New developments in paediatric asthma

Poster Discussion
Chairs: R. Mozún (Bern, Switzerland), F. Midulla (Roma (RM), Italy)

Whole-genome sequencing of Costa Rican children with asthma identifies CRISPLD2 as a candidate gene for lung function B. Chawes (Copenhagen, Denmark), J. Hecker (Bonn, Germany), C. Lange (Boston, United States of America), S. Weiss (Boston, United States of America), J. Lasky-Su (Boston, United States of America)
Cord blood eosinophils and Type 2 Innate lymphoid cells are correlated in infants born to mothers with asthma during pregnancy G. Martins Costa Gomes (Newcaslte, Australia), P. De Gouveia Belinelo (Newcastle, Australia), M. R. Starkey (Newcastle, Australia), K. Jesson (Newcastle, Australia), P. M. Hansbro (Newcastle, Australia), V. E. Murphy (Newcastle, Australia), K. Hardaker (Sydney, Australia), P. D. Robinson (Sydney, Australia), P. D. Sly (Brisbane, Australia), P. G. Gibson (Newcastle, Australia), J. Mattes (Newcastle, Australia), A. M. Collison (Newcastle, Australia)
Topological data analysis (TDA) of U-BIOPRED paediatric peripheral blood gene expression identified asthma phenotypes characterised by alternative splicing of glucocorticoid receptor (GR) mRNA J. Schofield (Southampton, United Kingdom), J. Bigler (Seattle, United States of America), M. Boedigheimer (Thousand Oaks, United States of America), K. Affleck (Stevenage, United Kingdom), A. Taylor (Stevenage, United Kingdom), S. Pavlidis (London, United Kingdom), J. Riley (Stevenage, United Kingdom), F. Strazzeri (Southampton, United Kingdom), G. Roberts (Southampton, United Kingdom), J. Brandsma (Southampton, United Kingdom), A. Bansal (Cambridge, United Kingdom), B. Nicholas (Southampton, United Kingdom), Y. Xian (London, United Kingdom), A. Rowe (Cambridge, United States of America), J. Corfield (Nottingham, United Kingdom), S. Wilson (Southampton, United Kingdom), J. Ward (Southampton, United Kingdom), R. Lutter (Amsterdam, Netherlands), L. Fleming (London, United Kingdom), D. Shaw (Nottingham, United Kingdom), B. Per (Bergen, Norway), M. Caruso (Catania, Italy), S. Dahlen (Stockholm, Sweden), S. Fowler (Manchester, United Kingdom), S. Hashimoto (Manchester, United Kingdom), I. Horvath (Budapest, Hungary), P. Howarth (Southampton, United Kingdom), N. Krug (Hannover, Germany), P. Montuschi (Milan, Italy), M. Sanak (Krakow, Poland), T. Sandstrom (Umea, Sweden), F. Singer (Bern, Switzerland), K. Sun (London, United Kingdom), I. Pandis (London, United Kingdom), C. Auffray (Lyon, France), B. De Meulder (Lyon, France), D. Lefaudeux (Lyon, France), R. Knowles (Stevenage, United Kingdom), N. Fitch (Maasmechelen, Belgium), A. Sousa (Stevenage, United Kingdom), I. Adcock (London, United Kingdom), K. Chung (London, United Kingdom), P. Sterk (Amsterdam, Netherlands), P. Skipp (Southampton, United Kingdom), R. Djukanovic (Southampton, United Kingdom)
Weighted Gene Co-expression Network Analysis of blood paediatric samples from the U-BIOPRED study identifies oxidative stress association with asthma severity S. Pavlidis (London, United Kingdom), Y. Guo (London, United Kingdom), K. Sun (London, United Kingdom), B. De Meulder (Lyon, France), J. Riley (Stevenage, United Kingdom), K. Affleck (Stevenage, United Kingdom), A. Taylor (Stevenage, United Kingdom), J. Schofield (Southampton, United Kingdom), A. Rowe (Springhouse, United States of America), M. Loza (Springhouse, United States of America), F. Baribaud (Springhouse, United States of America), I. Pandis (high wycombe, United Kingdom), A. Sousa (Stockley Park, United Kingdom), J. Corfield (Nottingham, United Kingdom), R. Knowles (Stevenage, United Kingdom), R. Djukanovic (Southampton, United Kingdom), C. Auffray (Lyon, France), P. Sterk (Amsterdam, Netherlands), I. Adcock (London, United Kingdom), F. Chung (London, United Kingdom), S. Hashimoto (Amsterdam, Netherlands), L. Fleming (London, United Kingdom), G. Roberts (Southampton, United Kingdom)
Phenotype-endotype in very severe preschool wheezers:The P’titAsthme cohort M. Fayon (Bordeaux, France), V. Siao (Bordeaux, France), S. Blanchon (Toulouse, France), H. Begueret (Bordeaux, France), A. Benard (Bordeaux, France), P. Berger (Bordeaux, France)
Distinguishing wheezing phenotypes in childhood: a pooled analysis of five birth cohorts C. Oksel (London, United Kingdom), R. Granell (Bristol, United Kingdom), J. Henderson (Bristol, United Kingdom), A. Custovic (London, United Kingdom)
Incidence and risk factors of pediatric asthma exacerbations in a multinational, multidatabase cohort study E. Baan (Rotterdam, Netherlands), M. De Ridder (Rotterdam, Netherlands), M. Engelkes (Rotterdam, Netherlands), E. Svensson (Aarhus, Denmark), D. Prieto-Alhambra (Barcelona, Spain), F. Lapi (Florence, Italy), C. Giaquinto (Padova, Italy), G. Picelli (Padova, Italy), F. Albers (North Carolina, United States of America), L. Evitt (London, United Kingdom), E. Bradford (North Carolina, United States of America), M. Van Dyke (Upper Providence, PA, United States of America), P. Rijnbeek (Rotterdam, Netherlands), M. Sturkenboom (Utrecht, Netherlands), H. Janssens (Rotterdam, Netherlands), K. Verhamme (Rotterdam, Netherlands)
Are episodic viral wheeze and multiple-trigger wheeze distinct and constant patterns? M. Raaymakers (Breda, Netherlands), P. Brand (Zwolle, Netherlands), M. Pijnenburg (Rotterdam, Netherlands), A. Vaessen-Verberne (Breda, Netherlands)
Correlation between RINT values and echocardiographic indices in pre-school children with chronic cough and wheezing. G. Parisi (Catania, Italy), S. Manti (Messina, Italy), V. Giacchi (Catania, Italy), P. Sciacca (Catania, Italy), L. Tardino (Catania, Italy), C. Cuppari (Messina, Italy), C. Salpietro (Messina, Italy), A. Chikermane (Birmingham, United Kingdom), S. Leonardi (Catania, Italy)
Particles in exhaled air (PExA) in assessment of asthma in children M. Juusela (Helsinki, Finland), K. Malmström (Helsinki, Finland), V. Aaltonen (Helsinki, Finland), S. Sarna (Helsinki, Finland), E. Qvist (Helsinki, Finland)
ReCIVA breath sampling in pediatric asthma: a feasibility study K. Holden (Leicester, United Kingdom), T. Mcnally (Leicester, United Kingdom), D. Salman (Loughborough, United Kingdom), C. Beardsmore (Leicester, United Kingdom), W. Ibrahim (Leicester, United Kingdom), C. Brightling (Leicester, United Kingdom), S. Siddiqui (Leicester, United Kingdom), P. Thomas (Loughborough, United Kingdom), E. Gaillard (Leicester, United Kingdom)
Asthma reviews in primary care which include spirometry lead to improved asthma control in children D. Lo (Leicester, United Kingdom), L. Danvers (Leicester, United Kingdom), D. Roland (Leicester, United Kingdom), M. Richardson (Leicester, United Kingdom), Y. Yang (Oxford, United Kingdom), C. Beardsmore (Leicester, United Kingdom), A. Wilson (Leicester, United Kingdom), E. Gaillard (Leicester, United Kingdom)
Design and development of a simulation game for parents of preschool children with asthma: an evidence-based approach. D. Drummond (Paris, France), A. Tesniere (Paris, France), A. Hadchouel (Paris, France)
Substitution of outpatient care in asthmatic children by online monitoring:Barriers and facilitators for implementation L. van den Wijngaart (Nijmegen, Netherlands), W. Geense (Nijmegen, Netherlands), A. Boehmer (Rotterdam, Netherlands), M. Brouwer (Nijmegen, Netherlands), C. Hugen (Nijmegen, Netherlands), B. Van Ewijk (Hilversum/Blaricum, Netherlands), M. Koenen (Boxmeer, Netherlands), A. Landstra (Arnhem, Netherlands), L. Niers (Veldhoven, Netherlands), L. Van Onzenoort (Doetinchem, Netherlands), M. Ottink (Enschede, Netherlands), E. Rikkers-Mutsaerts (Leiden, Netherlands), I. Groothuis (Den Hague, Netherlands), A. Vaessen-Verberne (Breda, Netherlands), J. Roukema (Nijmegen, Netherlands), P. Merkus (Nijmegen, Netherlands)
Mepolizumab for severe eosinophilic asthma: a comparison of efficacy in children, adolescents, and adults A. Gupta (London, United Kingdom), J. Steinfeld (Philadelphia, PA, United States of America), R. Price (Stevenage, Hertfordshire, United Kingdom), J. Azmi (Stockley Park, Uxbridge, United Kingdom), E. Bradford (Research Triangle Park, NC, United States of America), S. Yancey (Research Triangle Park, NC, United States of America)