Crosstalk in chronic pulmonary diseases

Poster Discussion
Chairs: O. Burgy (Dijon, France), J. Baker (London, United Kingdom)

Late Breaking Abstract - Investigation of the epithelial-mesenchymal paracrine interactions in lung tissue repair and fibrosis. F. Conforti (Southampton, United Kingdom), R. Ridley (Southampton, United Kingdom), M. Jones (Southampton, United Kingdom), A. Alzetani (Southampton, United Kingdom), C. Brereton (Southampton, United Kingdom), Y. Wang (Southampton, United Kingdom), P. Skipp (Southampton, United Kingdom), L. Richeldi (Rome, Italy), D. Davies (southampton, United Kingdom)
Epithelial dysregulation in obese severe asthmatics with gastro-oesophageal reflux J. Perotin-Collard (Southampton, United Kingdom), J. Schofield (Southampton, United Kingdom), S. Wilson (Southampton, United Kingdom), J. Ward (Southampton, United Kingdom), J. Brandsma (Southampton, United Kingdom), F. Strazzeri (Southampton, United Kingdom), A. Bansal (Cambridge, United Kingdom), X. Yang (London, United Kingdom), A. Rowe (Buckinghamshire, United Kingdom), J. Corfield (Nottingham, United Kingdom), R. Lutter (Amsterdam, Netherlands), D. Shaw (Nottingham, United Kingdom), P. Bakke (Bergen, Norway), M. Caruso (Catania, Italy), B. Dahlén (Stockholm, Sweden), S. Fowler (Manchestere, United Kingdom), I. Horvath (Budapest, Hungary), P. Howarth (Southampton, United Kingdom), N. Krug (Hannover, Germany), P. Montuschi (Rome, Italy), M. Sanak (Krakow, Poland), T. Sandström (Umeå, Sweden), K. Sun (London, United Kingdom), I. Pandis (London, United Kingdom), C. Auffray (Lyon, France), B. De Meulder (Lyon, France), D. Lefaudeux (Lyon, France), J. Riley (Stockley Park, United Kingdom), A. Sousa (Stockley Park, United Kingdom), S. Dahlen (Stockholm, Sweden), I. Adcock (London, United Kingdom), K. Chung (London, United Kingdom), P. Sterk (Amsterdam, Netherlands), P. Skipp (Southampton, United Kingdom), J. Collins (Southampton, United Kingdom), D. Davies (Southampton, United Kingdom), R. Djukanovic (Southampton, United Kingdom)
IL33 receptor activation is IL33 isoform and receptor genotype specific M. Portelli (Nottingham, United Kingdom), M. Edwards (Stevenage, United Kingdom), M. Ketelaar (Groningen, Netherlands), C. Xu (Groningen, Netherlands), J. Hoffman (King of Prussia, PA, United States of America), D. Mayhew (King of Prussia, PA, United States of America), I. Hall (Nottingham, United Kingdom), M. Nawjin (Groningen, Netherlands), G. Koppelman (Groningen, Netherlands), A. Van Oosterhout (Stevenage, United Kingdom), I. Sayers (Nottingham, United Kingdom)
Role of DNA methylation in Muc5AC hyperexpression in severe asthma S. Letuve (Paris, France), C. Sallon (Paris, France), X. Yang (Paris, France), A. Dumay (Paris, France), S. Bedja (Paris, France), F. Hamidi (Paris, France), N. Guillou (Paris, France), P. Mordant (Paris, France), M. Pretolani (Paris, France), C. Taillé (Paris, France)
Sputum gene signature comparison study between U-BIOPRED and Australia asthma cohorts S. Sánchez-Ovando (Newcastle, Australia), S. Pavlidis (London, United Kingdom), P. Wark (Newcastle, Australia), K. Baines (Newcastle, Australia), D. Barker (Newcastle, Australia), I. Adcock (London, United Kingdom), K. Chung (London, United Kingdom), P. Gibson (Newcastle, Australia), J. Simpson (Newcastle, Australia)
Aspirin exacerbated respiratory disease transcriptome analysis using RNA-seq L. Teran Juarez (Mexico City, Mexico), P. Vellore Sureshkumar (Mexico City, Mexico), A. Jimenez Chobillon (Mexico City, Mexico)
Analysis of microRNA expression profile in adipose tissue during allergic inflammation in the rat D. Szczepankiewicz (Poznan, Poland), W. Langwinski (Poznan, Poland), E. Pruszynska-Oszmalek (Poznan, Poland), P. Kolodziejski (Poznan, Poland), A. Szczepankiewicz (Poznan, Poland)
Visfatin as a possible serum biomarker in COPD D. Dimov (Stara Zagora, Bulgaria), T. Tacheva (Stara Zagora, Bulgaria), Y. Zhelyazkova (Stara Zagora, Bulgaria), N. O'Donoghue (Stara Zagora, Bulgaria), D. Vlaykova (Stara Zagora, Bulgaria), T. Vlaykova (Stara Zagora, Bulgaria)
An in vitro method showing the atrophic effect of the COPD serum on healthy human myotubes M. Catteau (Montpellier, France), F. Gouzi (Montpellier, France), L. Blervaque (Montpellier, France), E. Passerieux (Montpellier, France), M. Blaquière (Montpellier, France), B. Ayoub (Montpellier, France), F. Bughin (Montpellier, France), J. Mercier (Montpellier, France), M. Hayot (Montpellier, France), P. Pomiès (Montpellier, France)
Using transcriptomics to understand the potential functions of lung function associated gene, GPR126 in human airway smooth muscle cells R. Hall (Nottingham, United Kingdom), M. Portelli (Nottingham, United Kingdom), I. Hall (Nottingham, United Kingdom), I. Sayers (Nottingham, United Kingdom)
In vitro genome editing using CRISPR/Cas9 to edit SERPINA1 PiZ mutation L. Banyuls (Valencia, Spain), D. Pellicer (Valencia, Spain), S. Castillo (Valencia, Spain), M. Magallón (Valencia, Spain), M. Navarro (Valencia, Spain), A. Escribano (Valencia, Spain), F. Dasí (Valencia, Spain)
Leukotriene C4 synthase deficiency causes spontaneous emphysematous changes in mice Y. Ishii (Montreal, Canada), T. Mcgovern (Montreal, Canada), U. Fujii (Montreal, Canada), E. Nakada (Montreal, Canada), S. Farahnak (Montreal, Canada), N. Khazaei (Montreal, Canada), J. Martin (Montreal, Canada)
Longitudinal effects of smoking cessation on DNA methylation in bronchial biopsies of COPD and asymptomatic smokers A. Faiz (Sydney, Australia), S. Rathnayake (Sydney, Australia), C. Vermeulen (Groningen, Netherlands), W. Timens (Groningen, Netherlands), W. Kooistra (Groningen, Netherlands), B. Oliver (Sydney, Australia), . Willemse (Groningen, Netherlands), N. Ten Hacken (Groningen, Netherlands), I. Heijink (Groningen, Netherlands), C. Brandsma (Groningen, Netherlands), M. Van Den Berge (Groningen, Netherlands)
Structural and clinical characterization of novel missense variants of SERPINA1 gene causing alpha-1 antitrypsin deficiency C. Esquinas (barcelona, Spain), I. Belmonte (barcelona, Spain), A. Gonzalez (barcelona, Spain), M. Barrecheguren (barcelona, Spain), A. Nuñez (barcelona, Spain), M. Sarasate (barcelona, Spain), E. Loeb (barcelona, Spain), E. Rodriguez (barcelona, Spain), F. Rodriguez-Frias (barcelona, Spain), M. Miravitlles (barcelona, Spain)
Plasma circulating miRNAs as diagnostic and prognostic biomarkers in alpha-1 antitrypsin deficiency. F. Dasi Fernandez (Valencia, Spain), S. Pastor (Valencia, Spain), M. Magallón (Valencia, Spain), S. Castillo (Valencia, Spain), D. Pellicer (Valencia, Spain), L. Bañuls (Valencia, Spain), M. Navarro-García (Valencia, Spain), A. Escribano (Valencia, Spain)
Investigation and functional enrichment analysis of the human gene interaction network with common gram-negative respiratory pathogens predicts possible association with lung adenocarcinoma. L. Giannakou (Larissa, Greece), A. Giannopoulos (Larissa, Greece), E. Rouka (Larissa, Greece), C. Hatzoglou (Larissa, Greece), K. Gourgoulianis (Larissa, Greece), S. Zarogiannis (Larissa, Greece)