.1183/13993003.00002-2020
The continued hunt for the elusive standard short regimen for treatment of multidrug-resistant tuberculosis J. Peter Cegielski, Payam Nahid, Giovanni Sotgiu Eur Respir J, 55 (3) 2000224; 10.1183/13993003.00224-2020
When it all comes down to pressure: right ventricular ejection fraction at cardiac catheterisation Robert Naeije, Manuel J. Richter, Rebecca Vanderpool, Khodr Tello Eur Respir J, 55 (3) 1902341; 10.1183/13993003.02341-2019
Effects of suboptimal adherence of CPAP therapy on symptoms of obstructive sleep apnoea: a randomised, double-blind, controlled trial Thomas Gaisl, Protazy Rejmer, Sira Thiel, Sarah R. Haile, Martin Osswald, Malgorzata Roos, Konrad E. Bloch, John R. Stradling, Malcolm Kohler Eur Respir J, 55 (3) 1901526; 10.1183/13993003.01526-2019
Gefapixant in two randomised dose-escalation studies in chronic cough Jaclyn A. Smith, Michael M. Kitt, Peter Butera, Steven A. Smith, Yuping Li, Zhi Jin Xu, Kimberley Holt, Shilpi Sen, Mandel R. Sher, Anthony P. Ford Eur Respir J, 55 (3) 1901615; 10.1183/13993003.01615-2019
The effect of HIV-associated tuberculosis, tuberculosis-IRIS and prednisone on lung function Cari Stek, Brian Allwood, Elsa Du Bruyn, Jozefien Buyze, Charlotte Schutz, Friedrich Thienemann, Adele Lombard, Robert J. Wilkinson, Graeme Meintjes, Lutgarde Lynen Eur Respir J, 55 (3) 1901692; 10.1183/13993003.01692-2019
Mediterranean diet during pregnancy and childhood respiratory and atopic outcomes: birth cohort study Annabelle Bédard, Kate Northstone, A. John Henderson, Seif O. Shaheen Eur Respir J, 55 (3) 1901215; 10.1183/13993003.01215-2019
Morphomolecular motifs of pulmonary neoangiogenesis in interstitial lung diseases Maximilian Ackermann, Helge Stark, Lavinia Neubert, Stephanie Schubert, Paul Borchert, Friedemann Linz, Willi L. Wagner, Wolfram Stiller, Mark Wielpütz, Anne Hoefer, Axel Haverich, Steven J. Mentzer, Harshit R. Shah, Tobias Welte, Mark Kuehnel, Danny Jonigk Eur Respir J, 55 (3) 1900933; 10.1183/13993003.00933-2019
Culture of pulmonary artery endothelial cells from pulmonary artery catheter balloon tips: considerations for use in pulmonary vascular disease Corey E. Ventetuolo, Jason M. Aliotta, Julie Braza, Havovi Chichger, Mark Dooner, Donald McGuirl, Christopher J. Mullin, Julie Newton, Mandy Pereira, Amy Princiotto, Peter J. Quesenberry, Thomas Walsh, Mary Whittenhall, James R. Klinger, Elizabeth O. Harrington Eur Respir J, 55 (3) 1901313; 10.1183/13993003.01313-2019
Connexin-43 is a promising target for pulmonary hypertension due to hypoxaemic lung disease Claire Bouvard, Nafiisha Genet, Carole Phan, Baptiste Rode, Raphaël Thuillet, Ly Tu, Paul Robillard, Marilyne Campagnac, Raffaella Soleti, Eric Dumas De La Roque, Frédéric Delcambre, Laurent Cronier, Thibaud Parpaite, Elise Maurat, Patrick Berger, Jean-Pierre Savineau, Roger Marthan, Christophe Guignabert, Véronique Freund-Michel, Christelle Guibert Eur Respir J, 55 (3) 1900169; 10.1183/13993003.00169-2019
Association of asthma and smoking with lung function impairment in adolescence and early adulthood: the Isle of Wight Birth Cohort Study S. Hasan Arshad, Claire Hodgekiss, John W. Holloway, Ramesh Kurukulaaratchy, Wilfried Karmaus, Hongmei Zhang, Graham Roberts Eur Respir J, 55 (3) 1900477; 10.1183/13993003.00477-2019
Targeting treatable traits in severe asthma: a randomised controlled trial Vanessa M. McDonald, Vanessa L. Clark, Laura Cordova-Rivera, Peter A.B. Wark, Katherine J. Baines, Peter G. Gibson Eur Respir J, 55 (3) 1901509; 10.1183/13993003.01509-2019
The safety of isoniazid tuberculosis preventive treatment in pregnant and postpartum women: systematic review and meta-analysis Yohhei Hamada, Carmen Figueroa, Mario Martín-Sánchez, Dennis Falzon, Avinash Kanchar Eur Respir J, 55 (3) 1901967; 10.1183/13993003.01967-2019
Screening and treatment of tuberculosis among pregnant women in Stockholm, Sweden, 2016–2017 Gabrielle Fröberg, Lena Jansson, Katherine Nyberg, Birgitta Obasi, Katarina Westling, Ingela Berggren, Judith Bruchfeld Eur Respir J, 55 (3) 1900851; 10.1183/13993003.00851-2019
Increased risk of active tuberculosis during pregnancy and postpartum: a register-based cohort study in Sweden Jerker Jonsson, Sharon Kühlmann-Berenzon, Ingela Berggren, Judith Bruchfeld Eur Respir J, 55 (3) 1901886; 10.1183/13993003.01886-2019
Treatment with isoniazid or rifampin for latent tuberculosis infection: population-based study of hepatotoxicity, completion and costs Lisa A. Ronald, J. Mark FitzGerald, Gillian Bartlett-Esquilant, Kevin Schwartzman, Andrea Benedetti, Jean-François Boivin, Dick Menzies Eur Respir J, 55 (3) 1902048; 10.1183/13993003.02048-2019
Standardised shorter regimens versus individualised longer regimens for rifampin- or multidrug-resistant tuberculosis Syed Abidi, Jay Achar, Mourtala Mohamed Assao Neino, Didi Bang, Andrea Benedetti, Sarah Brode, Jonathon R. Campbell, Esther C. Casas, Francesca Conradie, Gunta Dravniece, Philipp du Cros, Dennis Falzon, Ernesto Jaramillo, Christopher Kuaban, Zhiyi Lan, Christoph Lange, Pei Zhi Li, Mavluda Makhmudova, Aung Kya Jai Maug, Dick Menzies, Giovanni Battista Migliori, Ann Miller, Bakyt Myrzaliev, Norbert Ndjeka, Jürgen Noeske, Nargiza Parpieva, Alberto Piubello, Valérie Schwoebel, Welile Sikhondze, Rupak Singla, Mahamadou Bassirou Souleymane, Arnaud Trébucq, Armand Van Deun, Kerri Viney, Karin Weyer, Betty Jingxuan Zhang, Faiz Ahmad Khan Eur Respir J, 55 (3) 1901467; 10.1183/13993003.01467-2019
Donor surfactant protein A2 polymorphism and lung transplant survival Frank D'Ovidio, Joanna Floros, Beatrice Aramini, David Lederer, Susan L. DiAngelo, Selim Arcasoy, Joshua R. Sonett, Hillary Robbins, Lory Shah, Joseph Costa, Andreacarola Urso Eur Respir J, 55 (3) 1900618; 10.1183/13993003.00618-2019
Antibiotic efficacy varies based on the infection model and treatment regimen for Pseudomonas aeruginosa Cristina Cigana, Serena Ranucci, Alice Rossi, Ida De Fino, Medede Melessike, Alessandra Bragonzi Eur Respir J, 55 (3) 1802456; 10.1183/13993003.02456-2018
Transcriptional biomarkers for predicting development of tuberculosis: progress and clinical considerations Hanif Esmail, Frank Cobelens, Delia Goletti Eur Respir J, 55 (3) 1901957; 10.1183/13993003.01957-2019
Diabetes is associated with genotypically drug-resistant tuberculosis Carolien Ruesen, Lidya Chaidir, Cesar Ugarte-Gil, Jakko van Ingen, Julia A. Critchley, Philip C. Hill, Rovina Ruslami, Prayudi Santoso, Martijn A. Huynen, Hazel M. Dockrell, David A.J. Moore, Bachti Alisjahbana, Reinout van Crevel Eur Respir J, 55 (3) 1901891; 10.1183/13993003.01891-2019
Routine survey of Mycobacterium tuberculosis isolates reveals nosocomial transmission Charlotte Genestet, Raphael Paret, Catherine Pichat, Jean-Luc Berland, Véronique Jacomo, Gerard Carret, Isabelle Fredenucci, Elisabeth Hodille, Jean-Philippe Rasigade, Sandrine Boisset, Anne Carricajo, Gérard Lina, Anne-Sophie Ronnaux-Baron, Jean-François Mornex, Jacqueline Grando, Agathe Sénéchal, Florence Ader, Oana Dumitrescu Eur Respir J, 55 (3) 1901888; 10.1183/13993003.01888-2019
Gene-based diagnosis of tuberculosis with a new-generation pathogen enrichment technique Sei Won Lee, Young Ae Kang, Choong Eun Jin, Ho Cheol Kim, Geun Su Noh, Hyo Joo Lee, Joung Ha Park, Yong Seo Koo, Yong Shin, Sung-Han Kim Eur Respir J, 55 (3) 1901885; 10.1183/13993003.01885-2019
A pressure-based single beat method for estimation of right ventricular ejection fraction: proof of concept Paul M. Heerdt, Vitaly Kheyfets, Sofia Charania, Ahmed Elassal, Inderjit Singh Eur Respir J, 55 (3) 1901635; 10.1183/13993003.01635-2019
Exertional dyspnoea–ventilation relationship to discriminate respiratory from cardiac impairment Franciele Plachi, Fernanda Machado Balzan, Luiz Felipe Fröhlich, Ricardo Gass, Nathalia Branco Mendes, Elisa Schroeder, Danilo C. Berton, Denis E. O'Donnell, J. Alberto Neder Eur Respir J, 55 (3) 1901518; 10.1183/13993003.01518-2019
Increased ventilation heterogeneity in asthma can be attributed to proximal bronchioles Brody Foy, David Kay, Salman Siddiqui, Chris Brightling, Manuel Paiva, Sylvia Verbanck Eur Respir J, 55 (3) 1901345; 10.1183/13993003.01345-2019
An evaluation of a throat discomfort visual analogue scale in chronic cough James H. Hull, Emil S. Walsted, Matthew J. Pavitt, Bethany Tidmarsh, Julia Selby Eur Respir J, 55 (3) 1901722; 10.1183/13993003.01722-2019
Upregulation of smooth muscle Rho-kinase protein expression in human asthma Lu Wang, Pasquale Chitano, Peter D. Paré, Chun Y. Seow Eur Respir J, 55 (3) 1901785; 10.1183/13993003.01785-2019
Something is changing in adherence to CPAP therapy: real world data after 1 year of treatment in patients with obstructive sleep apnoea Elisa Morrone, Andrea Giordano, Sonia Carli, Dina Visca, Fabio Rossato, Massimo Godio, Elena Paracchini, Sabrina Rossi, Bruno Balbi, Carlo Sacco, Alberto Braghiroli Eur Respir J, 55 (3) 1901419; 10.1183/13993003.01419-2019
Avoiding immortal time bias in observational studies Adam J.N. Raymakers, Mohsen Sadatsafavi, Don D. Sin, J. Mark FitzGerald, Carlo A. Marra, Larry D. Lynd Eur Respir J, 55 (3) 1902494; 10.1183/13993003.02494-2019
Avoiding immortal time bias in observational studies Samy Suissa, Pierre Ernst Eur Respir J, 55 (3) 2000138; 10.1183/13993003.00138-2020
More awareness is needed for severe acute respiratory syndrome coronavirus 2019 transmission through exhaled air during non-invasive respiratory support: experience from China Lili Guan, Luqian Zhou, Jinnong Zhang, Wei Peng, Rongchang Chen Eur Respir J, 55 (3) 2000352; 10.1183/13993003.00352-2020
Outcomes consequent to “early” COPD for interventional studies Stephen I. Rennard Eur Respir J, 55 (3) 1902380; 10.1183/13993003.02380-2019
Outcomes consequent to “early” COPD for interventional studies Yunus Çolak, Børge G. Nordestgaard, Jørgen Vestbo, Peter Lange, Shoaib Afzal Eur Respir J, 55 (3) 2000073; 10.1183/13993003.00073-2020
Systemic potency of fluticasone in asthma Brian Lipworth, Chris RuiWen Kuo, Rory Chan Eur Respir J, 55 (3) 2000104; 10.1183/13993003.00104-2020
WHO 2019 guidelines on drug-resistant tuberculosis treatment: based on evidence or expert opinion? Lorenzo Guglielmetti, Helena Huerga, Uzma Khan, Francis Varaine Eur Respir J, 55 (3) 1901935; 10.1183/13993003.01935-2019
WHO guidance on multidrug-resistant tuberculosis treatment: using and communicating the evidence Dennis Falzon, Holger J. Schünemann, Matteo Zignol, Fuad Mirzayev, Tereza Kasaeva Eur Respir J, 55 (3) 1902325; 10.1183/13993003.02325-2019
In addition to mTOR and JAK/STAT, NLRP3 inflammasome is another key pathway activated in sarcoidosis Nicolas Riteau, Jean-François Bernaudin Eur Respir J, 55 (3) 2000149; 10.1183/13993003.00149-2020
The NLRP3 inflammasome pathway is activated in sarcoidosis and involved in granuloma formation Christine Huppertz, Benedikt Jäger, Grazyna Wieczorek, Peggy Engelhard, Stephen J. Oliver, Franz-Georg Bauernfeind, Amanda Littlewood-Evans, Tobias Welte, Veit Hornung, Antje Prasse Eur Respir J, 55 (3) 1900119; 10.1183/13993003.00119-2019
Genetic susceptibility to asthma increases the vulnerability to indoor air pollution Anke Hüls, Aneesa Vanker, Diane Gray, Nastassja Koen, Julia L. MacIsaac, David T.S. Lin, Katia E. Ramadori, Peter D. Sly, Dan J. Stein, Michael S. Kobor, Heather J. Zar Eur Respir J, 55 (3) 1901831; 10.1183/13993003.01831-2019
Clinical utility of fractional exhaled nitric oxide in severe asthma management Andrew Menzies-Gow, Adel H. Mansur, Christopher E. Brightling Eur Respir J, 55 (3) 1901633; 10.1183/13993003.01633-2019
FEV₁ and MRI ventilation defect reversibility in asthma and COPD Hana Serajeddini, Rachel L. Eddy, Christopher Licskai, David G. McCormack, Grace Parraga Eur Respir J, 55 (3) 1901947; 10.1183/13993003.01947-2019
Avoiding ageism and promoting independence from reference equations in lung function testing of older adults Eralda Hegendörfer, Jean-Marie Degryse Eur Respir J, 55 (3) 2000033; 10.1183/13993003.00033-2020
Avoiding ageism and promoting independence from reference equations in lung function testing of older adults Johannes A. Luoto, Mats Pihlsgård Eur Respir J, 55 (3) 2000172; 10.1183/13993003.00172-2020
“Functional ageing in fibrotic interstitial lung disease: the impact of frailty on adverse health outcomes.” Sabina A. Guler, Joanne M. Kwan, Janice M. Leung, Nasreen Khalil, Pearce G. Wilcox and Christopher J. Ryerson. Eur Respir J 2020; 55: 1900647. Eur Respir J, 55 (3) 1950647; 10.1183/13993003.50647-2019