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October

ERJ October Podcast: Causal inference studies Eur Respir J, 52 (4) 18E5204; 10.1183/13993003.E5204-2018
A new era for treatment of drug-resistant tuberculosis Neel R. Gandhi, James C.M. Brust, N. Sarita Shah Eur Respir J, 52 (4) 1801350; 10.1183/13993003.01350-2018
The Severe Paediatric Asthma Collaborative in Europe (SPACE) ERS Clinical Research Collaboration: enhancing participation of children with asthma in therapeutic trials of new biologics and receptor blockers Franca Rusconi, Ricardo M. Fernandes, Mariëlle W.H. Pijnenburg, Jonathan Grigg Eur Respir J, 52 (4) 1801665; 10.1183/13993003.01665-2018
The European Sleep Apnoea Database (ESADA) ERS Clinical Research Collaboration: past, present and future Maria R. Bonsignore, Jan Hedner Eur Respir J, 52 (4) 1801666; 10.1183/13993003.01666-2018
Escaping the Plato's cave of latent tuberculosis testing: a path for developers of predictive tests for risk of tuberculosis Morten Ruhwald, Roland Diel Eur Respir J, 52 (4) 1801616; 10.1183/13993003.01616-2018
Kudzu and sleeper cells: the varied ecology of respiratory infections Robert P. Dickson Eur Respir J, 52 (4) 1801607; 10.1183/13993003.01607-2018
Physical activity: the key to cardiometabolic risk reduction in obstructive sleep apnoea Monique Mendelson, Patrice Flore Eur Respir J, 52 (4) 1801775; 10.1183/13993003.01775-2018
Risk assessment in patients with systemic sclerosis and pulmonary arterial hypertension Karen M. Olsson, Marius M. Hoeper Eur Respir J, 52 (4) 1801745; 10.1183/13993003.01745-2018
Whither pulmonary rehabilitation? Will alternative modes help or hurt? Richard Casaburi Eur Respir J, 52 (4) 1801678; 10.1183/13993003.01678-2018
Breaking news: DNA damage and repair pathways in COPD and implications for pathogenesis and treatment Ian M. Adcock, Sharon Mumby, Gaetano Caramori Eur Respir J, 52 (4) 1801718; 10.1183/13993003.01718-2018
Optimisation of chemotherapy in the era of immunotherapy René Boosman, Jacobus (Sjaak) Adrianus Burgers Eur Respir J, 52 (4) 1801698; 10.1183/13993003.01698-2018
An evaluation framework for new tests that predict progression from tuberculosis infection to clinical disease Sandra V. Kik, Samuel Schumacher, Daniela Maria Cirillo, Gavin Churchyard, Catharina Boehme, Delia Goletti, Molebogeng X. Rangaka, Claudia M. Denkinger, Christian Lienhardt, Christopher Gilpin, Alberto Matteelli, Frank Cobelens Eur Respir J, 52 (4) 1800946; 10.1183/13993003.00946-2018
Evaluation of the airway microbiome in nontuberculous mycobacteria disease Imran Sulaiman, Benjamin G. Wu, Yonghua Li, Adrienne S. Scott, Patrick Malecha, Benjamin Scaglione, Jing Wang, Ashwin Basavaraj, Samuel Chung, Katrina Bantis, Joseph Carpenito, Jose C. Clemente, Nan Shen, Jamie Bessich, Samaan Rafeq, Gaetene Michaud, Jessica Donington, Charissa Naidoo, Grant Theron, Gail Schattner, Suzette Garofano, Rany Condos, David Kamelhar, Doreen Addrizzo-Harris, Leopoldo N. Segal Eur Respir J, 52 (4) 1800810; 10.1183/13993003.00810-2018
The “one airway, one disease” concept in light of Th2 inflammation Lisa Giovannini-Chami, Agnès Paquet, Céline Sanfiorenzo, Nicolas Pons, Julie Cazareth, Virginie Magnone, Kévin Lebrigand, Benoit Chevalier, Ambre Vallauri, Valérie Julia, Charles-Hugo Marquette, Brice Marcet, Sylvie Leroy, Pascal Barbry Eur Respir J, 52 (4) 1800437; 10.1183/13993003.00437-2018
Baseline patient factors impact on the clinical efficacy of benralizumab for severe asthma Eugene R. Bleecker, Michael E. Wechsler, J. Mark FitzGerald, Andrew Menzies-Gow, Yanping Wu, Ian Hirsch, Mitchell Goldman, Paul Newbold, James G. Zangrilli Eur Respir J, 52 (4) 1800936; 10.1183/13993003.00936-2018
Extensively drug-resistant tuberculosis in South Africa: genomic evidence supporting transmission in communities Sara C. Auld, N. Sarita Shah, Barun Mathema, Tyler S. Brown, Nazir Ismail, Shaheed Vally Omar, James C.M. Brust, Kristin N. Nelson, Salim Allana, Angela Campbell, Koleka Mlisana, Pravi Moodley, Neel R. Gandhi Eur Respir J, 52 (4) 1800246; 10.1183/13993003.00246-2018
Continuous positive airway pressure effect on visual acuity in patients with type 2 diabetes and obstructive sleep apnoea: a multicentre randomised controlled trial Sophie D. West, Benjamin Prudon, Joan Hughes, Rajen Gupta, Seid B. Mohammed, Stephen Gerry, John R. Stradling Eur Respir J, 52 (4) 1801177; 10.1183/13993003.01177-2018
Physical activity as a moderator for obstructive sleep apnoea and cardiometabolic risk in the EPISONO study Marcos Mônico-Neto, Hanna Karen Moreira Antunes, Ronaldo Vagner Thomatieli dos Santos, Vânia D'Almeida, Altay Alves Lino de Souza, Lia Rita Azeredo Bittencourt, Sergio Tufik Eur Respir J, 52 (4) 1701972; 10.1183/13993003.01972-2017
Haemodynamics and serial risk assessment in systemic sclerosis associated pulmonary arterial hypertension Jason Weatherald, Athénaïs Boucly, David Launay, Vincent Cottin, Grégoire Prévot, Delphine Bourlier, Claire Dauphin, Ari Chaouat, Laurent Savale, Xavier Jaïs, Mitja Jevnikar, Julie Traclet, Pascal De Groote, Gérald Simonneau, Eric Hachulla, Luc Mouthon, David Montani, Marc Humbert, Olivier Sitbon Eur Respir J, 52 (4) 1800678; 10.1183/13993003.00678-2018
Chronic blood exchange transfusions in the management of pre-capillary pulmonary hypertension complicating sickle cell disease Matthieu Turpin, Christelle Chantalat-Auger, Florence Parent, Françoise Driss, François Lionnet, Anoosha Habibi, Bernard Maître, Alice Huertas, Xavier Jaïs, Jason Weatherald, David Montani, Olivier Sitbon, Gérald Simonneau, Fréderic Galactéros, Marc Humbert, Pablo Bartolucci, Laurent Savale Eur Respir J, 52 (4) 1800272; 10.1183/13993003.00272-2018
Long-term efficacy and effectiveness of a behavioural and community-based exercise intervention (Urban Training) to increase physical activity in patients with COPD: a randomised controlled trial Ane Arbillaga-Etxarri, Elena Gimeno-Santos, Anael Barberan-Garcia, Eva Balcells, Marta Benet, Eulàlia Borrell, Nuria Celorrio, Anna Delgado, Carme Jané, Alicia Marin, Carlos Martín-Cantera, Mónica Monteagudo, Nuria Montellà, Laura Muñoz, Pilar Ortega, Diego A. Rodríguez, Robert Rodríguez-Roisin, Pere Simonet, Pere Torán-Monserrat, Jaume Torrent-Pallicer, Pere Vall-Casas, Jordi Vilaró, Judith Garcia-Aymerich Eur Respir J, 52 (4) 1800063; 10.1183/13993003.00063-2018
The DNA repair transcriptome in severe COPD Maor Sauler, Maxime Lamontagne, Eric Finnemore, Jose D. Herazo-Maya, John Tedrow, Xuchen Zhang, Julia E. Morneau, Frank Sciurba, Wim Timens, Peter D. Paré, Patty J. Lee, Naftali Kaminski, Yohan Bossé, Jose L. Gomez Eur Respir J, 52 (4) 1701994; 10.1183/13993003.01994-2017
Renal impairment during pemetrexed maintenance in patients with advanced nonsmall cell lung cancer: a cohort study Sabine Visser, Jeannine Huisbrink, Nils E. van ‘t Veer, Jermo J. van Toor, Anton J.M. van Boxem, Nico C. van Walree, Bruno H. Stricker, Joachim G.J.V. Aerts Eur Respir J, 52 (4) 1800884; 10.1183/13993003.00884-2018
Anti-tumour effect of low molecular weight heparin in localised lung cancer: a phase III clinical trial Guy Meyer, Benjamin Besse, Hélène Doubre, Anaïs Charles-Nelson, Sandro Aquilanti, Armine Izadifar, Reza Azarian, Isabelle Monnet, Corinne Lamour, Renaud Descourt, Gérard Oliviero, Laurent Taillade, Christos Chouaid, Frederique Giraud, Pierre-Emmanuel Falcoz, Marie-Pierre Revel, Virginie Westeel, Adrien Dixmier, Jean Tredaniel, Stéphanie Dehette, Chantal Decroisette, Alain Prevost, Eric Pichon, Elizabeth Fabre, Jean-Charles Soria, Sylvie Friard, Jean-Baptiste Stern, Laurence Jabot, Georges Dennewald, Gérard Pavy, Patrick Petitpretz, Jean-Marc Tourani, Marco Alifano, Gilles Chatellier, Philippe Girard Eur Respir J, 52 (4) 1801220; 10.1183/13993003.01220-2018
Myeloperoxidase oxidation of methionine associates with early cystic fibrosis lung disease Joshua D. Chandler, Camilla Margaroli, Hamed Horati, Matthew B. Kilgore, Mieke Veltman, H. Ken Liu, Alexander J. Taurone, Limin Peng, Lokesh Guglani, Karan Uppal, Young-Mi Go, Harm A.W.M. Tiddens, Bob J. Scholte, Rabindra Tirouvanziam, Dean P. Jones, Hettie M. Janssens Eur Respir J, 52 (4) 1801118; 10.1183/13993003.01118-2018
SPLUNC1 degradation by the cystic fibrosis mucosal environment drives airway surface liquid dehydration Megan J. Webster, Boris Reidel, Chong D. Tan, Arunava Ghosh, Neil E. Alexis, Scott H. Donaldson, Mehmet Kesimer, Carla M.P. Ribeiro, Robert Tarran Eur Respir J, 52 (4) 1800668; 10.1183/13993003.00668-2018
Consequences of long-term oral corticosteroid therapy and its side-effects in severe asthma in adults: a focused review of the impact data in the literature Timm Volmer, Timo Effenberger, Christoph Trautner, Roland Buhl Eur Respir J, 52 (4) 1800703; 10.1183/13993003.00703-2018
The mode of action of anticholinergics in asthma Reinoud Gosens, Nicholas Gross Eur Respir J, 52 (4) 1701247; 10.1183/13993003.01247-2017
Nuclear magnetic resonance-based metabolomics in respiratory medicine Debora Paris, Mauro Maniscalco, Andrea Motta Eur Respir J, 52 (4) 1801107; 10.1183/13993003.01107-2018
Risk assessment in scleroderma patients with newly diagnosed pulmonary arterial hypertension: application of the ESC/ERS risk prediction model Valentina Mercurio, Nermin Diab, Grace Peloquin, Traci Housten-Harris, Rachel Damico, Todd M. Kolb, Stephen C. Mathai, Paul M. Hassoun Eur Respir J, 52 (4) 1800497; 10.1183/13993003.00497-2018
Hands are vehicles for transmission of Streptococcus pneumoniae in novel controlled human infection study Victoria Connor, Esther German, Sherin Pojar, Elena Mitsi, Caroline Hales, Elissavet Nikolaou, Angela Hyder-Wright, Hugh Adler, Seher Zaidi, Helen Hill, Simon P. Jochems, Hassan Burhan, Neil French, Timothy Tobery, Jamie Rylance, Daniela M. Ferreira Eur Respir J, 52 (4) 1800599; 10.1183/13993003.00599-2018
The Mechanical Ventilation–Respiratory Distress Observation Scale as a surrogate of self-reported dyspnoea in intubated patients Maxens Decavèle, Frédérick Gay, Romain Persichini, Julien Mayaux, Capucine Morélot-Panzini, Thomas Similowski, Alexandre Demoule Eur Respir J, 52 (4) 1800598; 10.1183/13993003.00598-2018
Effect of the CXCR2 antagonist danirixin on symptoms and health status in COPD Aili L. Lazaar, Bruce E. Miller, Maggie Tabberer, John Yonchuk, Nancy Leidy, Claire Ambery, Jackie Bloomer, Henrik Watz, Ruth Tal-Singer Eur Respir J, 52 (4) 1801020; 10.1183/13993003.01020-2018
Reducing the need for carbon dioxide monitoring in the investigation of paediatric sleep disordered breathing Federica Trucco, Andrew Bush, Hui-Leng Tan Eur Respir J, 52 (4) 1801290; 10.1183/13993003.01290-2018
Risk factors for lung disease progression in children with cystic fibrosis Hafez Al Momani, Audrey Perry, Rhys Jones, Melissa McDonnell, Amaran Krishnan, Andrew Robertson, Mike Griffin, Robert Rutherford, Malcolm Brodlie, Jeff Pearson, Steve Bourke, Chris Ward Eur Respir J, 52 (4) 1801492; 10.1183/13993003.01492-2018
“Safety of nintedanib added to pirfenidone treatment for idiopathic pulmonary fibrosis.” Kevin R. Flaherty, Charlene D. Fell, J. Terrill Huggins, Hilario Nunes, Robert Sussman, Claudia Valenzuela, Ute Petzinger, John L. Stauffer, Frank Gilberg, Monica Bengus and Marlies Wijsenbeek. Eur Respir J 2018; 52: 1800230. Eur Respir J, 52 (4) 1850230; 10.1183/13993003.50230-2018