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November

The European Respiratory Society's 10 Principles for Lung Health Ildikó Horváth, Maeve Barry, Guy Brusselle, Otto Chris Burghuber, Andrew Bush, Carlos Robalo Cordeiro, Mina Gaga, Christina Gratziou, Isabel Saraiva, Daiana Stolz, Thierry Troosters, Tobias Welte, Giovanni Battista Migliori, Guy Joos Eur Respir J, 52 (5) 1801373; 10.1183/13993003.01373-2018
The Severe Heterogeneous Asthma Research collaboration, Patient-centred (SHARP) ERS Clinical Research Collaboration: a new dawn in asthma research Ratko Djukanovic, Ian M. Adcock, Gary Anderson, Elisabeth H. Bel, Giorgio W. Canonica, Hui Cao, Kian Fan Chung, Donna E. Davies, Céline Genton, Toni Gibson-Latimer, Dominique Hamerlijnck, Elise Heuvelin, Renaud Louis, Stephanie Korn, Maxim Kots, Namhee Kwon, Riad Naddaf, Scott S. Wagers Eur Respir J, 52 (5) 1801671; 10.1183/13993003.01671-2018
The European Multicentre Bronchiectasis Audit and Research Collaboration (EMBARC) ERS Clinical Research Collaboration Stefano Aliberti, Eva Polverino, James D. Chalmers, Josje Altenburg, Michal Shteinberg, Pieter C. Goeminne, Tobias Welte, Amelia Shoemark, Marta Almagro, Francesco Blasi Eur Respir J, 52 (5) 1802074; 10.1183/13993003.02074-2018
Pirfenidone in the kaleidoscope: reflecting mechanisms through different angles Argyris Tzouvelekis, Paul J. Wolters Eur Respir J, 52 (5) 1802046; 10.1183/13993003.02046-2018
An inhaled “bifunctional” dual PDE3/4 inhibitor provides additional short-term improvements in lung function compared to existing classes of bronchodilator: implications for future treatment of COPD Mario Cazzola, Clive Page Eur Respir J, 52 (5) 1801675; 10.1183/13993003.01675-2018
The further paradoxes of asthma management: time for a new approach across the spectrum of asthma severity Richard Beasley, Grace Bird, James Harper, Mark Weatherall Eur Respir J, 52 (5) 1800694; 10.1183/13993003.00694-2018
Vitamin D binding protein: a new biomarker of disease severity in lymphangioleiomyomatosis Heng-Jia Liu, Elizabeth P. Henske Eur Respir J, 52 (5) 1801886; 10.1183/13993003.01886-2018
Happy ever after? A new assessment tool for long-term noninvasive ventilation: the S³-NIV questionnaire Anita K. Simonds Eur Respir J, 52 (5) 1801969; 10.1183/13993003.01969-2018
ERS technical standard on bronchial challenge testing: pathophysiology and methodology of indirect airway challenge testing Teal S. Hallstrand, Joerg D. Leuppi, Guy Joos, Graham L. Hall, Kai-Håkon Carlsen, David A. Kaminsky, Allan L. Coates, Donald W. Cockcroft, Bruce H. Culver, Zuzana Diamant, Gail M. Gauvreau, Ildiko Horvath, Frans H.C. de Jongh, Beth L. Laube, Peter J. Sterk, Jack Wanger Eur Respir J, 52 (5) 1801033; 10.1183/13993003.01033-2018
Evaluating the potential costs and impact of digital health technologies for tuberculosis treatment support Ntwali Placide Nsengiyumva, Benjamin Mappin-Kasirer, Olivia Oxlade, Mayara Bastos, Anete Trajman, Dennis Falzon, Kevin Schwartzman Eur Respir J, 52 (5) 1801363; 10.1183/13993003.01363-2018
Maternal blood pressure and hypertensive disorders during pregnancy and childhood respiratory morbidity: the Generation R Study Freke A. Wilmink, Herman T. den Dekker, Johan C. de Jongste, Irwin K.M. Reiss, Vincent W.V. Jaddoe, Eric A. Steegers, Liesbeth Duijts Eur Respir J, 52 (5) 1800378; 10.1183/13993003.00378-2018
Matching-adjusted indirect comparison of benralizumab versus interleukin-5 inhibitors for the treatment of severe asthma: a systematic review Arnaud Bourdin, Don Husereau, Nicolas Molinari, Sarowar Golam, Mohd Kashif Siddiqui, Leandro Lindner, Xiao Xu Eur Respir J, 52 (5) 1801393; 10.1183/13993003.01393-2018
Transcriptome profiling reveals the complexity of pirfenidone effects in idiopathic pulmonary fibrosis Grazyna Kwapiszewska, Anna Gungl, Jochen Wilhelm, Leigh M. Marsh, Helene Thekkekara Puthenparampil, Katharina Sinn, Miroslava Didiasova, Walter Klepetko, Djuro Kosanovic, Ralph T. Schermuly, Lukasz Wujak, Benjamin Weiss, Liliana Schaefer, Marc Schneider, Michael Kreuter, Andrea Olschewski, Werner Seeger, Horst Olschewski, Malgorzata Wygrecka Eur Respir J, 52 (5) 1800564; 10.1183/13993003.00564-2018
Investigating unilateral pleural effusions: the role of cytology David T. Arnold, Duneesha De Fonseka, Siobhan Perry, Anna Morley, John E. Harvey, Andrew Medford, Mary Brett, Nick A. Maskell Eur Respir J, 52 (5) 1801254; 10.1183/13993003.01254-2018
Patterns of regional lung physiology in cystic fibrosis using ventilation magnetic resonance imaging and multiple-breath washout Laurie J. Smith, Guilhem J. Collier, Helen Marshall, Paul J.C. Hughes, Alberto M. Biancardi, Martin Wildman, Ina Aldag, Noreen West, Alex Horsley, Jim M. Wild Eur Respir J, 52 (5) 1800821; 10.1183/13993003.00821-2018
Fibrinogen and the prediction of residual obstruction manifested after pulmonary embolism treatment Benjamin Planquette, Olivier Sanchez, James J. Marsh, Peter G. Chiles, Joseph Emmerich, Grégoire Le Gal, Guy Meyer, Tanya Wolfson, Anthony C. Gamst, Roger E. Moore, Gabriel B. Gugiu, Timothy A. Morris Eur Respir J, 52 (5) 1801467; 10.1183/13993003.01467-2018
Risk assessment in medically treated chronic thromboembolic pulmonary hypertension patients Marion Delcroix, Gerd Staehler, Henning Gall, Ekkehard Grünig, Matthias Held, Michael Halank, Hans Klose, Anton Vonk-Noordegraaf, Stephan Rosenkranz, Joanna Pepke-Zaba, Christian F. Opitz, J. Simon R. Gibbs, Tobias J. Lange, Iraklis Tsangaris, Doerte Huscher, David Pittrow, Karen M. Olsson, Marius M. Hoeper Eur Respir J, 52 (5) 1800248; 10.1183/13993003.00248-2018
The vitamin D binding protein axis modifies disease severity in lymphangioleiomyomatosis Suzanne Miller, Clare Coveney, Janice Johnson, Aliki-Eleni Farmaki, Nishant Gupta, Martin D. Tobin, Louise V. Wain, Francis X. McCormack, David J. Boocock, Simon R. Johnson Eur Respir J, 52 (5) 1800951; 10.1183/13993003.00951-2018
The short-term bronchodilator effects of the dual phosphodiesterase 3 and 4 inhibitor RPL554 in COPD Dave Singh, Katharine Abbott-Banner, Thomas Bengtsson, Kenneth Newman Eur Respir J, 52 (5) 1801074; 10.1183/13993003.01074-2018
Obstructive sleep apnoea as a risk factor for incident metabolic syndrome: a joined Episono and HypnoLaus prospective cohorts study Camila Hirotsu, Jose Haba-Rubio, Sonia M. Togeiro, Pedro Marques-Vidal, Luciano F. Drager, Peter Vollenweider, Gérard Waeber, Lia Bittencourt, Sergio Tufik, Raphael Heinzer Eur Respir J, 52 (5) 1801150; 10.1183/13993003.01150-2018
Detection of mild cognitive impairment in middle-aged and older adults with obstructive sleep apnoea Katia Gagnon, Andrée-Ann Baril, Jacques Montplaisir, Julie Carrier, Sirin Chami, Serge Gauthier, Chantal Lafond, Jean-François Gagnon, Nadia Gosselin Eur Respir J, 52 (5) 1801137; 10.1183/13993003.01137-2018
What is a COPD exacerbation? Current definitions, pitfalls, challenges and opportunities for improvement Victor Kim, Shawn D. Aaron Eur Respir J, 52 (5) 1801261; 10.1183/13993003.01261-2018
COPD biomarkers and phenotypes: opportunities for better outcomes with precision imaging George R. Washko, Grace Parraga Eur Respir J, 52 (5) 1801570; 10.1183/13993003.01570-2018
Use of three-dimensional organoids and lung-on-a-chip methods to study lung development, regeneration and disease Konstantinos Gkatzis, Sara Taghizadeh, Dongeun Huh, Didier Y.R. Stainier, Saverio Bellusci Eur Respir J, 52 (5) 1800876; 10.1183/13993003.00876-2018
Digital technologies and adherence in respiratory diseases: the road ahead John D. Blakey, Bruce G. Bender, Alexandra L. Dima, John Weinman, Guilherme Safioti, Richard W. Costello Eur Respir J, 52 (5) 1801147; 10.1183/13993003.01147-2018
Can we predict tuberculosis cure? What tools are available? Delia Goletti, Cecilia S. Lindestam Arlehamn, Thomas J. Scriba, Richard Anthony, Daniela Maria Cirillo, Tonino Alonzi, Claudia M. Denkinger, Frank Cobelens Eur Respir J, 52 (5) 1801089; 10.1183/13993003.01089-2018
Whole genome sequencing of Mycobacterium tuberculosis Andrea M. Cabibbe, Timothy M. Walker, Stefan Niemann, Daniela M. Cirillo Eur Respir J, 52 (5) 1801163; 10.1183/13993003.01163-2018
Safety of biweekly a₁-antitrypsin treatment in the RAPID programme Timm Greulich, Jan Chlumsky, Marion Wencker, Oliver Vit, Michael Fries, Thomas Chung, Amgad Shebl, Claus Vogelmeier, Kenneth R. Chapman, Noel G. McElvaney Eur Respir J, 52 (5) 1800897; 10.1183/13993003.00897-2018
Benefits of supervised community physical activity in obstructive sleep apnoea Mathieu Berger, Jean-Claude Barthélémy, David Hupin, Jérémy Raffin, Caroline Dupré, Pierre Labeix, Frédéric Costes, Jean-Michel Gaspoz, Frédéric Roche Eur Respir J, 52 (5) 1801592; 10.1183/13993003.01592-2018
Pulmonary function testing is safe in patients with thoracic aortic aneurysms Freddy Frost, Rob Peat, Joan McWean, Matt Shaw, Mark Field, Dilip Nazareth, Martin Walshaw Eur Respir J, 52 (5) 1800928; 10.1183/13993003.00928-2018
Systemic oxidative stress in congenital central hypoventilation syndrome Donatella Degl'Innocenti, Matteo Becatti, Marta Peruzzi, Claudia Fiorillo, Matteo Ramazzotti, Niccolò Nassi, Cinzia Arzilli, Raffaele Piumelli Eur Respir J, 52 (5) 1801497; 10.1183/13993003.01497-2018
Textural analysis demonstrates heterogeneous [¹⁸F]-fluorodeoxyglucose uptake in radiologically normal lung in patients with idiopathic pulmonary fibrosis Shamsuddeen A. Aliyu, Ged Avery, Christopher Cawthorne, Stephen J. Archibald, Timor Kadir, Julien M.Y. Willaime, Alyn H. Morice, Simon P. Hart, Michael G. Crooks Eur Respir J, 52 (5) 1801138; 10.1183/13993003.01138-2018
Statistical compared to clinical significance and the risk of misattribution Magnus Ekström, Miriam J. Johnson, David C. Currow Eur Respir J, 52 (5) 1801723; 10.1183/13993003.01723-2018
Statistical compared to clinical significance and the risk of misattribution Nicholas T. Vozoris, Peter C. Austin, Paula A. Rochon Eur Respir J, 52 (5) 1801868; 10.1183/13993003.01868-2018
European Union standard for tuberculosis care on treatment of multidrug-resistant tuberculosis following new World Health Organization recommendations Giovanni Battista Migliori, Giovanni Sotgiu, Senia Rosales-Klintz, Marieke J. van der Werf Eur Respir J, 52 (5) 1801617; 10.1183/13993003.01617-2018
Clofazimine does not lead to significant QT interval prolongation: a multicentre study Sanne M.H. Zweijpfenning, Hester van Groningen, Jakko van Ingen, Cecile Magis-Escurra, Martin J. Boeree, Dirk Wagner, Hannelore Bax, Claire Andrejak, Reinier Wener, Ananna Rahman, Heinke Kunst, Natalie Lorent, Marc A. Brouwer, Wouter Hoefsloot Eur Respir J, 52 (5) 1801386; 10.1183/13993003.01386-2018
“2017 ERS/ATS standards for single-breath carbon monoxide uptake in the lung.” Brian L. Graham, Vito Brusasco, Felip Burgos, Brendan G. Cooper, Robert Jensen, Adrian Kendrick, Neil R. MacIntyre, Bruce R. Thompson and Jack Wanger. Eur Respir J 2017; 49: 1600016. Eur Respir J, 52 (5) 1650016; 10.1183/13993003.50016-2016
Development and validation of a simple tool for the assessment of home noninvasive ventilation: the S³-NIV questionnaire Elise Dupuis-Lozeron, Grégoire Gex, Patrick Pasquina, Pierre-Olivier Bridevaux, Jean-Christian Borel, Paola M. Soccal, Wolfram Windisch, Jean-Louis Pépin, Jean-Paul Janssens, Dan Adler Eur Respir J, 52 (5) 1801182; 10.1183/13993003.011822018